Predicted complex interactions
CXCL10_HUMAN + CXCR3
SUMMARY
- Chemokine
- CXCL10_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 154
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm29 | TRP 109 | 2.60x60 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TRP 109 | 2.60x60 | VdWContact |
| VAL 1 | NTc.Cm29 | LEU 190 | 4.64x65 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TYR 205 | 45.52x52 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TYR 205 | 45.52x52 | VdWContact |
| PRO 2 | NTc.Cm28 | PHE 131 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm28 | PHE 131 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm28 | TYR 271 | 6.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm28 | TYR 271 | 6.51x51 | VdWContact |
| PRO 2 | NTc.Cm28 | SER 304 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | TYR 308 | 7.43x42 | Hydrophobic |
| LEU 3 | NTc.Cm27 | LEU 56 | 1.35x35 | Hydrophobic |
| LEU 3 | NTc.Cm27 | TYR 60 | 1.39x39 | Hydrophobic |
| LEU 3 | NTc.Cm27 | TYR 60 | 1.39x39 | VdWContact |
| LEU 3 | NTc.Cm27 | TRP 109 | 2.60x60 | Hydrophobic |
| LEU 3 | NTc.Cm27 | TRP 109 | 2.60x60 | VdWContact |
| LEU 3 | NTc.Cm27 | TYR 308 | 7.43x42 | Hydrophobic |
| LEU 3 | NTc.Cm27 | TYR 308 | 7.43x42 | VdWContact |
| SER 4 | NTc.Cm26 | CYS 203 | 45.50x50 | VdWContact |
| SER 4 | NTc.Cm26 | GLN 204 | 45.51x51 | VdWContact |
| ARG 5 | NTc.Cm25 | LEU 49 | 1.28x28 | HBDonor |
| ARG 5 | NTc.Cm25 | LEU 49 | 1.28x28 | VdWContact |
| ARG 5 | NTc.Cm25 | ASP 52 | 1.31x31 | Cationic |
| ARG 5 | NTc.Cm25 | ASP 52 | 1.31x31 | HBDonor |
| ARG 5 | NTc.Cm25 | ASP 52 | 1.31x31 | VdWContact |
| ARG 5 | NTc.Cm25 | LEU 198 | - | Hydrophobic |
| ARG 5 | NTc.Cm25 | HIS 202 | - | VdWContact |
| THR 6 | NTc.Cm24 | LYS 300 | 7.35x34 | HBAcceptor |
| THR 6 | NTc.Cm24 | LYS 300 | 7.35x34 | VdWContact |
| VAL 7 | NTc.Cm23 | ASP 195 | - | Hydrophobic |
| VAL 7 | NTc.Cm23 | ASP 195 | - | VdWContact |
| VAL 7 | NTc.Cm23 | ARG 197 | - | Hydrophobic |
| VAL 7 | NTc.Cm23 | LEU 198 | - | Hydrophobic |
| VAL 7 | NTc.Cm23 | LEU 198 | - | VdWContact |
| VAL 7 | NTc.Cm23 | GLN 204 | 45.51x51 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 278 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 278 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 278 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 282 | 6.62x62 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 297 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 297 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 297 | 7.32x31 | VdWContact |
| CYS 9 | NTc.Cm21 | ARG 288 | - | HBAcceptor |
