Predicted complex interactions
CXCL16_HUMAN + CXCR3
SUMMARY
- Chemokine
- CXCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 113
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASN 1 | NTc.Cm56 | GLN 204 | 45.51x51 | VdWContact |
| GLU 2 | NTc.Cm55 | GLN 204 | 45.51x51 | HBAcceptor |
| GLU 2 | NTc.Cm55 | GLN 204 | 45.51x51 | Hydrophobic |
| GLU 2 | NTc.Cm55 | GLN 204 | 45.51x51 | VdWContact |
| GLU 2 | NTc.Cm55 | TYR 205 | 45.52x52 | Hydrophobic |
| GLU 2 | NTc.Cm55 | TYR 205 | 45.52x52 | VdWContact |
| GLU 2 | NTc.Cm55 | ASN 206 | - | VdWContact |
| GLY 3 | NTc.Cm54 | TYR 205 | 45.52x52 | HBAcceptor |
| GLY 3 | NTc.Cm54 | TYR 205 | 45.52x52 | VdWContact |
| SER 4 | NTc.Cm53 | TRP 109 | 2.60x60 | VdWContact |
| SER 4 | NTc.Cm53 | CYS 203 | 45.50x50 | HBDonor |
| SER 4 | NTc.Cm53 | CYS 203 | 45.50x50 | VdWContact |
| VAL 5 | NTc.Cm52 | GLY 128 | 3.29x29 | VdWContact |
| VAL 5 | NTc.Cm52 | PHE 131 | 3.32x32 | Hydrophobic |
| VAL 5 | NTc.Cm52 | PHE 131 | 3.32x32 | VdWContact |
| VAL 5 | NTc.Cm52 | TYR 205 | 45.52x52 | Hydrophobic |
| THR 6 | NTc.Cm51 | TYR 271 | 6.51x51 | HBDonor |
| THR 6 | NTc.Cm51 | TYR 271 | 6.51x51 | Hydrophobic |
| THR 6 | NTc.Cm51 | TYR 271 | 6.51x51 | VdWContact |
| THR 6 | NTc.Cm51 | VAL 275 | 6.55x55 | Hydrophobic |
| THR 6 | NTc.Cm51 | LYS 300 | 7.35x34 | Hydrophobic |
| THR 6 | NTc.Cm51 | LYS 300 | 7.35x34 | VdWContact |
| THR 6 | NTc.Cm51 | SER 304 | 7.39x38 | VdWContact |
| GLY 7 | NTc.Cm50 | LYS 300 | 7.35x34 | VdWContact |
| GLY 7 | NTc.Cm50 | SER 301 | 7.36x35 | VdWContact |
| SER 8 | NTc.Cm49 | ASP 297 | 7.32x31 | HBDonor |
| SER 8 | NTc.Cm49 | ASP 297 | 7.32x31 | VdWContact |
| SER 8 | NTc.Cm49 | LYS 300 | 7.35x34 | HBAcceptor |
| SER 8 | NTc.Cm49 | LYS 300 | 7.35x34 | VdWContact |
| CYS 9 | NTc.Cm48 | ASP 297 | 7.32x31 | Hydrophobic |
| CYS 9 | NTc.Cm48 | ASP 297 | 7.32x31 | VdWContact |
| TYR 10 | NTc.Cm47 | ASP 112 | 2.63x63 | HBDonor |
| TYR 10 | NTc.Cm47 | ASP 112 | 2.63x63 | VdWContact |
| TYR 10 | NTc.Cm47 | HIS 202 | - | Hydrophobic |
| TYR 10 | NTc.Cm47 | HIS 202 | - | PiStacking |
| GLY 12 | NTc.Cm45 | HIS 202 | - | VdWContact |
| ARG 14 | NTc.Cm43 | ASP 46 | 1.25x25 | HBDonor |
| ARG 14 | NTc.Cm43 | ASP 46 | 1.25x25 | VdWContact |
| ARG 14 | NTc.Cm43 | LEU 49 | 1.28x28 | Hydrophobic |
| ARG 14 | NTc.Cm43 | LEU 49 | 1.28x28 | VdWContact |
| ARG 28 | NTc.Cm29 | ARG 197 | - | VdWContact |
| LEU 29 | NTc.Cm28 | ARG 197 | - | HBAcceptor |
| LEU 29 | NTc.Cm28 | ARG 197 | - | VdWContact |
| ARG 30 | NTc.Cm27 | ARG 197 | - | VdWContact |
| LYS 31 | NTc.Cm26 | ARG 197 | - | HBAcceptor |
| LYS 31 | NTc.Cm26 | ARG 197 | - | VdWContact |
| HIS 32 | NTc.Cm25 | ARG 197 | - | Hydrophobic |
| HIS 32 | NTc.Cm25 | ARG 197 | - | VdWContact |
| LEU 33 | NTc.Cm24 | ARG 197 | - | VdWContact |
| ARG 34 | NTc.Cm23 | HIS 193 | - | HBDonor |
| ARG 34 | NTc.Cm23 | HIS 193 | - | VdWContact |
| ARG 38 | NTc.Cm19 | PRO 42 | - | VdWContact |
| ARG 38 | NTc.Cm19 | GLU 293 | 7.28x27 | HBDonor |
| ARG 38 | NTc.Cm19 | GLU 293 | 7.28x27 | VdWContact |
