Predicted complex interactions
CCL25_HUMAN + CXCR3
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 85
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | TRP 109 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm29 | TRP 109 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm29 | LEU 190 | 4.64x65 | VdWContact |
| GLN 1 | NTc.Cm29 | CYS 203 | 45.50x50 | VdWContact |
| VAL 3 | NTc.Cm27 | HIS 202 | - | Hydrophobic |
| VAL 3 | NTc.Cm27 | GLN 204 | 45.51x51 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLN 45 | 1.24x24 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLN 45 | 1.24x24 | VdWContact |
| PHE 4 | NTc.Cm26 | SER 48 | 1.27x27 | VdWContact |
| PHE 4 | NTc.Cm26 | ASP 52 | 1.31x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 52 | 1.31x31 | VdWContact |
| PHE 4 | NTc.Cm26 | ASP 297 | 7.32x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 297 | 7.32x31 | VdWContact |
| PHE 4 | NTc.Cm26 | VAL 298 | 7.33x32 | Hydrophobic |
| PHE 4 | NTc.Cm26 | VAL 298 | 7.33x32 | VdWContact |
| GLU 5 | NTc.Cm25 | GLN 45 | 1.24x24 | VdWContact |
| GLU 5 | NTc.Cm25 | ARG 197 | - | Anionic |
| GLU 5 | NTc.Cm25 | ARG 197 | - | HBAcceptor |
| GLU 5 | NTc.Cm25 | ARG 197 | - | VdWContact |
| GLU 5 | NTc.Cm25 | GLN 204 | 45.51x51 | HBAcceptor |
| GLU 5 | NTc.Cm25 | GLN 204 | 45.51x51 | VdWContact |
| ASP 6 | NTc.Cm24 | PRO 42 | - | VdWContact |
| ASP 6 | NTc.Cm24 | CYS 43 | - | VdWContact |
| ASP 6 | NTc.Cm24 | PRO 44 | - | VdWContact |
| ASP 6 | NTc.Cm24 | GLN 45 | 1.24x24 | HBAcceptor |
| ASP 6 | NTc.Cm24 | GLN 45 | 1.24x24 | Hydrophobic |
| ASP 6 | NTc.Cm24 | GLN 45 | 1.24x24 | VdWContact |
| ASP 6 | NTc.Cm24 | ARG 197 | - | HBAcceptor |
| ASP 6 | NTc.Cm24 | ARG 197 | - | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 43 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 43 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 43 | - | VdWContact |
| LEU 9 | NTc.Cm21 | ASN 289 | 7.24x23 | VdWContact |
| LEU 9 | NTc.Cm21 | GLU 293 | 7.28x27 | Hydrophobic |
| LEU 9 | NTc.Cm21 | GLU 293 | 7.28x27 | VdWContact |
| HIS 12 | NTc.Cm18 | CYS 38 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | CYS 38 | - | VdWContact |
| HIS 12 | NTc.Cm18 | THR 39 | - | HBAcceptor |
| HIS 12 | NTc.Cm18 | THR 39 | - | VdWContact |
| HIS 12 | NTc.Cm18 | SER 40 | - | VdWContact |
| ALA 18 | NTc.Cm12 | TYR 29 | - | Hydrophobic |
| ARG 21 | NTc.Cm9 | TYR 29 | - | HBDonor |
| ARG 21 | NTc.Cm9 | TYR 29 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 29 | - | CationPi |
| ARG 22 | NTc.Cm8 | TYR 29 | - | Hydrophobic |
| ARG 22 | NTc.Cm8 | TYR 29 | - | VdWContact |
| ARG 27 | NTc.Cm3 | GLU 196 | - | VdWContact |
| ARG 27 | NTc.Cm3 | ARG 197 | - | Hydrophobic |
| ARG 27 | NTc.Cm3 | ARG 197 | - | VdWContact |
| ILE 28 | NTc.Cm2 | ARG 197 | - | VdWContact |
| VAL 31 | CX.5 | GLN 209 | 5.32x33 | Hydrophobic |
| SER 32 | cxb1.1 | GLN 204 | 45.51x51 | VdWContact |
| SER 32 | cxb1.1 | TYR 205 | 45.52x52 | VdWContact |
| GLY 33 | cxb1.2 | GLN 204 | 45.51x51 | VdWContact |
| GLY 33 | cxb1.2 | TYR 205 | 45.52x52 | HBDonor |
| GLY 33 | cxb1.2 | TYR 205 | 45.52x52 | VdWContact |
| GLY 33 | cxb1.2 | ARG 212 | 5.35x36 | HBAcceptor |
| GLY 33 | cxb1.2 | ARG 212 | 5.35x36 | VdWContact |
| SER 34 | cxb1.5 | ASP 297 | 7.32x31 | HBDonor |
| SER 34 | cxb1.5 | ASP 297 | 7.32x31 | VdWContact |
| CYS 35 | cxb1.7 | ARG 197 | - | Anionic |
| CYS 35 | cxb1.7 | ARG 197 | - | VdWContact |
| ASN 36 | cxb1.8 | GLN 209 | 5.32x33 | HBAcceptor |
| ASN 36 | cxb1.8 | GLN 209 | 5.32x33 | VdWContact |
| ASN 36 | cxb1.8 | ARG 288 | - | VdWContact |
| PRO 38 | cxb1.11 | GLN 209 | 5.32x33 | VdWContact |
| ILE 41 | cxb1.16 | PRO 42 | - | Hydrophobic |
| ILE 41 | cxb1.16 | ARG 197 | - | VdWContact |
| ARG 47 | B1.6 | ASP 35 | - | Cationic |
| ARG 47 | B1.6 | ASP 35 | - | HBDonor |
| ARG 47 | B1.6 | ASP 35 | - | VdWContact |
| ARG 49 | b1b2.1 | SER 34 | - | HBDonor |
| ARG 49 | b1b2.1 | SER 34 | - | VdWContact |
| ARG 49 | b1b2.1 | ASP 35 | - | Cationic |
| ARG 49 | b1b2.1 | ASP 35 | - | HBDonor |
| ARG 49 | b1b2.1 | ASP 35 | - | VdWContact |
| ARG 49 | b1b2.1 | CYS 37 | - | VdWContact |
| LYS 50 | b1b2.2 | PRO 42 | - | Hydrophobic |
| LYS 50 | b1b2.2 | PRO 42 | - | VdWContact |
| VAL 51 | b1b2.3 | CYS 38 | - | Hydrophobic |
| VAL 51 | b1b2.3 | CYS 38 | - | VdWContact |
| ARG 70 | b2b3.4 | PHE 23 | - | CationPi |
| ARG 70 | b2b3.4 | PHE 23 | - | VdWContact |
| PHE 74 | B3.2 | LEU 20 | - | Hydrophobic |
| LEU 77 | b3h.1 | VAL 16 | - | Hydrophobic |
