Predicted complex interactions
CXCL13_HUMAN + CXCR3
SUMMARY
- Chemokine
- CXCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 157
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm32 | TYR 60 | 1.39x39 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TYR 60 | 1.39x39 | VdWContact |
| VAL 1 | NTc.Cm32 | TRP 109 | 2.60x60 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TRP 109 | 2.60x60 | VdWContact |
| VAL 1 | NTc.Cm32 | TYR 308 | 7.43x42 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TYR 308 | 7.43x42 | VdWContact |
| LEU 2 | NTc.Cm31 | TRP 109 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm31 | PHE 131 | 3.32x32 | Hydrophobic |
| LEU 2 | NTc.Cm31 | LEU 190 | 4.64x65 | Hydrophobic |
| LEU 2 | NTc.Cm31 | LEU 190 | 4.64x65 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 205 | 45.52x52 | Hydrophobic |
| GLU 3 | NTc.Cm30 | ARG 216 | 5.39x40 | Anionic |
| GLU 3 | NTc.Cm30 | ARG 216 | 5.39x40 | HBAcceptor |
| GLU 3 | NTc.Cm30 | ARG 216 | 5.39x40 | VdWContact |
| VAL 4 | NTc.Cm29 | ASP 52 | 1.31x31 | Hydrophobic |
| VAL 4 | NTc.Cm29 | ASP 52 | 1.31x31 | VdWContact |
| VAL 4 | NTc.Cm29 | LEU 56 | 1.35x35 | Hydrophobic |
| VAL 4 | NTc.Cm29 | LEU 56 | 1.35x35 | VdWContact |
| TYR 5 | NTc.Cm28 | ASP 112 | 2.63x63 | HBDonor |
| TYR 5 | NTc.Cm28 | ASP 112 | 2.63x63 | VdWContact |
| TYR 5 | NTc.Cm28 | ALA 113 | 2.64x64 | VdWContact |
| TYR 5 | NTc.Cm28 | LEU 198 | - | Hydrophobic |
| TYR 5 | NTc.Cm28 | HIS 202 | - | Hydrophobic |
| TYR 5 | NTc.Cm28 | HIS 202 | - | PiStacking |
| TYR 5 | NTc.Cm28 | HIS 202 | - | VdWContact |
| TYR 6 | NTc.Cm27 | TYR 205 | 45.52x52 | HBAcceptor |
| TYR 6 | NTc.Cm27 | TYR 205 | 45.52x52 | Hydrophobic |
| TYR 6 | NTc.Cm27 | TYR 205 | 45.52x52 | VdWContact |
| TYR 6 | NTc.Cm27 | ARG 212 | 5.35x36 | Hydrophobic |
| TYR 6 | NTc.Cm27 | ARG 212 | 5.35x36 | PiCation |
| TYR 6 | NTc.Cm27 | ARG 212 | 5.35x36 | VdWContact |
| THR 7 | NTc.Cm26 | GLN 45 | 1.24x24 | HBAcceptor |
| THR 7 | NTc.Cm26 | ASP 297 | 7.32x31 | Hydrophobic |
| THR 7 | NTc.Cm26 | ASP 297 | 7.32x31 | VdWContact |
| SER 8 | NTc.Cm25 | GLN 45 | 1.24x24 | HBAcceptor |
| SER 8 | NTc.Cm25 | GLN 45 | 1.24x24 | VdWContact |
| SER 8 | NTc.Cm25 | LEU 198 | - | VdWContact |
| LEU 9 | NTc.Cm24 | ASP 195 | - | VdWContact |
| LEU 9 | NTc.Cm24 | LEU 198 | - | Hydrophobic |
| LEU 9 | NTc.Cm24 | GLN 204 | 45.51x51 | VdWContact |
| ARG 10 | NTc.Cm23 | GLN 45 | 1.24x24 | HBAcceptor |
| ARG 10 | NTc.Cm23 | GLN 45 | 1.24x24 | VdWContact |
| ARG 10 | NTc.Cm23 | ASP 278 | 6.58x58 | Cationic |
| ARG 10 | NTc.Cm23 | ASP 278 | 6.58x58 | HBDonor |
| ARG 10 | NTc.Cm23 | ASP 278 | 6.58x58 | VdWContact |
