Predicted complex interactions
CXCL5_HUMAN + ACKR2
SUMMARY
- Chemokine
- CXCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 91
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm48 | SER 121 | 3.29x29 | VdWContact |
| ALA 1 | NTc.Cm48 | ASP 179 | 4.60x61 | Hydrophobic |
| ALA 1 | NTc.Cm48 | ASP 179 | 4.60x61 | VdWContact |
| ALA 1 | NTc.Cm48 | VAL 183 | 4.64x65 | Hydrophobic |
| ALA 1 | NTc.Cm48 | VAL 183 | 4.64x65 | VdWContact |
| GLY 2 | NTc.Cm47 | TRP 102 | 2.60x60 | VdWContact |
| PRO 3 | NTc.Cm46 | TYR 53 | 1.39x39 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TYR 53 | 1.39x39 | VdWContact |
| PRO 3 | NTc.Cm46 | TRP 102 | 2.60x60 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TRP 102 | 2.60x60 | VdWContact |
| PRO 3 | NTc.Cm46 | TYR 124 | 3.32x32 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TYR 124 | 3.32x32 | VdWContact |
| PRO 3 | NTc.Cm46 | GLU 298 | 7.39x38 | VdWContact |
| PRO 3 | NTc.Cm46 | PHE 302 | 7.43x42 | Hydrophobic |
| ALA 4 | NTc.Cm45 | LEU 270 | 6.55x55 | Hydrophobic |
| ALA 4 | NTc.Cm45 | LEU 294 | 7.35x34 | Hydrophobic |
| ALA 4 | NTc.Cm45 | GLU 298 | 7.39x38 | HBDonor |
| ALA 4 | NTc.Cm45 | GLU 298 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm44 | LEU 49 | 1.35x35 | Hydrophobic |
| ALA 5 | NTc.Cm44 | LEU 294 | 7.35x34 | Hydrophobic |
| ALA 5 | NTc.Cm44 | GLN 295 | 7.36x35 | Hydrophobic |
| ALA 5 | NTc.Cm44 | GLN 295 | 7.36x35 | VdWContact |
| ALA 5 | NTc.Cm44 | GLU 298 | 7.39x38 | HBDonor |
| ALA 5 | NTc.Cm44 | GLU 298 | 7.39x38 | VdWContact |
| ALA 6 | NTc.Cm43 | TRP 102 | 2.60x60 | Hydrophobic |
| ALA 6 | NTc.Cm43 | VAL 106 | 2.64x64 | Hydrophobic |
| ALA 6 | NTc.Cm43 | VAL 106 | 2.64x64 | VdWContact |
| VAL 7 | NTc.Cm42 | TRP 102 | 2.60x60 | Hydrophobic |
| VAL 7 | NTc.Cm42 | HIS 196 | 45.51x51 | Hydrophobic |
| LEU 8 | NTc.Cm41 | ARG 211 | 5.39x40 | VdWContact |
| LEU 8 | NTc.Cm41 | HIS 273 | 6.58x58 | Hydrophobic |
| LEU 8 | NTc.Cm41 | LEU 294 | 7.35x34 | Hydrophobic |
| LEU 8 | NTc.Cm41 | LEU 294 | 7.35x34 | VdWContact |
| ARG 9 | NTc.Cm40 | LYS 46 | 1.32x32 | VdWContact |
| ARG 9 | NTc.Cm40 | VAL 106 | 2.64x64 | HBDonor |
| ARG 9 | NTc.Cm40 | VAL 106 | 2.64x64 | VdWContact |
| ARG 9 | NTc.Cm40 | TRP 108 | 2.66x66 | HBDonor |
| ARG 9 | NTc.Cm40 | TRP 108 | 2.66x66 | VdWContact |
| GLU 10 | NTc.Cm39 | ASN 194 | - | VdWContact |
| GLU 10 | NTc.Cm39 | HIS 196 | 45.51x51 | HBAcceptor |
| GLU 10 | NTc.Cm39 | HIS 196 | 45.51x51 | Hydrophobic |
| GLU 10 | NTc.Cm39 | HIS 196 | 45.51x51 | VdWContact |
