Predicted complex interactions
CCL8_HUMAN + CXCR3
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 68
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | PHE 131 | 3.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 271 | 6.51x51 | HBDonor |
| GLN 1 | NTc.Cm33 | TYR 271 | 6.51x51 | VdWContact |
| GLN 1 | NTc.Cm33 | SER 304 | 7.39x38 | HBAcceptor |
| GLN 1 | NTc.Cm33 | SER 304 | 7.39x38 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 308 | 7.43x42 | HBDonor |
| GLN 1 | NTc.Cm33 | TYR 308 | 7.43x42 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 308 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm32 | TRP 109 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TRP 109 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | LEU 190 | 4.64x65 | Hydrophobic |
| PRO 2 | NTc.Cm32 | LEU 190 | 4.64x65 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 205 | 45.52x52 | Hydrophobic |
| ASP 3 | NTc.Cm31 | TYR 205 | 45.52x52 | VdWContact |
| ASP 3 | NTc.Cm31 | ARG 212 | 5.35x36 | Anionic |
| ASP 3 | NTc.Cm31 | ARG 216 | 5.39x40 | Anionic |
| ASP 3 | NTc.Cm31 | ARG 216 | 5.39x40 | HBAcceptor |
| ASP 3 | NTc.Cm31 | ARG 216 | 5.39x40 | VdWContact |
| SER 4 | NTc.Cm30 | SER 301 | 7.36x35 | VdWContact |
| VAL 5 | NTc.Cm29 | ASP 112 | 2.63x63 | VdWContact |
| VAL 5 | NTc.Cm29 | HIS 202 | - | Hydrophobic |
| SER 6 | NTc.Cm28 | SER 48 | 1.27x27 | VdWContact |
| SER 6 | NTc.Cm28 | ASP 52 | 1.31x31 | HBDonor |
| SER 6 | NTc.Cm28 | ASP 52 | 1.31x31 | VdWContact |
| ILE 7 | NTc.Cm27 | LEU 198 | - | Hydrophobic |
| ILE 7 | NTc.Cm27 | HIS 202 | - | Hydrophobic |
| ILE 7 | NTc.Cm27 | GLN 204 | 45.51x51 | Hydrophobic |
| ILE 7 | NTc.Cm27 | GLN 204 | 45.51x51 | VdWContact |
| PRO 8 | NTc.Cm26 | GLN 45 | 1.24x24 | Hydrophobic |
| PRO 8 | NTc.Cm26 | GLN 45 | 1.24x24 | VdWContact |
| PRO 8 | NTc.Cm26 | LEU 49 | 1.28x28 | Hydrophobic |
| PRO 8 | NTc.Cm26 | LEU 49 | 1.28x28 | VdWContact |
| PRO 8 | NTc.Cm26 | LEU 198 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | LEU 198 | - | VdWContact |
| ILE 9 | NTc.Cm25 | ASP 195 | - | VdWContact |
| THR 10 | NTc.Cm24 | PRO 42 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | PRO 42 | - | VdWContact |
| THR 10 | NTc.Cm24 | CYS 43 | - | VdWContact |
| THR 10 | NTc.Cm24 | ARG 197 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 43 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 43 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 43 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 43 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ARG 288 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | ARG 288 | - | VdWContact |
| PHE 13 | NTc.Cm21 | GLU 293 | 7.28x27 | Hydrophobic |
| PHE 13 | NTc.Cm21 | GLU 293 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | SER 40 | - | VdWContact |
| ARG 18 | NTc.Cm16 | GLU 33 | - | Cationic |
| ARG 18 | NTc.Cm16 | GLU 33 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TYR 29 | - | VdWContact |
| ASN 33 | NTc.Cm1 | ASP 195 | - | VdWContact |
| GLN 35 | CX.5 | GLN 204 | 45.51x51 | HBDonor |
| GLN 35 | CX.5 | GLN 204 | 45.51x51 | VdWContact |
| GLN 35 | CX.5 | ARG 212 | 5.35x36 | HBAcceptor |
| GLN 35 | CX.5 | ARG 212 | 5.35x36 | VdWContact |
| ILE 42 | cxb1.10 | PRO 42 | - | Hydrophobic |
| ARG 47 | B1.1 | GLU 31 | - | Cationic |
| ARG 47 | B1.1 | ASP 35 | - | Cationic |
| LYS 49 | B1.3 | ASP 35 | - | Cationic |
| LYS 49 | B1.3 | ASP 35 | - | HBDonor |
| LYS 49 | B1.3 | ASP 35 | - | VdWContact |
| GLU 50 | B1.4 | PRO 41 | - | VdWContact |
| GLU 50 | B1.4 | PRO 42 | - | Hydrophobic |
| GLU 50 | B1.4 | PRO 42 | - | VdWContact |
| CYS 52 | B1.6 | SER 40 | - | HBDonor |
| CYS 52 | B1.6 | SER 40 | - | VdWContact |
| CYS 52 | B1.6 | PRO 42 | - | VdWContact |