| ARG 10 | NTc.Cm23 | ASP 282 | 6.62x62 | Cationic |
| ARG 10 | NTc.Cm23 | GLU 293 | 7.28x27 | Cationic |
| ARG 10 | NTc.Cm23 | ASP 297 | 7.32x31 | Cationic |
| ARG 10 | NTc.Cm23 | ASP 297 | 7.32x31 | HBDonor |
| ARG 10 | NTc.Cm23 | ASP 297 | 7.32x31 | VdWContact |
| ARG 10 | NTc.Cm23 | LYS 300 | 7.35x34 | VdWContact |
| CYS 11 | NTc.Cm22 | ARG 288 | - | HBAcceptor |
| CYS 11 | NTc.Cm22 | ARG 288 | - | VdWContact |
| ARG 12 | NTc.Cm21 | PRO 42 | - | Hydrophobic |
| ARG 12 | NTc.Cm21 | PRO 42 | - | VdWContact |
| ARG 12 | NTc.Cm21 | CYS 43 | - | HBAcceptor |
| ARG 12 | NTc.Cm21 | CYS 43 | - | HBDonor |
| ARG 12 | NTc.Cm21 | CYS 43 | - | VdWContact |
| ARG 12 | NTc.Cm21 | GLN 45 | 1.24x24 | Hydrophobic |
| ARG 12 | NTc.Cm21 | GLN 45 | 1.24x24 | VdWContact |
| ARG 12 | NTc.Cm21 | ASP 46 | 1.25x25 | Cationic |
| VAL 14 | NTc.Cm19 | CYS 43 | - | VdWContact |
| VAL 14 | NTc.Cm19 | ARG 288 | - | Hydrophobic |
| GLN 15 | NTc.Cm18 | SER 40 | - | VdWContact |
| VAL 19 | NTc.Cm14 | CYS 38 | - | VdWContact |
| PHE 20 | NTc.Cm13 | TYR 27 | - | Hydrophobic |
| PHE 20 | NTc.Cm13 | TYR 27 | - | PiStacking |
| ARG 23 | NTc.Cm10 | ASP 13 | - | Cationic |
| ARG 23 | NTc.Cm10 | ASP 13 | - | HBDonor |
| ARG 23 | NTc.Cm10 | ASP 13 | - | VdWContact |
| ARG 23 | NTc.Cm10 | VAL 16 | - | VdWContact |
| ARG 23 | NTc.Cm10 | ALA 17 | - | VdWContact |
| ARG 23 | NTc.Cm10 | LEU 20 | - | Hydrophobic |
| ARG 23 | NTc.Cm10 | LEU 20 | - | VdWContact |
| PHE 25 | NTc.Cm8 | ASP 35 | - | Hydrophobic |
| ILE 26 | NTc.Cm7 | ASP 13 | - | VdWContact |
| ILE 26 | NTc.Cm7 | VAL 16 | - | Hydrophobic |
| ILE 26 | NTc.Cm7 | LEU 20 | - | Hydrophobic |
| ARG 28 | NTc.Cm5 | LEU 11 | - | VdWContact |
| ILE 29 | NTc.Cm4 | VAL 10 | - | VdWContact |
| ILE 29 | NTc.Cm4 | LEU 11 | - | HBAcceptor |
| ILE 29 | NTc.Cm4 | LEU 11 | - | HBDonor |
| ILE 29 | NTc.Cm4 | LEU 11 | - | Hydrophobic |
| ILE 29 | NTc.Cm4 | LEU 11 | - | VdWContact |
| ILE 29 | NTc.Cm4 | VAL 16 | - | Hydrophobic |
| GLN 30 | NTc.Cm3 | HIS 8 | - | Hydrophobic |
| GLN 30 | NTc.Cm3 | HIS 8 | - | VdWContact |
| GLN 30 | NTc.Cm3 | GLN 9 | - | VdWContact |
| GLN 30 | NTc.Cm3 | VAL 10 | - | Hydrophobic |
| GLN 30 | NTc.Cm3 | VAL 10 | - | VdWContact |
| ILE 31 | NTc.Cm2 | GLN 9 | - | HBAcceptor |
| ILE 31 | NTc.Cm2 | GLN 9 | - | HBDonor |
| ILE 31 | NTc.Cm2 | GLN 9 | - | Hydrophobic |
| ILE 31 | NTc.Cm2 | GLN 9 | - | VdWContact |
| ILE 31 | NTc.Cm2 | LEU 11 | - | Hydrophobic |
| LEU 32 | NTc.Cm1 | HIS 8 | - | Hydrophobic |
| LEU 32 | NTc.Cm1 | ARG 197 | - | Hydrophobic |
| PRO 33 | CX.1 | SER 6 | - | VdWContact |
| PRO 33 | CX.1 | GLU 196 | - | Hydrophobic |
