Predicted complex interactions
CCL21_HUMAN + CXCR3
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 103
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm30 | TRP 109 | 2.60x60 | VdWContact |
| ASP 2 | NTc.Cm29 | ARG 216 | 5.39x40 | Anionic |
| ASP 2 | NTc.Cm29 | ARG 216 | 5.39x40 | VdWContact |
| ASP 2 | NTc.Cm29 | LYS 300 | 7.35x34 | Anionic |
| ASP 2 | NTc.Cm29 | LYS 300 | 7.35x34 | HBAcceptor |
| ASP 2 | NTc.Cm29 | LYS 300 | 7.35x34 | Hydrophobic |
| ASP 2 | NTc.Cm29 | LYS 300 | 7.35x34 | VdWContact |
| ALA 5 | NTc.Cm26 | ASP 297 | 7.32x31 | HBDonor |
| ALA 5 | NTc.Cm26 | ASP 297 | 7.32x31 | VdWContact |
| GLN 6 | NTc.Cm25 | GLN 45 | 1.24x24 | HBAcceptor |
| GLN 6 | NTc.Cm25 | GLN 45 | 1.24x24 | Hydrophobic |
| GLN 6 | NTc.Cm25 | GLN 45 | 1.24x24 | VdWContact |
| GLN 6 | NTc.Cm25 | SER 48 | 1.27x27 | HBDonor |
| GLN 6 | NTc.Cm25 | SER 48 | 1.27x27 | VdWContact |
| GLN 6 | NTc.Cm25 | LEU 49 | 1.28x28 | Hydrophobic |
| GLN 6 | NTc.Cm25 | LEU 49 | 1.28x28 | VdWContact |
| ASP 7 | NTc.Cm24 | PRO 42 | - | Hydrophobic |
| ASP 7 | NTc.Cm24 | PRO 42 | - | VdWContact |
| ASP 7 | NTc.Cm24 | CYS 43 | - | VdWContact |
| ASP 7 | NTc.Cm24 | PRO 44 | - | VdWContact |
| ASP 7 | NTc.Cm24 | GLN 45 | 1.24x24 | Hydrophobic |
| ASP 7 | NTc.Cm24 | GLN 45 | 1.24x24 | VdWContact |
| ASP 7 | NTc.Cm24 | ARG 197 | - | HBAcceptor |
| ASP 7 | NTc.Cm24 | ARG 197 | - | VdWContact |
| CYS 8 | NTc.Cm23 | CYS 43 | - | HBAcceptor |
| CYS 8 | NTc.Cm23 | CYS 43 | - | VdWContact |
| LEU 10 | NTc.Cm21 | CYS 43 | - | VdWContact |
| LEU 10 | NTc.Cm21 | GLU 293 | 7.28x27 | Hydrophobic |
| LYS 11 | NTc.Cm20 | SER 40 | - | HBAcceptor |
| LYS 11 | NTc.Cm20 | SER 40 | - | VdWContact |
| TYR 12 | NTc.Cm19 | SER 40 | - | VdWContact |
| SER 13 | NTc.Cm18 | CYS 38 | - | VdWContact |
| SER 13 | NTc.Cm18 | THR 39 | - | VdWContact |
| SER 13 | NTc.Cm18 | SER 40 | - | VdWContact |
| GLN 14 | NTc.Cm17 | CYS 38 | - | HBDonor |
| GLN 14 | NTc.Cm17 | CYS 38 | - | Hydrophobic |
| GLN 14 | NTc.Cm17 | CYS 38 | - | VdWContact |
| ARG 15 | NTc.Cm16 | TYR 29 | - | Hydrophobic |
| ARG 15 | NTc.Cm16 | GLU 33 | - | Cationic |
| ARG 15 | NTc.Cm16 | GLU 33 | - | HBDonor |
| ARG 15 | NTc.Cm16 | GLU 33 | - | VdWContact |
| ARG 15 | NTc.Cm16 | ASP 35 | - | Cationic |
| ARG 15 | NTc.Cm16 | ASP 35 | - | HBDonor |
| ARG 15 | NTc.Cm16 | ASP 35 | - | VdWContact |
| ARG 15 | NTc.Cm16 | CYS 37 | - | VdWContact |
| ARG 15 | NTc.Cm16 | CYS 38 | - | Cationic |
| ARG 15 | NTc.Cm16 | CYS 38 | - | Hydrophobic |
| ARG 15 | NTc.Cm16 | CYS 38 | - | VdWContact |
| LYS 16 | NTc.Cm15 | TYR 29 | - | VdWContact |
