Predicted complex interactions
CXCL4_HUMAN + ACKR2
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 78
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 2 | NTc.Cm39 | PRO 189 | - | Hydrophobic |
| ALA 2 | NTc.Cm39 | PRO 189 | - | VdWContact |
| GLU 4 | NTc.Cm37 | LYS 46 | 1.32x32 | Anionic |
| GLU 4 | NTc.Cm37 | LYS 46 | 1.32x32 | HBAcceptor |
| GLU 4 | NTc.Cm37 | LYS 46 | 1.32x32 | VdWContact |
| ASP 5 | NTc.Cm36 | ASN 188 | - | HBAcceptor |
| ASP 5 | NTc.Cm36 | ASN 188 | - | VdWContact |
| ASP 5 | NTc.Cm36 | ASN 194 | - | VdWContact |
| LEU 8 | NTc.Cm33 | LYS 38 | 1.24x24 | Hydrophobic |
| LEU 8 | NTc.Cm33 | LYS 38 | 1.24x24 | VdWContact |
| LEU 8 | NTc.Cm33 | VAL 41 | 1.27x27 | Hydrophobic |
| LEU 8 | NTc.Cm33 | VAL 42 | 1.28x28 | Hydrophobic |
| LEU 8 | NTc.Cm33 | VAL 42 | 1.28x28 | VdWContact |
| GLN 9 | NTc.Cm32 | LYS 38 | 1.24x24 | HBAcceptor |
| GLN 9 | NTc.Cm32 | LYS 38 | 1.24x24 | Hydrophobic |
| GLN 9 | NTc.Cm32 | LYS 38 | 1.24x24 | VdWContact |
| GLN 9 | NTc.Cm32 | HIS 273 | 6.58x58 | HBDonor |
| GLN 9 | NTc.Cm32 | HIS 273 | 6.58x58 | Hydrophobic |
| GLN 9 | NTc.Cm32 | HIS 273 | 6.58x58 | VdWContact |
| GLN 9 | NTc.Cm32 | SER 287 | 7.28x27 | HBAcceptor |
| GLN 9 | NTc.Cm32 | SER 287 | 7.28x27 | HBDonor |
| GLN 9 | NTc.Cm32 | SER 287 | 7.28x27 | VdWContact |
| GLN 9 | NTc.Cm32 | ASP 291 | 7.32x31 | VdWContact |
| CYS 10 | NTc.Cm31 | LYS 38 | 1.24x24 | VdWContact |
| LEU 11 | NTc.Cm30 | LEU 35 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | CYS 36 | - | HBAcceptor |
| LEU 11 | NTc.Cm30 | CYS 36 | - | VdWContact |
| VAL 13 | NTc.Cm28 | CYS 36 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | LEU 276 | 6.61x61 | Hydrophobic |
| LYS 14 | NTc.Cm27 | ALA 32 | - | Hydrophobic |
| LYS 14 | NTc.Cm27 | ALA 32 | - | VdWContact |
| LYS 14 | NTc.Cm27 | PHE 33 | - | Hydrophobic |
| LYS 14 | NTc.Cm27 | GLY 282 | - | VdWContact |
| THR 16 | NTc.Cm25 | LEU 28 | - | Hydrophobic |
| THR 16 | NTc.Cm25 | PHE 33 | - | Hydrophobic |
| THR 16 | NTc.Cm25 | PHE 33 | - | VdWContact |
| GLN 18 | NTc.Cm23 | TYR 24 | - | HBAcceptor |
| GLN 18 | NTc.Cm23 | TYR 24 | - | VdWContact |
| VAL 19 | NTc.Cm22 | TYR 24 | - | VdWContact |
| VAL 19 | NTc.Cm22 | LEU 28 | - | Hydrophobic |
| VAL 19 | NTc.Cm22 | LEU 28 | - | VdWContact |
| ARG 20 | NTc.Cm21 | TYR 24 | - | CationPi |
| ARG 20 | NTc.Cm21 | TYR 24 | - | HBDonor |
| ARG 20 | NTc.Cm21 | TYR 24 | - | Hydrophobic |
| ARG 20 | NTc.Cm21 | TYR 24 | - | VdWContact |
| HIS 23 | NTc.Cm18 | SER 21 | - | VdWContact |
| HIS 23 | NTc.Cm18 | TYR 24 | - | Hydrophobic |
| HIS 23 | NTc.Cm18 | TYR 25 | - | HBDonor |
| HIS 23 | NTc.Cm18 | TYR 25 | - | Hydrophobic |
| HIS 23 | NTc.Cm18 | TYR 25 | - | VdWContact |
| PRO 34 | NTc.Cm7 | HIS 196 | 45.51x51 | Hydrophobic |
| PRO 34 | NTc.Cm7 | HIS 196 | 45.51x51 | VdWContact |
| PRO 34 | NTc.Cm7 | LYS 207 | 5.35x36 | HBAcceptor |
| PRO 34 | NTc.Cm7 | LYS 207 | 5.35x36 | VdWContact |
| HIS 35 | NTc.Cm6 | LYS 207 | 5.35x36 | VdWContact |
| PRO 37 | NTc.Cm4 | GLY 203 | 5.31x32 | VdWContact |
| PRO 37 | NTc.Cm4 | THR 204 | 5.32x33 | Hydrophobic |
| PRO 37 | NTc.Cm4 | THR 204 | 5.32x33 | VdWContact |
| PRO 37 | NTc.Cm4 | LYS 207 | 5.35x36 | Hydrophobic |
| PRO 37 | NTc.Cm4 | LYS 207 | 5.35x36 | VdWContact |
| THR 38 | NTc.Cm3 | THR 204 | 5.32x33 | Hydrophobic |
| ILE 42 | CX.4 | LEU 35 | - | Hydrophobic |
| ILE 42 | CX.4 | LEU 35 | - | VdWContact |
| LEU 45 | cxb1.2 | TYR 25 | - | Hydrophobic |
| LEU 45 | cxb1.2 | LEU 28 | - | Hydrophobic |
| LYS 46 | cxb1.5 | TYR 25 | - | VdWContact |
| ARG 49 | cxb1.10 | ASP 29 | - | Cationic |
| ARG 49 | cxb1.10 | ASP 29 | - | HBDonor |
| ARG 49 | cxb1.10 | ASP 29 | - | VdWContact |
| LYS 50 | cxb1.11 | LEU 35 | - | HBAcceptor |
| LYS 50 | cxb1.11 | LEU 35 | - | Hydrophobic |
| LYS 50 | cxb1.11 | LEU 35 | - | VdWContact |
| ILE 51 | cxb1.14 | LEU 28 | - | Hydrophobic |
| ILE 51 | cxb1.14 | PHE 33 | - | VdWContact |
| ILE 51 | cxb1.14 | MET 34 | - | Hydrophobic |
| CYS 52 | cxb1.15 | PHE 33 | - | HBDonor |
| CYS 52 | cxb1.15 | PHE 33 | - | VdWContact |
| CYS 52 | cxb1.15 | LEU 35 | - | VdWContact |
