Predicted complex interactions
CCL16_HUMAN + CXCR3
SUMMARY
- Chemokine
- CCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 165
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm36 | GLN 204 | 45.51x51 | VdWContact |
| PRO 2 | NTc.Cm35 | GLN 204 | 45.51x51 | VdWContact |
| PRO 2 | NTc.Cm35 | TYR 205 | 45.52x52 | HBAcceptor |
| PRO 2 | NTc.Cm35 | TYR 205 | 45.52x52 | Hydrophobic |
| PRO 2 | NTc.Cm35 | TYR 205 | 45.52x52 | VdWContact |
| PRO 2 | NTc.Cm35 | ARG 212 | 5.35x36 | VdWContact |
| LYS 3 | NTc.Cm34 | ASP 52 | 1.31x31 | Cationic |
| LYS 3 | NTc.Cm34 | HIS 202 | - | Hydrophobic |
| LYS 3 | NTc.Cm34 | CYS 203 | 45.50x50 | VdWContact |
| LYS 3 | NTc.Cm34 | GLN 204 | 45.51x51 | VdWContact |
| VAL 4 | NTc.Cm33 | TRP 109 | 2.60x60 | Hydrophobic |
| VAL 4 | NTc.Cm33 | TRP 109 | 2.60x60 | VdWContact |
| VAL 4 | NTc.Cm33 | LEU 190 | 4.64x65 | Hydrophobic |
| VAL 4 | NTc.Cm33 | LEU 190 | 4.64x65 | VdWContact |
| VAL 4 | NTc.Cm33 | CYS 203 | 45.50x50 | HBDonor |
| VAL 4 | NTc.Cm33 | CYS 203 | 45.50x50 | Hydrophobic |
| VAL 4 | NTc.Cm33 | CYS 203 | 45.50x50 | VdWContact |
| PRO 5 | NTc.Cm32 | TRP 109 | 2.60x60 | Hydrophobic |
| PRO 5 | NTc.Cm32 | PHE 131 | 3.32x32 | Hydrophobic |
| PRO 5 | NTc.Cm32 | PHE 131 | 3.32x32 | VdWContact |
| PRO 5 | NTc.Cm32 | TYR 308 | 7.43x42 | Hydrophobic |
| PRO 5 | NTc.Cm32 | TYR 308 | 7.43x42 | VdWContact |
| GLU 6 | NTc.Cm31 | ARG 212 | 5.35x36 | Anionic |
| GLU 6 | NTc.Cm31 | ARG 212 | 5.35x36 | VdWContact |
| GLU 6 | NTc.Cm31 | ARG 216 | 5.39x40 | Anionic |
| GLU 6 | NTc.Cm31 | ARG 216 | 5.39x40 | HBAcceptor |
| GLU 6 | NTc.Cm31 | ARG 216 | 5.39x40 | VdWContact |
| GLU 6 | NTc.Cm31 | LYS 300 | 7.35x34 | Anionic |
| GLU 6 | NTc.Cm31 | LYS 300 | 7.35x34 | HBAcceptor |
| GLU 6 | NTc.Cm31 | LYS 300 | 7.35x34 | Hydrophobic |
| GLU 6 | NTc.Cm31 | LYS 300 | 7.35x34 | VdWContact |
| TRP 7 | NTc.Cm30 | LEU 56 | 1.35x35 | Hydrophobic |
| TRP 7 | NTc.Cm30 | LEU 56 | 1.35x35 | VdWContact |
| TRP 7 | NTc.Cm30 | TYR 60 | 1.39x39 | Hydrophobic |
| TRP 7 | NTc.Cm30 | TYR 60 | 1.39x39 | VdWContact |
| TRP 7 | NTc.Cm30 | TRP 109 | 2.60x60 | Hydrophobic |
| TRP 7 | NTc.Cm30 | TRP 109 | 2.60x60 | VdWContact |
| TRP 7 | NTc.Cm30 | PHE 131 | 3.32x32 | PiStacking |
| TRP 7 | NTc.Cm30 | LYS 300 | 7.35x34 | Hydrophobic |
| TRP 7 | NTc.Cm30 | SER 301 | 7.36x35 | VdWContact |
| TRP 7 | NTc.Cm30 | SER 304 | 7.39x38 | VdWContact |
| TRP 7 | NTc.Cm30 | TYR 308 | 7.43x42 | HBDonor |
| TRP 7 | NTc.Cm30 | TYR 308 | 7.43x42 | Hydrophobic |
| TRP 7 | NTc.Cm30 | TYR 308 | 7.43x42 | VdWContact |
| VAL 8 | NTc.Cm29 | TRP 109 | 2.60x60 | Hydrophobic |
| THR 10 | NTc.Cm27 | LEU 49 | 1.28x28 | Hydrophobic |
| THR 10 | NTc.Cm27 | LEU 49 | 1.28x28 | VdWContact |
| THR 10 | NTc.Cm27 | LEU 198 | - | Hydrophobic |