| ARG 38 | NTc.Cm19 | SER 294 | 7.29x28 | VdWContact |
| CYS 39 | NTc.Cm18 | GLN 45 | 1.24x24 | HBAcceptor |
| CYS 39 | NTc.Cm18 | GLN 45 | 1.24x24 | VdWContact |
| CYS 39 | NTc.Cm18 | SER 294 | 7.29x28 | VdWContact |
| CYS 39 | NTc.Cm18 | ASP 297 | 7.32x31 | Hydrophobic |
| CYS 39 | NTc.Cm18 | ASP 297 | 7.32x31 | VdWContact |
| LEU 40 | NTc.Cm17 | GLN 45 | 1.24x24 | VdWContact |
| LEU 40 | NTc.Cm17 | SER 294 | 7.29x28 | VdWContact |
| LEU 40 | NTc.Cm17 | ARG 295 | 7.30x29 | Hydrophobic |
| LEU 40 | NTc.Cm17 | ARG 295 | 7.30x29 | VdWContact |
| LEU 40 | NTc.Cm17 | ASP 297 | 7.32x31 | VdWContact |
| LEU 40 | NTc.Cm17 | VAL 298 | 7.33x32 | Hydrophobic |
| LEU 40 | NTc.Cm17 | VAL 298 | 7.33x32 | VdWContact |
| LEU 40 | NTc.Cm17 | ALA 299 | 7.34x33 | Hydrophobic |
| TYR 41 | NTc.Cm16 | GLN 45 | 1.24x24 | VdWContact |
| TYR 41 | NTc.Cm16 | ASP 46 | 1.25x25 | HBDonor |
| TYR 41 | NTc.Cm16 | ASP 46 | 1.25x25 | Hydrophobic |
| TYR 41 | NTc.Cm16 | ASP 46 | 1.25x25 | VdWContact |
| TYR 41 | NTc.Cm16 | VAL 298 | 7.33x32 | Hydrophobic |
| TYR 42 | NTc.Cm15 | GLN 45 | 1.24x24 | VdWContact |
| TYR 42 | NTc.Cm15 | VAL 298 | 7.33x32 | Hydrophobic |
| TYR 42 | NTc.Cm15 | VAL 298 | 7.33x32 | VdWContact |
| THR 43 | NTc.Cm14 | GLN 45 | 1.24x24 | HBAcceptor |
| ARG 44 | NTc.Cm13 | GLN 204 | 45.51x51 | HBDonor |
| ARG 44 | NTc.Cm13 | GLN 204 | 45.51x51 | VdWContact |
| GLN 46 | NTc.Cm11 | GLN 204 | 45.51x51 | HBAcceptor |
| GLN 46 | NTc.Cm11 | GLN 204 | 45.51x51 | VdWContact |
| LEU 47 | NTc.Cm10 | ASP 195 | - | VdWContact |
| LEU 47 | NTc.Cm10 | ARG 197 | - | VdWContact |
| LEU 48 | NTc.Cm9 | ASP 195 | - | Hydrophobic |
| LEU 48 | NTc.Cm9 | ASP 195 | - | VdWContact |
| LEU 48 | NTc.Cm9 | GLU 196 | - | Hydrophobic |
| SER 49 | NTc.Cm8 | HIS 193 | - | VdWContact |
| SER 49 | NTc.Cm8 | HIS 194 | - | VdWContact |
| SER 49 | NTc.Cm8 | ASP 195 | - | HBAcceptor |
| SER 49 | NTc.Cm8 | ASP 195 | - | HBDonor |
| SER 49 | NTc.Cm8 | ASP 195 | - | VdWContact |
| SER 49 | NTc.Cm8 | ALA 200 | - | HBDonor |
| SER 49 | NTc.Cm8 | ALA 200 | - | VdWContact |
| SER 49 | NTc.Cm8 | HIS 202 | - | VdWContact |
| TRP 50 | NTc.Cm7 | ASP 195 | - | HBDonor |
| TRP 50 | NTc.Cm7 | ASP 195 | - | Hydrophobic |
| TRP 50 | NTc.Cm7 | ASP 195 | - | VdWContact |
| TRP 50 | NTc.Cm7 | ARG 197 | - | Hydrophobic |
| TRP 50 | NTc.Cm7 | ARG 197 | - | VdWContact |
| TRP 50 | NTc.Cm7 | LEU 198 | - | Hydrophobic |
| TRP 50 | NTc.Cm7 | LEU 198 | - | VdWContact |
| TRP 50 | NTc.Cm7 | HIS 202 | - | Hydrophobic |
| TRP 50 | NTc.Cm7 | HIS 202 | - | VdWContact |
| GLY 55 | NTc.Cm2 | GLN 45 | 1.24x24 | VdWContact |
| ASN 56 | NTc.Cm1 | PRO 42 | - | Hydrophobic |
| ASN 56 | NTc.Cm1 | PRO 42 | - | VdWContact |
| ASN 56 | NTc.Cm1 | GLN 45 | 1.24x24 | HBAcceptor |
| ASN 56 | NTc.Cm1 | GLN 45 | 1.24x24 | Hydrophobic |
| ASN 56 | NTc.Cm1 | GLN 45 | 1.24x24 | VdWContact |
| LYS 57 | CX.1 | PRO 44 | - | Hydrophobic |
| LYS 57 | CX.1 | PRO 44 | - | VdWContact |
| GLN 62 | cxb1.5 | PRO 42 | - | Hydrophobic |
| GLN 62 | cxb1.5 | PRO 42 | - | VdWContact |
