Predicted complex interactions
XCL1_HUMAN + CXCR2
SUMMARY
- Chemokine
- XCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR2 View partner entry
- Partner description
- UniProt: P25025; Gene: cxcr2_human; Family: Chemokine
- Interactions detected
- 71
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm30 | LYS 126 | 3.32x32 | HBAcceptor |
| VAL 1 | NTc.Cm30 | LYS 126 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm30 | GLU 127 | 3.33x33 | Cationic |
| VAL 1 | NTc.Cm30 | GLU 127 | 3.33x33 | VdWContact |
| VAL 1 | NTc.Cm30 | PRO 215 | 5.42x43 | Hydrophobic |
| VAL 1 | NTc.Cm30 | TYR 267 | 6.51x51 | Hydrophobic |
| VAL 1 | NTc.Cm30 | TYR 267 | 6.51x51 | VdWContact |
| VAL 1 | NTc.Cm30 | LEU 271 | 6.55x55 | Hydrophobic |
| GLY 2 | NTc.Cm29 | ARG 184 | 4.64x65 | HBAcceptor |
| GLY 2 | NTc.Cm29 | ARG 184 | 4.64x65 | VdWContact |
| GLY 2 | NTc.Cm29 | TYR 197 | 45.51x51 | VdWContact |
| GLU 4 | NTc.Cm27 | LYS 108 | 2.64x64 | Anionic |
| GLU 4 | NTc.Cm27 | LYS 108 | 2.64x64 | HBAcceptor |
| GLU 4 | NTc.Cm27 | LYS 108 | 2.64x64 | VdWContact |
| VAL 5 | NTc.Cm26 | TYR 197 | 45.51x51 | Hydrophobic |
| VAL 5 | NTc.Cm26 | TYR 197 | 45.51x51 | VdWContact |
| SER 6 | NTc.Cm25 | PRO 41 | - | VdWContact |
| ASP 7 | NTc.Cm24 | VAL 192 | - | Hydrophobic |
| LYS 8 | NTc.Cm23 | SER 189 | - | VdWContact |
| ARG 9 | NTc.Cm22 | PRO 38 | - | Hydrophobic |
| ARG 9 | NTc.Cm22 | PRO 38 | - | VdWContact |
| ARG 9 | NTc.Cm22 | CYS 39 | - | VdWContact |
| ARG 9 | NTc.Cm22 | GLU 40 | - | Cationic |
| ARG 9 | NTc.Cm22 | GLU 40 | - | VdWContact |
| THR 10 | NTc.Cm21 | CYS 39 | - | HBAcceptor |
| THR 10 | NTc.Cm21 | CYS 39 | - | VdWContact |
| VAL 12 | NTc.Cm19 | CYS 39 | - | VdWContact |
| VAL 12 | NTc.Cm19 | GLU 284 | - | Hydrophobic |
| VAL 12 | NTc.Cm19 | GLU 284 | - | VdWContact |
| VAL 12 | NTc.Cm19 | CYS 286 | 7.25x24 | VdWContact |
| VAL 12 | NTc.Cm19 | ARG 289 | 7.28x27 | Hydrophobic |
| SER 13 | NTc.Cm18 | ASP 35 | - | VdWContact |
| SER 13 | NTc.Cm18 | ALA 36 | - | VdWContact |
| THR 15 | NTc.Cm16 | LEU 33 | - | VdWContact |
| THR 15 | NTc.Cm16 | ALA 36 | - | VdWContact |
| GLN 17 | NTc.Cm14 | PHE 32 | - | Hydrophobic |
| GLN 17 | NTc.Cm14 | PHE 32 | - | VdWContact |
| ARG 18 | NTc.Cm13 | PHE 14 | - | CationPi |
| ARG 18 | NTc.Cm13 | PHE 14 | - | VdWContact |
| ARG 18 | NTc.Cm13 | GLU 18 | - | Cationic |
| ARG 18 | NTc.Cm13 | GLU 18 | - | HBDonor |
| ARG 18 | NTc.Cm13 | GLU 18 | - | VdWContact |
| LEU 19 | NTc.Cm12 | LEU 33 | - | Hydrophobic |
| PRO 20 | NTc.Cm11 | LEU 20 | - | Hydrophobic |
| PRO 20 | NTc.Cm11 | TYR 23 | - | Hydrophobic |
| SER 22 | NTc.Cm9 | TRP 15 | - | VdWContact |
| ARG 23 | NTc.Cm8 | TYR 23 | - | HBDonor |
| ARG 23 | NTc.Cm8 | TYR 23 | - | VdWContact |
| SER 33 | cxb1.1 | ARG 278 | 6.62x62 | VdWContact |
| SER 33 | cxb1.1 | ARG 289 | 7.28x27 | VdWContact |
| ARG 35 | cxb1.5 | ASN 202 | - | VdWContact |
| ILE 38 | cxb1.8 | PRO 38 | - | Hydrophobic |
| ARG 43 | cxb1.16 | TYR 25 | - | HBDonor |
| ARG 43 | cxb1.16 | TYR 25 | - | VdWContact |
| ARG 43 | cxb1.16 | SER 26 | - | HBDonor |
| ARG 43 | cxb1.16 | SER 26 | - | VdWContact |
| LEU 45 | B1.2 | LEU 29 | - | Hydrophobic |
| LEU 45 | B1.2 | LEU 29 | - | VdWContact |
| LYS 46 | B1.3 | ALA 37 | - | VdWContact |
| LYS 46 | B1.3 | PRO 38 | - | Hydrophobic |
| LYS 46 | B1.3 | GLU 40 | - | Cationic |
| LYS 46 | B1.3 | GLU 40 | - | HBDonor |
| LYS 46 | B1.3 | GLU 40 | - | VdWContact |
| VAL 47 | B1.4 | LEU 29 | - | Hydrophobic |
| VAL 47 | B1.4 | LEU 33 | - | Hydrophobic |
| VAL 47 | B1.4 | LEU 33 | - | VdWContact |
| VAL 47 | B1.4 | ALA 36 | - | Hydrophobic |
| VAL 47 | B1.4 | ALA 36 | - | VdWContact |
| CYS 48 | B1.5 | ALA 36 | - | HBDonor |
| CYS 48 | B1.5 | ALA 36 | - | VdWContact |
| CYS 48 | B1.5 | PRO 38 | - | VdWContact |