| THR 10 | NTc.Cm27 | LEU 198 | - | VdWContact |
| THR 10 | NTc.Cm27 | HIS 202 | - | Hydrophobic |
| PRO 11 | NTc.Cm26 | GLN 45 | 1.24x24 | Hydrophobic |
| PRO 11 | NTc.Cm26 | GLN 45 | 1.24x24 | VdWContact |
| PRO 11 | NTc.Cm26 | SER 48 | 1.27x27 | VdWContact |
| PRO 11 | NTc.Cm26 | LEU 49 | 1.28x28 | Hydrophobic |
| PRO 11 | NTc.Cm26 | LEU 49 | 1.28x28 | VdWContact |
| SER 12 | NTc.Cm25 | GLN 45 | 1.24x24 | VdWContact |
| SER 12 | NTc.Cm25 | ARG 197 | - | HBAcceptor |
| SER 12 | NTc.Cm25 | ARG 197 | - | VdWContact |
| SER 12 | NTc.Cm25 | LEU 198 | - | VdWContact |
| THR 13 | NTc.Cm24 | PRO 42 | - | Hydrophobic |
| THR 13 | NTc.Cm24 | PRO 42 | - | VdWContact |
| THR 13 | NTc.Cm24 | CYS 43 | - | VdWContact |
| THR 13 | NTc.Cm24 | PRO 44 | - | VdWContact |
| THR 13 | NTc.Cm24 | ARG 197 | - | HBAcceptor |
| THR 13 | NTc.Cm24 | ARG 197 | - | VdWContact |
| CYS 14 | NTc.Cm23 | CYS 43 | - | HBAcceptor |
| CYS 14 | NTc.Cm23 | CYS 43 | - | VdWContact |
| CYS 14 | NTc.Cm23 | ARG 197 | - | Anionic |
| LEU 16 | NTc.Cm21 | CYS 43 | - | VdWContact |
| LEU 16 | NTc.Cm21 | ARG 288 | - | Hydrophobic |
| LEU 16 | NTc.Cm21 | ARG 288 | - | VdWContact |
| LEU 16 | NTc.Cm21 | ASN 289 | 7.24x23 | VdWContact |
| LEU 16 | NTc.Cm21 | CYS 290 | 7.25x24 | Hydrophobic |
| LEU 16 | NTc.Cm21 | CYS 290 | 7.25x24 | VdWContact |
| LEU 16 | NTc.Cm21 | GLU 293 | 7.28x27 | VdWContact |
| LYS 17 | NTc.Cm20 | SER 40 | - | VdWContact |
| TYR 19 | NTc.Cm18 | SER 40 | - | VdWContact |
| LEU 23 | NTc.Cm14 | CYS 37 | - | VdWContact |
| ARG 26 | NTc.Cm11 | GLU 33 | - | Cationic |
| ARG 26 | NTc.Cm11 | GLU 33 | - | HBDonor |
| ARG 26 | NTc.Cm11 | GLU 33 | - | VdWContact |
| LEU 27 | NTc.Cm10 | TYR 29 | - | Hydrophobic |
| LEU 27 | NTc.Cm10 | TYR 29 | - | VdWContact |
| VAL 29 | NTc.Cm8 | LEU 19 | - | Hydrophobic |
| VAL 29 | NTc.Cm8 | LEU 20 | - | Hydrophobic |
| VAL 29 | NTc.Cm8 | PHE 23 | - | Hydrophobic |
| VAL 29 | NTc.Cm8 | PHE 23 | - | VdWContact |
| TYR 31 | NTc.Cm6 | VAL 5 | - | Hydrophobic |
| TYR 31 | NTc.Cm6 | VAL 5 | - | VdWContact |
| TYR 31 | NTc.Cm6 | HIS 8 | - | Hydrophobic |
| TYR 31 | NTc.Cm6 | HIS 8 | - | VdWContact |
| LYS 33 | NTc.Cm4 | VAL 5 | - | Hydrophobic |
| LYS 33 | NTc.Cm4 | VAL 5 | - | VdWContact |
| LYS 33 | NTc.Cm4 | GLU 196 | - | Cationic |
| LYS 33 | NTc.Cm4 | GLU 196 | - | HBDonor |
| LYS 33 | NTc.Cm4 | GLU 196 | - | VdWContact |
| LYS 33 | NTc.Cm4 | ARG 197 | - | VdWContact |
| ALA 34 | NTc.Cm3 | ARG 197 | - | VdWContact |
| LEU 35 | NTc.Cm2 | LEU 3 | - | Hydrophobic |
| ASN 36 | NTc.Cm1 | ASP 195 | - | HBDonor |
| ASN 36 | NTc.Cm1 | ASP 195 | - | VdWContact |
| CYS 37 | CX.1 | ARG 197 | - | Anionic |
| CYS 37 | CX.1 | ARG 197 | - | VdWContact |
| HIS 38 | CX.5 | GLN 209 | 5.32x33 | VdWContact |
| HIS 38 | CX.5 | ASP 282 | 6.62x62 | VdWContact |
