Predicted complex interactions
CCL15_HUMAN + CXCR3
SUMMARY
- Chemokine
- CCL15_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 112
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PRO 20 | NTc.Cm33 | PHE 47 | 1.26x26 | Hydrophobic |
| PRO 20 | NTc.Cm33 | PHE 47 | 1.26x26 | VdWContact |
| VAL 21 | NTc.Cm32 | PHE 47 | 1.26x26 | VdWContact |
| VAL 21 | NTc.Cm32 | ARG 53 | 1.32x32 | Hydrophobic |
| VAL 21 | NTc.Cm32 | ARG 53 | 1.32x32 | VdWContact |
| VAL 22 | NTc.Cm31 | PHE 47 | 1.26x26 | Hydrophobic |
| VAL 22 | NTc.Cm31 | PHE 47 | 1.26x26 | VdWContact |
| VAL 22 | NTc.Cm31 | LEU 198 | - | Hydrophobic |
| VAL 22 | NTc.Cm31 | LEU 198 | - | VdWContact |
| LEU 23 | NTc.Cm30 | LEU 49 | 1.28x28 | Hydrophobic |
| LEU 23 | NTc.Cm30 | LEU 49 | 1.28x28 | VdWContact |
| LEU 23 | NTc.Cm30 | PHE 51 | 1.30x30 | Hydrophobic |
| LEU 23 | NTc.Cm30 | PHE 51 | 1.30x30 | VdWContact |
| LEU 23 | NTc.Cm30 | LEU 56 | 1.35x35 | Hydrophobic |
| LEU 23 | NTc.Cm30 | LEU 56 | 1.35x35 | VdWContact |
| ASN 24 | NTc.Cm29 | HIS 202 | - | Hydrophobic |
| ASN 24 | NTc.Cm29 | HIS 202 | - | VdWContact |
| SER 25 | NTc.Cm28 | TYR 60 | 1.39x39 | HBDonor |
| SER 25 | NTc.Cm28 | TYR 60 | 1.39x39 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 60 | 1.39x39 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 109 | 2.60x60 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 109 | 2.60x60 | PiStacking |
| PHE 26 | NTc.Cm27 | TRP 109 | 2.60x60 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 308 | 7.43x42 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 308 | 7.43x42 | VdWContact |
| HIS 27 | NTc.Cm26 | TYR 271 | 6.51x51 | Hydrophobic |
| HIS 27 | NTc.Cm26 | LYS 300 | 7.35x34 | Hydrophobic |
| HIS 27 | NTc.Cm26 | SER 304 | 7.39x38 | VdWContact |
| PHE 28 | NTc.Cm25 | LEU 198 | - | Hydrophobic |
| PHE 28 | NTc.Cm25 | LEU 198 | - | VdWContact |
| PHE 28 | NTc.Cm25 | HIS 202 | - | Hydrophobic |
| PHE 28 | NTc.Cm25 | HIS 202 | - | PiStacking |
| ALA 29 | NTc.Cm24 | GLN 45 | 1.24x24 | Hydrophobic |
| ALA 29 | NTc.Cm24 | GLN 45 | 1.24x24 | VdWContact |
| ALA 29 | NTc.Cm24 | ASP 297 | 7.32x31 | Hydrophobic |
| ALA 30 | NTc.Cm23 | GLN 45 | 1.24x24 | VdWContact |
| ALA 30 | NTc.Cm23 | GLN 204 | 45.51x51 | VdWContact |
| ASP 31 | NTc.Cm22 | PRO 42 | - | Hydrophobic |
| ASP 31 | NTc.Cm22 | GLN 45 | 1.24x24 | HBAcceptor |
| ASP 31 | NTc.Cm22 | GLN 45 | 1.24x24 | VdWContact |
| ASP 31 | NTc.Cm22 | ARG 197 | - | Anionic |
| ASP 31 | NTc.Cm22 | ARG 197 | - | HBAcceptor |
| ASP 31 | NTc.Cm22 | ARG 197 | - | VdWContact |
| CYS 32 | NTc.Cm21 | CYS 43 | - | HBAcceptor |
| CYS 32 | NTc.Cm21 | CYS 43 | - | VdWContact |
| CYS 32 | NTc.Cm21 | GLU 293 | 7.28x27 | Hydrophobic |
| THR 34 | NTc.Cm19 | CYS 43 | - | VdWContact |
| THR 34 | NTc.Cm19 | CYS 290 | 7.25x24 | VdWContact |
| ILE 37 | NTc.Cm16 | CYS 38 | - | Hydrophobic |
| GLN 39 | NTc.Cm14 | TYR 29 | - | HBAcceptor |
