Predicted complex interactions
CCL18_HUMAN + CXCR3
SUMMARY
- Chemokine
- CCL18_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 85
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm29 | PHE 131 | 3.32x32 | Hydrophobic |
| ALA 1 | NTc.Cm29 | PHE 131 | 3.32x32 | VdWContact |
| ALA 1 | NTc.Cm29 | TYR 271 | 6.51x51 | Hydrophobic |
| GLN 2 | NTc.Cm28 | LEU 190 | 4.64x65 | Hydrophobic |
| GLN 2 | NTc.Cm28 | GLN 204 | 45.51x51 | VdWContact |
| GLN 2 | NTc.Cm28 | TYR 205 | 45.52x52 | HBAcceptor |
| GLN 2 | NTc.Cm28 | TYR 205 | 45.52x52 | Hydrophobic |
| GLN 2 | NTc.Cm28 | TYR 205 | 45.52x52 | VdWContact |
| VAL 3 | NTc.Cm27 | LEU 56 | 1.35x35 | Hydrophobic |
| VAL 3 | NTc.Cm27 | LEU 56 | 1.35x35 | VdWContact |
| VAL 3 | NTc.Cm27 | SER 301 | 7.36x35 | VdWContact |
| VAL 3 | NTc.Cm27 | SER 304 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | TYR 308 | 7.43x42 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 308 | 7.43x42 | VdWContact |
| GLY 4 | NTc.Cm26 | ASP 52 | 1.31x31 | VdWContact |
| THR 5 | NTc.Cm25 | ASP 52 | 1.31x31 | HBDonor |
| THR 5 | NTc.Cm25 | ASP 52 | 1.31x31 | VdWContact |
| THR 5 | NTc.Cm25 | ASP 297 | 7.32x31 | Hydrophobic |
| THR 5 | NTc.Cm25 | ASP 297 | 7.32x31 | VdWContact |
| ASN 6 | NTc.Cm24 | HIS 202 | - | Hydrophobic |
| ASN 6 | NTc.Cm24 | HIS 202 | - | VdWContact |
| LYS 7 | NTc.Cm23 | GLN 45 | 1.24x24 | Hydrophobic |
| LYS 7 | NTc.Cm23 | GLN 45 | 1.24x24 | VdWContact |
| LYS 7 | NTc.Cm23 | GLU 293 | 7.28x27 | Cationic |
| LYS 7 | NTc.Cm23 | GLU 293 | 7.28x27 | HBDonor |
| LYS 7 | NTc.Cm23 | GLU 293 | 7.28x27 | VdWContact |
| LYS 7 | NTc.Cm23 | ASP 297 | 7.32x31 | Cationic |
| LYS 7 | NTc.Cm23 | ASP 297 | 7.32x31 | HBDonor |
| LYS 7 | NTc.Cm23 | ASP 297 | 7.32x31 | VdWContact |
| GLU 8 | NTc.Cm22 | GLN 45 | 1.24x24 | HBAcceptor |
| GLU 8 | NTc.Cm22 | GLN 45 | 1.24x24 | VdWContact |
| GLU 8 | NTc.Cm22 | ARG 197 | - | Anionic |
| GLU 8 | NTc.Cm22 | ARG 197 | - | HBAcceptor |
| GLU 8 | NTc.Cm22 | ARG 197 | - | VdWContact |
| GLU 8 | NTc.Cm22 | LEU 198 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | PRO 42 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | PRO 42 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 43 | - | VdWContact |
| LEU 9 | NTc.Cm21 | PRO 44 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | PRO 44 | - | VdWContact |
| LEU 9 | NTc.Cm21 | ARG 197 | - | VdWContact |
| CYS 10 | NTc.Cm20 | CYS 43 | - | HBAcceptor |
| CYS 10 | NTc.Cm20 | CYS 43 | - | HBDonor |
| CYS 10 | NTc.Cm20 | CYS 43 | - | VdWContact |
| LEU 12 | NTc.Cm18 | CYS 43 | - | VdWContact |
| LEU 12 | NTc.Cm18 | ARG 288 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | ARG 288 | - | VdWContact |
| LEU 12 | NTc.Cm18 | ASN 289 | 7.24x23 | VdWContact |
| VAL 13 | NTc.Cm17 | SER 40 | - | VdWContact |
| ILE 19 | NTc.Cm11 | TYR 29 | - | VdWContact |
| PRO 20 | NTc.Cm10 | TYR 29 | - | Hydrophobic |
| PRO 20 | NTc.Cm10 | TYR 29 | - | VdWContact |
| LYS 22 | NTc.Cm8 | TYR 27 | - | HBDonor |
| LYS 22 | NTc.Cm8 | TYR 27 | - | VdWContact |
| PHE 23 | NTc.Cm7 | TYR 29 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | TYR 29 | - | PiStacking |
| PHE 23 | NTc.Cm7 | TYR 29 | - | VdWContact |
| SER 28 | NTc.Cm2 | ARG 197 | - | HBAcceptor |
| SER 28 | NTc.Cm2 | ARG 197 | - | VdWContact |
| SER 31 | CX.5 | ASP 195 | - | VdWContact |
| PRO 32 | cxb1.1 | GLN 204 | 45.51x51 | VdWContact |
| PRO 32 | cxb1.1 | ARG 212 | 5.35x36 | HBAcceptor |
| PRO 32 | cxb1.1 | ARG 212 | 5.35x36 | VdWContact |
| GLN 33 | cxb1.2 | GLN 204 | 45.51x51 | HBDonor |
| GLN 33 | cxb1.2 | GLN 204 | 45.51x51 | Hydrophobic |
| GLN 33 | cxb1.2 | GLN 204 | 45.51x51 | VdWContact |
| PRO 35 | cxb1.6 | GLN 209 | 5.32x33 | VdWContact |
| PRO 35 | cxb1.6 | ARG 288 | - | VdWContact |
| PRO 35 | cxb1.6 | GLU 293 | 7.28x27 | VdWContact |
| ILE 40 | cxb1.14 | PRO 42 | - | Hydrophobic |
| ARG 45 | B1.3 | GLU 33 | - | Cationic |
| ARG 45 | B1.3 | GLU 33 | - | HBDonor |
| ARG 45 | B1.3 | GLU 33 | - | VdWContact |
| ARG 47 | B1.5 | GLU 33 | - | Cationic |
| ARG 47 | B1.5 | GLU 33 | - | HBDonor |
| ARG 47 | B1.5 | GLU 33 | - | VdWContact |
| ARG 47 | B1.5 | ASP 35 | - | Cationic |
| ARG 47 | B1.5 | ASP 35 | - | HBDonor |
| ARG 47 | B1.5 | ASP 35 | - | VdWContact |
| GLN 48 | B1.6 | PRO 42 | - | Hydrophobic |
| GLN 48 | B1.6 | ARG 197 | - | HBAcceptor |
| GLN 48 | B1.6 | ARG 197 | - | VdWContact |
| CYS 50 | b1b2.4 | SER 40 | - | HBDonor |
| CYS 50 | b1b2.4 | SER 40 | - | VdWContact |
| CYS 50 | b1b2.4 | PRO 42 | - | VdWContact |