| CYS 9 | NTc.Cm21 | ARG 288 | - | VdWContact |
| THR 10 | NTc.Cm20 | CYS 43 | - | HBAcceptor |
| THR 10 | NTc.Cm20 | CYS 43 | - | VdWContact |
| THR 10 | NTc.Cm20 | ARG 197 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 43 | - | VdWContact |
| ILE 12 | NTc.Cm18 | ARG 288 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | ARG 288 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 290 | 7.25x24 | VdWContact |
| SER 15 | NTc.Cm15 | SER 40 | - | VdWContact |
| PRO 18 | NTc.Cm12 | TYR 27 | - | Hydrophobic |
| PRO 18 | NTc.Cm12 | TYR 29 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 29 | - | HBAcceptor |
| VAL 19 | NTc.Cm11 | TYR 29 | - | VdWContact |
| ASN 20 | NTc.Cm10 | TYR 29 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | LEU 20 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | LEU 20 | - | VdWContact |
| PRO 21 | NTc.Cm9 | TYR 29 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | TYR 29 | - | VdWContact |
| LEU 24 | NTc.Cm6 | VAL 16 | - | Hydrophobic |
| LEU 24 | NTc.Cm6 | VAL 16 | - | VdWContact |
| GLU 25 | NTc.Cm5 | ASP 13 | - | HBAcceptor |
| GLU 25 | NTc.Cm5 | ASP 13 | - | VdWContact |
| LYS 26 | NTc.Cm4 | VAL 10 | - | Hydrophobic |
| LYS 26 | NTc.Cm4 | LEU 11 | - | VdWContact |
| LEU 27 | NTc.Cm3 | LEU 11 | - | HBAcceptor |
| LEU 27 | NTc.Cm3 | LEU 11 | - | HBDonor |
| LEU 27 | NTc.Cm3 | LEU 11 | - | Hydrophobic |
| LEU 27 | NTc.Cm3 | LEU 11 | - | VdWContact |
| LEU 27 | NTc.Cm3 | VAL 16 | - | Hydrophobic |
| GLU 28 | NTc.Cm2 | HIS 8 | - | HBAcceptor |
| GLU 28 | NTc.Cm2 | HIS 8 | - | Hydrophobic |
| GLU 28 | NTc.Cm2 | HIS 8 | - | VdWContact |
| GLU 28 | NTc.Cm2 | GLN 9 | - | VdWContact |
| GLU 28 | NTc.Cm2 | VAL 10 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | VAL 5 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | VAL 5 | - | VdWContact |
| ILE 29 | NTc.Cm1 | HIS 8 | - | VdWContact |
| ILE 29 | NTc.Cm1 | GLN 9 | - | HBAcceptor |
| ILE 29 | NTc.Cm1 | GLN 9 | - | HBDonor |
| ILE 29 | NTc.Cm1 | GLN 9 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | GLN 9 | - | VdWContact |
| ILE 29 | NTc.Cm1 | LEU 11 | - | Hydrophobic |
| ILE 30 | CX.1 | HIS 8 | - | Hydrophobic |
| ILE 30 | CX.1 | GLU 196 | - | Hydrophobic |
| ILE 30 | CX.1 | ARG 197 | - | Hydrophobic |
| ILE 30 | CX.1 | ARG 197 | - | VdWContact |
| PRO 31 | CX.4 | VAL 5 | - | Hydrophobic |
| PRO 31 | CX.4 | VAL 5 | - | VdWContact |
| PRO 31 | CX.4 | ARG 197 | - | HBAcceptor |
| PRO 31 | CX.4 | ARG 197 | - | VdWContact |
| GLN 34 | cxb1.2 | TYR 205 | 45.52x52 | HBDonor |
| GLN 34 | cxb1.2 | TYR 205 | 45.52x52 | VdWContact |
| GLN 34 | cxb1.2 | ASN 206 | - | VdWContact |