| HIS 38 | CX.5 | ARG 288 | - | PiCation |
| HIS 38 | CX.5 | ARG 288 | - | VdWContact |
| ILE 43 | cxb1.7 | PRO 42 | - | Hydrophobic |
| VAL 45 | cxb1.10 | LEU 20 | - | Hydrophobic |
| LYS 47 | cxb1.14 | PHE 23 | - | Hydrophobic |
| LYS 47 | cxb1.14 | PHE 23 | - | VdWContact |
| LYS 47 | cxb1.14 | TYR 27 | - | CationPi |
| LYS 47 | cxb1.14 | TYR 27 | - | Hydrophobic |
| LYS 47 | cxb1.14 | TYR 27 | - | VdWContact |
| LYS 47 | cxb1.14 | TYR 29 | - | Hydrophobic |
| LYS 47 | cxb1.14 | TYR 29 | - | VdWContact |
| ARG 48 | cxb1.15 | TYR 29 | - | CationPi |
| ARG 48 | cxb1.15 | TYR 29 | - | HBDonor |
| ARG 48 | cxb1.15 | TYR 29 | - | Hydrophobic |
| ARG 48 | cxb1.15 | TYR 29 | - | VdWContact |
| ASN 49 | cxb1.16 | LEU 20 | - | Hydrophobic |
| ASN 49 | cxb1.16 | LEU 20 | - | VdWContact |
| ARG 50 | B1.1 | CYS 37 | - | HBDonor |
| ARG 50 | B1.1 | CYS 37 | - | VdWContact |
| GLU 51 | B1.2 | PRO 41 | - | VdWContact |
| GLU 51 | B1.2 | PRO 42 | - | Hydrophobic |
| GLU 51 | B1.2 | PRO 42 | - | VdWContact |
| VAL 52 | B1.3 | CYS 38 | - | Hydrophobic |
| VAL 52 | B1.3 | CYS 38 | - | VdWContact |
| CYS 53 | B1.4 | SER 40 | - | HBDonor |
| CYS 53 | B1.4 | SER 40 | - | VdWContact |
| CYS 53 | B1.4 | PRO 42 | - | VdWContact |
| PRO 56 | B1.7 | LEU 3 | - | Hydrophobic |
| GLN 62 | b1b2.14 | LEU 3 | - | VdWContact |
| ILE 65 | B2.2 | VAL 5 | - | Hydrophobic |
| ILE 65 | B2.2 | HIS 8 | - | HBAcceptor |
| ILE 65 | B2.2 | HIS 8 | - | VdWContact |
| ASP 67 | B2.4 | HIS 8 | - | VdWContact |
| PRO 68 | B2.5 | HIS 8 | - | VdWContact |
| LEU 70 | b2b3.2 | HIS 8 | - | VdWContact |
| PRO 71 | b2b3.4 | LEU 11 | - | Hydrophobic |
| PRO 71 | b2b3.4 | LEU 11 | - | VdWContact |
| LEU 72 | b2b3.11 | HIS 8 | - | Hydrophobic |
| LEU 72 | b2b3.11 | VAL 10 | - | Hydrophobic |
| LEU 72 | b2b3.11 | VAL 10 | - | VdWContact |
| LEU 72 | b2b3.11 | LEU 11 | - | HBAcceptor |
| LEU 72 | b2b3.11 | LEU 11 | - | VdWContact |
| LEU 72 | b2b3.11 | GLU 196 | - | VdWContact |
| LEU 73 | b2b3.12 | LEU 11 | - | Hydrophobic |
| LEU 73 | b2b3.12 | LEU 11 | - | VdWContact |
| LEU 73 | b2b3.12 | VAL 16 | - | Hydrophobic |
| LEU 73 | b2b3.12 | VAL 16 | - | VdWContact |
| PRO 74 | B3.1 | LEU 11 | - | VdWContact |
| PRO 74 | B3.1 | VAL 16 | - | Hydrophobic |
| PRO 74 | B3.1 | VAL 16 | - | VdWContact |
| THR 75 | B3.2 | ARG 197 | - | HBDonor |
| THR 75 | B3.2 | ARG 197 | - | Hydrophobic |
| THR 75 | B3.2 | ARG 197 | - | VdWContact |
| THR 75 | B3.2 | LEU 198 | - | VdWContact |
| ASN 77 | B3.4 | ASP 13 | - | HBDonor |
| ASN 77 | B3.4 | ASP 13 | - | VdWContact |
| LEU 78 | b3h.1 | ASP 46 | 1.25x25 | Hydrophobic |
| LEU 78 | b3h.1 | ASP 46 | 1.25x25 | VdWContact |
| LEU 78 | b3h.1 | ASN 50 | 1.29x29 | VdWContact |
| THR 80 | b3h.3 | ASP 13 | - | Hydrophobic |
