Predicted complex interactions
CCL22_HUMAN + CXCR3
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 92
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | TYR 60 | 1.39x39 | HBDonor |
| GLY 1 | NTc.Cm35 | TYR 60 | 1.39x39 | VdWContact |
| GLY 1 | NTc.Cm35 | TRP 109 | 2.60x60 | VdWContact |
| GLY 1 | NTc.Cm35 | TYR 308 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm34 | TRP 109 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TRP 109 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm34 | GLY 128 | 3.29x29 | VdWContact |
| PRO 2 | NTc.Cm34 | PHE 131 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | LEU 190 | 4.64x65 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 205 | 45.52x52 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 205 | 45.52x52 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 308 | 7.43x42 | VdWContact |
| TYR 3 | NTc.Cm33 | PHE 131 | 3.32x32 | Hydrophobic |
| TYR 3 | NTc.Cm33 | PHE 131 | 3.32x32 | VdWContact |
| TYR 3 | NTc.Cm33 | ASN 132 | 3.33x33 | HBAcceptor |
| TYR 3 | NTc.Cm33 | ASN 132 | 3.33x33 | HBDonor |
| TYR 3 | NTc.Cm33 | ASN 132 | 3.33x33 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 205 | 45.52x52 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 205 | 45.52x52 | VdWContact |
| TYR 3 | NTc.Cm33 | LEU 215 | 5.38x39 | Hydrophobic |
| TYR 3 | NTc.Cm33 | ARG 216 | 5.39x40 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 271 | 6.51x51 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 271 | 6.51x51 | VdWContact |
| GLY 4 | NTc.Cm32 | SER 304 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm31 | ASP 52 | 1.31x31 | VdWContact |
| ALA 5 | NTc.Cm31 | LEU 56 | 1.35x35 | Hydrophobic |
| ASN 6 | NTc.Cm30 | SER 48 | 1.27x27 | VdWContact |
| ASN 6 | NTc.Cm30 | ASP 52 | 1.31x31 | HBDonor |
| ASN 6 | NTc.Cm30 | ASP 52 | 1.31x31 | VdWContact |
| ASN 6 | NTc.Cm30 | ASP 297 | 7.32x31 | HBDonor |
| ASN 6 | NTc.Cm30 | ASP 297 | 7.32x31 | Hydrophobic |
| ASN 6 | NTc.Cm30 | ASP 297 | 7.32x31 | VdWContact |
| ASN 6 | NTc.Cm30 | SER 301 | 7.36x35 | HBDonor |
| ASN 6 | NTc.Cm30 | SER 301 | 7.36x35 | VdWContact |
| MET 7 | NTc.Cm29 | ASP 112 | 2.63x63 | VdWContact |
| MET 7 | NTc.Cm29 | HIS 202 | - | Hydrophobic |
| MET 7 | NTc.Cm29 | HIS 202 | - | VdWContact |
| MET 7 | NTc.Cm29 | CYS 203 | 45.50x50 | VdWContact |
| MET 7 | NTc.Cm29 | GLN 204 | 45.51x51 | Hydrophobic |
| MET 7 | NTc.Cm29 | GLN 204 | 45.51x51 | VdWContact |
| GLU 8 | NTc.Cm28 | GLN 45 | 1.24x24 | VdWContact |
| GLU 8 | NTc.Cm28 | ARG 212 | 5.35x36 | Anionic |
| GLU 8 | NTc.Cm28 | ARG 212 | 5.35x36 | HBAcceptor |
| GLU 8 | NTc.Cm28 | ARG 212 | 5.35x36 | VdWContact |
| ASP 9 | NTc.Cm27 | GLN 45 | 1.24x24 | Hydrophobic |
| ASP 9 | NTc.Cm27 | GLN 45 | 1.24x24 | VdWContact |
| ASP 9 | NTc.Cm27 | SER 48 | 1.27x27 | HBAcceptor |
| ASP 9 | NTc.Cm27 | SER 48 | 1.27x27 | VdWContact |
| ASP 9 | NTc.Cm27 | LEU 49 | 1.28x28 | Hydrophobic |
| ASP 9 | NTc.Cm27 | LEU 49 | 1.28x28 | VdWContact |
| ASP 9 | NTc.Cm27 | ARG 197 | - | HBAcceptor |
| ASP 9 | NTc.Cm27 | ARG 197 | - | VdWContact |
| SER 10 | NTc.Cm26 | GLN 45 | 1.24x24 | HBAcceptor |
| SER 10 | NTc.Cm26 | GLN 45 | 1.24x24 | VdWContact |
| VAL 11 | NTc.Cm25 | PRO 42 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | PRO 42 | - | VdWContact |
| VAL 11 | NTc.Cm25 | GLN 45 | 1.24x24 | Hydrophobic |
| ARG 14 | NTc.Cm22 | CYS 43 | - | Cationic |
| ARG 14 | NTc.Cm22 | CYS 43 | - | VdWContact |
| ARG 14 | NTc.Cm22 | ARG 288 | - | HBDonor |
| ARG 14 | NTc.Cm22 | ARG 288 | - | VdWContact |
| ARG 14 | NTc.Cm22 | ASN 289 | 7.24x23 | HBDonor |
| ARG 14 | NTc.Cm22 | ASN 289 | 7.24x23 | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 290 | 7.25x24 | Cationic |
| ARG 14 | NTc.Cm22 | CYS 290 | 7.25x24 | VdWContact |
| ARG 14 | NTc.Cm22 | GLU 293 | 7.28x27 | Cationic |
| ARG 14 | NTc.Cm22 | GLU 293 | 7.28x27 | HBDonor |
| ARG 14 | NTc.Cm22 | GLU 293 | 7.28x27 | VdWContact |
| LEU 21 | NTc.Cm15 | TYR 29 | - | Hydrophobic |
| LEU 21 | NTc.Cm15 | TYR 29 | - | VdWContact |
| PRO 22 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | TYR 29 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | TYR 29 | - | VdWContact |
| ARG 24 | NTc.Cm12 | SER 25 | - | HBDonor |
| ARG 24 | NTc.Cm12 | SER 25 | - | VdWContact |
| ARG 24 | NTc.Cm12 | SER 26 | - | VdWContact |
| ARG 24 | NTc.Cm12 | TYR 27 | - | HBDonor |
| ARG 24 | NTc.Cm12 | TYR 27 | - | VdWContact |
| VAL 25 | NTc.Cm11 | TYR 29 | - | Hydrophobic |
| VAL 25 | NTc.Cm11 | TYR 29 | - | VdWContact |
| TYR 30 | NTc.Cm6 | ARG 197 | - | Hydrophobic |
| SER 35 | NTc.Cm1 | ARG 212 | 5.35x36 | HBAcceptor |
| SER 35 | NTc.Cm1 | ARG 212 | 5.35x36 | VdWContact |
| PRO 37 | CX.5 | GLN 209 | 5.32x33 | VdWContact |
| PRO 37 | CX.5 | ARG 288 | - | VdWContact |
| VAL 42 | cxb1.7 | PRO 42 | - | Hydrophobic |
| GLU 50 | B1.2 | PRO 41 | - | VdWContact |
| GLU 50 | B1.2 | PRO 42 | - | Hydrophobic |
| GLU 50 | B1.2 | PRO 42 | - | VdWContact |
| ILE 51 | B1.3 | THR 39 | - | Hydrophobic |
| CYS 52 | B1.4 | SER 40 | - | HBDonor |
| CYS 52 | B1.4 | SER 40 | - | VdWContact |