| PRO 33 | CX.1 | GLU 196 | - | VdWContact |
| PRO 33 | CX.1 | ARG 197 | - | HBAcceptor |
| PRO 33 | CX.1 | ARG 197 | - | VdWContact |
| ARG 34 | CX.4 | GLU 4 | - | Cationic |
| ASN 36 | cxb1.1 | HIS 193 | - | VdWContact |
| ASN 36 | cxb1.1 | ARG 212 | 5.35x36 | HBAcceptor |
| ASN 36 | cxb1.1 | ARG 212 | 5.35x36 | VdWContact |
| CYS 38 | cxb1.5 | ARG 197 | - | Anionic |
| LYS 41 | cxb1.8 | VAL 5 | - | HBDonor |
| LYS 41 | cxb1.8 | VAL 5 | - | VdWContact |
| GLU 42 | cxb1.10 | ARG 197 | - | Anionic |
| GLU 42 | cxb1.10 | ARG 197 | - | HBAcceptor |
| GLU 42 | cxb1.10 | ARG 197 | - | VdWContact |
| ILE 44 | cxb1.14 | PRO 42 | - | Hydrophobic |
| LYS 47 | B1.1 | ASP 35 | - | Cationic |
| LYS 47 | B1.1 | ASP 35 | - | HBDonor |
| LYS 47 | B1.1 | ASP 35 | - | VdWContact |
| LYS 47 | B1.1 | CYS 37 | - | VdWContact |
| LYS 48 | B1.2 | ASP 13 | - | Cationic |
| LYS 48 | B1.2 | ASP 13 | - | HBDonor |
| LYS 48 | B1.2 | ASP 13 | - | VdWContact |
| ASN 49 | B1.3 | ASP 35 | - | HBDonor |
| ASN 49 | B1.3 | ASP 35 | - | VdWContact |
| ILE 52 | B1.6 | PRO 41 | - | VdWContact |
| ILE 52 | B1.6 | PRO 42 | - | Hydrophobic |
| VAL 53 | B1.7 | CYS 38 | - | Hydrophobic |
| VAL 53 | B1.7 | CYS 38 | - | VdWContact |
| VAL 53 | B1.7 | SER 40 | - | VdWContact |
| CYS 54 | b1b2.4 | SER 40 | - | HBAcceptor |
| CYS 54 | b1b2.4 | SER 40 | - | HBDonor |
| CYS 54 | b1b2.4 | SER 40 | - | VdWContact |
| CYS 54 | b1b2.4 | PRO 42 | - | VdWContact |
| GLU 60 | b1b2.12 | TYR 27 | - | HBAcceptor |
| TRP 61 | b1b2.13 | LEU 20 | - | Hydrophobic |
| TRP 61 | b1b2.13 | PHE 23 | - | Hydrophobic |
| TRP 61 | b1b2.13 | PHE 23 | - | VdWContact |
| TRP 61 | b1b2.13 | TYR 27 | - | Hydrophobic |
| ARG 64 | B2.1 | PHE 23 | - | Hydrophobic |
| ARG 64 | B2.1 | PHE 23 | - | VdWContact |
| MET 65 | B2.2 | LEU 11 | - | Hydrophobic |
| MET 65 | B2.2 | LEU 19 | - | Hydrophobic |
| MET 65 | B2.2 | LEU 20 | - | Hydrophobic |
| MET 65 | B2.2 | PHE 23 | - | Hydrophobic |
| MET 65 | B2.2 | PHE 23 | - | VdWContact |
| MET 66 | B2.3 | VAL 5 | - | Hydrophobic |
| VAL 68 | B2.5 | LEU 19 | - | Hydrophobic |
| VAL 68 | B2.5 | LEU 19 | - | VdWContact |
| LEU 69 | B2.6 | LEU 11 | - | Hydrophobic |
| LEU 69 | B2.6 | LEU 11 | - | VdWContact |
| LEU 69 | B2.6 | LEU 19 | - | Hydrophobic |
| LEU 69 | B2.6 | LEU 19 | - | VdWContact |
| ARG 70 | b2b3.2 | MET 1 | - | HBDonor |
| ARG 70 | b2b3.2 | MET 1 | - | VdWContact |
| ARG 70 | b2b3.2 | VAL 2 | - | VdWContact |
| ARG 70 | b2b3.2 | LEU 3 | - | Hydrophobic |
| ARG 70 | b2b3.2 | LEU 3 | - | VdWContact |
| ARG 72 | b2b3.11 | ALA 18 | - | HBDonor |
| ARG 72 | b2b3.11 | ALA 18 | - | VdWContact |