| PRO 42 | NTc.Cm11 | TYR 29 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | TYR 29 | - | VdWContact |
| PRO 42 | NTc.Cm11 | CYS 37 | - | VdWContact |
| LEU 45 | NTc.Cm8 | CYS 37 | - | Hydrophobic |
| MET 46 | NTc.Cm7 | CYS 38 | - | VdWContact |
| PHE 50 | NTc.Cm3 | ARG 197 | - | Hydrophobic |
| SER 53 | CX.1 | GLN 204 | 45.51x51 | HBDonor |
| SER 53 | CX.1 | GLN 204 | 45.51x51 | VdWContact |
| SER 54 | CX.5 | TYR 205 | 45.52x52 | HBDonor |
| SER 54 | CX.5 | TYR 205 | 45.52x52 | VdWContact |
| SER 54 | CX.5 | ASN 206 | - | VdWContact |
| SER 54 | CX.5 | PHE 207 | - | HBAcceptor |
| SER 54 | CX.5 | PHE 207 | - | VdWContact |
| SER 54 | CX.5 | ARG 212 | 5.35x36 | HBAcceptor |
| SER 54 | CX.5 | ARG 212 | 5.35x36 | VdWContact |
| GLU 55 | cxb1.1 | GLN 204 | 45.51x51 | HBAcceptor |
| GLU 55 | cxb1.1 | GLN 204 | 45.51x51 | Hydrophobic |
| GLU 55 | cxb1.1 | GLN 204 | 45.51x51 | VdWContact |
| GLU 55 | cxb1.1 | TYR 205 | 45.52x52 | HBAcceptor |
| GLU 55 | cxb1.1 | TYR 205 | 45.52x52 | Hydrophobic |
| GLU 55 | cxb1.1 | TYR 205 | 45.52x52 | VdWContact |
| GLU 55 | cxb1.1 | ARG 212 | 5.35x36 | HBAcceptor |
| GLU 55 | cxb1.1 | ARG 212 | 5.35x36 | VdWContact |
| CYS 56 | cxb1.2 | ARG 212 | 5.35x36 | HBAcceptor |
| CYS 56 | cxb1.2 | ARG 212 | 5.35x36 | VdWContact |
| SER 57 | cxb1.5 | ARG 288 | - | HBAcceptor |
| SER 57 | cxb1.5 | ARG 288 | - | VdWContact |
| SER 57 | cxb1.5 | GLU 293 | 7.28x27 | HBDonor |
| SER 57 | cxb1.5 | GLU 293 | 7.28x27 | VdWContact |
| LYS 58 | cxb1.6 | ARG 288 | - | VdWContact |
| PRO 59 | cxb1.7 | GLN 209 | 5.32x33 | VdWContact |
| ILE 62 | cxb1.11 | PRO 42 | - | Hydrophobic |
| ILE 62 | cxb1.11 | PRO 42 | - | VdWContact |
| LYS 67 | B1.2 | SER 34 | - | HBDonor |
| LYS 67 | B1.2 | SER 34 | - | VdWContact |
| LYS 67 | B1.2 | ASP 35 | - | Cationic |
| LYS 67 | B1.2 | ASP 35 | - | HBDonor |
| LYS 67 | B1.2 | ASP 35 | - | VdWContact |
| ARG 69 | B1.4 | ASP 35 | - | Cationic |
| ARG 69 | B1.4 | ASP 35 | - | HBDonor |
| ARG 69 | B1.4 | ASP 35 | - | VdWContact |
| ARG 69 | B1.4 | CYS 37 | - | HBDonor |
| ARG 69 | B1.4 | CYS 37 | - | VdWContact |
| GLN 70 | B1.5 | PRO 41 | - | VdWContact |
| GLN 70 | B1.5 | PRO 42 | - | Hydrophobic |
| GLN 70 | B1.5 | PRO 42 | - | VdWContact |
| GLN 70 | B1.5 | ARG 197 | - | VdWContact |
| VAL 71 | B1.6 | CYS 38 | - | Hydrophobic |
| VAL 71 | B1.6 | CYS 38 | - | VdWContact |
| CYS 72 | B1.7 | SER 40 | - | HBDonor |
| CYS 72 | B1.7 | SER 40 | - | VdWContact |
| CYS 72 | B1.7 | PRO 42 | - | VdWContact |
| TYR 90 | b2b3.12 | GLU 196 | - | Hydrophobic |
| TYR 90 | b2b3.12 | GLU 196 | - | VdWContact |
| SER 91 | B3.1 | GLU 196 | - | VdWContact |
| ILE 92 | B3.2 | HIS 194 | - | Hydrophobic |
| ILE 92 | B3.2 | HIS 194 | - | VdWContact |
| ILE 92 | B3.2 | GLU 196 | - | HBDonor |
| ILE 92 | B3.2 | GLU 196 | - | Hydrophobic |
| ILE 92 | B3.2 | GLU 196 | - | VdWContact |
| ILE 92 | B3.2 | ASN 199 | - | Hydrophobic |
| ILE 92 | B3.2 | ASN 199 | - | VdWContact |