| GLN 34 | cxb1.2 | PHE 207 | - | HBAcceptor |
| GLN 34 | cxb1.2 | PHE 207 | - | VdWContact |
| PHE 35 | cxb1.5 | GLN 204 | 45.51x51 | Hydrophobic |
| PHE 35 | cxb1.5 | GLN 204 | 45.51x51 | VdWContact |
| PHE 35 | cxb1.5 | ARG 212 | 5.35x36 | VdWContact |
| CYS 36 | cxb1.6 | ARG 197 | - | Anionic |
| CYS 36 | cxb1.6 | ARG 197 | - | VdWContact |
| VAL 39 | cxb1.10 | VAL 5 | - | Hydrophobic |
| GLU 40 | cxb1.11 | ARG 197 | - | Anionic |
| GLU 40 | cxb1.11 | ARG 197 | - | HBAcceptor |
| GLU 40 | cxb1.11 | ARG 197 | - | VdWContact |
| ILE 42 | cxb1.15 | PRO 42 | - | Hydrophobic |
| LYS 46 | B1.3 | ASP 13 | - | Cationic |
| LYS 46 | B1.3 | ASP 13 | - | HBDonor |
| LYS 46 | B1.3 | ASP 13 | - | VdWContact |
| LYS 47 | B1.4 | GLU 33 | - | Cationic |
| LYS 47 | B1.4 | GLU 33 | - | VdWContact |
| LYS 47 | B1.4 | ASP 35 | - | Cationic |
| LYS 47 | B1.4 | ASP 35 | - | HBDonor |
| LYS 47 | B1.4 | ASP 35 | - | VdWContact |
| GLU 50 | B1.7 | THR 39 | - | VdWContact |
| LYS 51 | b1b2.4 | PRO 41 | - | VdWContact |
| LYS 51 | b1b2.4 | PRO 42 | - | Hydrophobic |
| ARG 52 | b1b2.6 | ASP 35 | - | Cationic |
| ARG 52 | b1b2.6 | ASP 35 | - | HBDonor |
| ARG 52 | b1b2.6 | ASP 35 | - | VdWContact |
| CYS 53 | b1b2.7 | SER 40 | - | HBAcceptor |
| CYS 53 | b1b2.7 | SER 40 | - | HBDonor |
| CYS 53 | b1b2.7 | SER 40 | - | VdWContact |
| LYS 59 | b1b2.14 | TYR 27 | - | VdWContact |
| ALA 60 | b1b2.16 | TYR 27 | - | Hydrophobic |
| ALA 60 | b1b2.16 | TYR 27 | - | VdWContact |
| LYS 62 | B2.2 | LEU 3 | - | Hydrophobic |
| LYS 62 | B2.2 | LEU 3 | - | VdWContact |
| ASN 63 | B2.3 | PHE 23 | - | Hydrophobic |
| ASN 63 | B2.3 | PHE 23 | - | VdWContact |
| LEU 64 | B2.4 | LEU 11 | - | Hydrophobic |
| LEU 64 | B2.4 | LEU 11 | - | VdWContact |
| LEU 64 | B2.4 | VAL 16 | - | Hydrophobic |
| LEU 64 | B2.4 | LEU 19 | - | Hydrophobic |
| LEU 64 | B2.4 | LEU 20 | - | Hydrophobic |
| LEU 65 | B2.5 | LEU 3 | - | Hydrophobic |
| LEU 65 | B2.5 | LEU 3 | - | VdWContact |
| LEU 65 | B2.5 | VAL 5 | - | Hydrophobic |
| LYS 66 | B2.6 | LEU 3 | - | Hydrophobic |
| ALA 67 | b2b3.2 | LEU 19 | - | Hydrophobic |
| ALA 67 | b2b3.2 | LEU 19 | - | VdWContact |
| ALA 67 | b2b3.2 | PHE 23 | - | Hydrophobic |
| ALA 67 | b2b3.2 | PHE 23 | - | VdWContact |
| VAL 68 | b2b3.3 | GLN 9 | - | VdWContact |
| VAL 68 | b2b3.3 | LEU 11 | - | Hydrophobic |
| VAL 68 | b2b3.3 | LEU 11 | - | VdWContact |
| VAL 68 | b2b3.3 | LEU 19 | - | Hydrophobic |
| VAL 68 | b2b3.3 | LEU 19 | - | VdWContact |
| GLU 71 | b2b3.12 | LEU 19 | - | Hydrophobic |
| ARG 72 | B3.1 | ASP 7 | - | Cationic |
| ARG 72 | B3.1 | ASP 7 | - | HBDonor |
| ARG 72 | B3.1 | ASP 7 | - | VdWContact |