| ILE 17 | NTc.Cm14 | TYR 29 | - | VdWContact |
| PRO 18 | NTc.Cm13 | TYR 29 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | TYR 29 | - | VdWContact |
| LYS 20 | NTc.Cm11 | ASP 28 | - | Cationic |
| LYS 20 | NTc.Cm11 | ASP 28 | - | HBDonor |
| LYS 20 | NTc.Cm11 | ASP 28 | - | VdWContact |
| LYS 20 | NTc.Cm11 | GLY 30 | - | HBDonor |
| VAL 21 | NTc.Cm10 | TYR 27 | - | Hydrophobic |
| VAL 21 | NTc.Cm10 | TYR 27 | - | VdWContact |
| ARG 26 | NTc.Cm5 | ARG 197 | - | HBDonor |
| ARG 26 | NTc.Cm5 | ARG 197 | - | Hydrophobic |
| ARG 26 | NTc.Cm5 | ARG 197 | - | VdWContact |
| PRO 30 | NTc.Cm1 | GLN 209 | 5.32x33 | Hydrophobic |
| SER 31 | CX.1 | GLN 204 | 45.51x51 | HBDonor |
| SER 31 | CX.1 | GLN 204 | 45.51x51 | VdWContact |
| SER 31 | CX.1 | ARG 212 | 5.35x36 | HBAcceptor |
| SER 31 | CX.1 | ARG 212 | 5.35x36 | VdWContact |
| LEU 32 | CX.5 | TYR 205 | 45.52x52 | Hydrophobic |
| LEU 32 | CX.5 | TYR 205 | 45.52x52 | VdWContact |
| LEU 32 | CX.5 | PHE 207 | - | Hydrophobic |
| LEU 32 | CX.5 | ARG 212 | 5.35x36 | HBAcceptor |
| LEU 32 | CX.5 | ARG 212 | 5.35x36 | Hydrophobic |
| LEU 32 | CX.5 | ARG 212 | 5.35x36 | VdWContact |
| LEU 32 | CX.5 | ARG 216 | 5.39x40 | VdWContact |
| CYS 34 | cxb1.2 | ARG 197 | - | Anionic |
| SER 35 | cxb1.5 | GLN 209 | 5.32x33 | HBAcceptor |
| SER 35 | cxb1.5 | GLN 209 | 5.32x33 | VdWContact |
| LEU 40 | cxb1.11 | PRO 42 | - | Hydrophobic |
| LEU 40 | cxb1.11 | ARG 197 | - | VdWContact |
| PRO 43 | cxb1.16 | TYR 27 | - | Hydrophobic |
| PRO 43 | cxb1.16 | TYR 27 | - | VdWContact |
| SER 47 | B1.4 | ASN 22 | - | VdWContact |
| SER 47 | B1.4 | SER 25 | - | HBAcceptor |
| SER 47 | B1.4 | SER 25 | - | VdWContact |
| GLN 48 | B1.5 | SER 25 | - | HBDonor |
| GLN 48 | B1.5 | SER 25 | - | VdWContact |
| GLN 48 | B1.5 | TYR 27 | - | Hydrophobic |
| GLN 48 | B1.5 | TYR 27 | - | VdWContact |
| ALA 49 | B1.6 | TYR 27 | - | HBAcceptor |
| ALA 49 | B1.6 | TYR 27 | - | VdWContact |
| ALA 49 | B1.6 | PRO 41 | - | Hydrophobic |
| GLU 50 | B1.7 | PRO 41 | - | VdWContact |
| GLU 50 | B1.7 | PRO 42 | - | Hydrophobic |
| GLU 50 | B1.7 | PRO 42 | - | VdWContact |
| LEU 51 | b1b2.4 | TYR 27 | - | Hydrophobic |
| LEU 51 | b1b2.4 | TYR 27 | - | VdWContact |
| LEU 51 | b1b2.4 | THR 39 | - | Hydrophobic |
| LEU 51 | b1b2.4 | THR 39 | - | VdWContact |
| CYS 52 | b1b2.6 | SER 40 | - | HBDonor |
| CYS 52 | b1b2.6 | SER 40 | - | VdWContact |
| LYS 75 | B3.3 | HIS 194 | - | Hydrophobic |
| LYS 75 | B3.3 | HIS 194 | - | VdWContact |
| LYS 75 | B3.3 | ASN 199 | - | HBDonor |
| LYS 75 | B3.3 | ASN 199 | - | VdWContact |