| ARG 12 | NTc.Cm37 | LYS 38 | 1.24x24 | VdWContact |
| ARG 12 | NTc.Cm37 | HIS 273 | 6.58x58 | VdWContact |
| ARG 12 | NTc.Cm37 | LEU 276 | 6.61x61 | VdWContact |
| ARG 12 | NTc.Cm37 | SER 287 | 7.28x27 | HBDonor |
| ARG 12 | NTc.Cm37 | SER 287 | 7.28x27 | VdWContact |
| ARG 12 | NTc.Cm37 | ASP 291 | 7.32x31 | Cationic |
| ARG 12 | NTc.Cm37 | ASP 291 | 7.32x31 | HBDonor |
| ARG 12 | NTc.Cm37 | ASP 291 | 7.32x31 | VdWContact |
| VAL 14 | NTc.Cm35 | LEU 35 | - | Hydrophobic |
| VAL 14 | NTc.Cm35 | LEU 35 | - | VdWContact |
| VAL 14 | NTc.Cm35 | CYS 36 | - | HBAcceptor |
| VAL 14 | NTc.Cm35 | CYS 36 | - | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 36 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | CYS 284 | 7.25x24 | Hydrophobic |
| GLN 17 | NTc.Cm32 | PHE 33 | - | Hydrophobic |
| GLN 17 | NTc.Cm32 | PHE 33 | - | VdWContact |
| THR 18 | NTc.Cm31 | PHE 33 | - | VdWContact |
| THR 19 | NTc.Cm30 | ALA 32 | - | VdWContact |
| THR 19 | NTc.Cm30 | PHE 33 | - | HBAcceptor |
| THR 19 | NTc.Cm30 | PHE 33 | - | VdWContact |
| GLN 20 | NTc.Cm29 | GLU 30 | - | VdWContact |
| HIS 23 | NTc.Cm26 | TYR 24 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | TYR 24 | - | PiStacking |
| HIS 23 | NTc.Cm26 | TYR 24 | - | VdWContact |
| LYS 25 | NTc.Cm24 | TYR 24 | - | HBDonor |
| LYS 25 | NTc.Cm24 | TYR 24 | - | Hydrophobic |
| LYS 25 | NTc.Cm24 | TYR 24 | - | VdWContact |
| MET 26 | NTc.Cm23 | LEU 28 | - | Hydrophobic |
| MET 26 | NTc.Cm23 | LEU 28 | - | VdWContact |
| PRO 37 | NTc.Cm12 | HIS 186 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | HIS 196 | 45.51x51 | Hydrophobic |
| PRO 37 | NTc.Cm12 | HIS 196 | 45.51x51 | VdWContact |
| PRO 37 | NTc.Cm12 | ASP 198 | - | Hydrophobic |
| SER 40 | NTc.Cm9 | THR 204 | 5.32x33 | VdWContact |
| LYS 41 | NTc.Cm8 | GLN 279 | 6.64x64 | VdWContact |
| VAL 45 | NTc.Cm4 | LEU 35 | - | Hydrophobic |
| VAL 45 | NTc.Cm4 | LEU 35 | - | VdWContact |
| LYS 52 | cxb1.1 | MET 34 | - | Hydrophobic |
| GLU 53 | cxb1.2 | MET 34 | - | VdWContact |
| GLU 53 | cxb1.2 | LEU 35 | - | Hydrophobic |
| GLU 53 | cxb1.2 | LEU 35 | - | VdWContact |
| GLU 53 | cxb1.2 | ARG 37 | - | Anionic |
| GLU 53 | cxb1.2 | ARG 37 | - | HBAcceptor |
| GLU 53 | cxb1.2 | ARG 37 | - | VdWContact |
| ILE 54 | cxb1.5 | ALA 32 | - | Hydrophobic |
| ILE 54 | cxb1.5 | ALA 32 | - | VdWContact |
| ILE 54 | cxb1.5 | MET 34 | - | VdWContact |
| CYS 55 | cxb1.6 | PHE 33 | - | HBDonor |
| CYS 55 | cxb1.6 | PHE 33 | - | VdWContact |
