Predicted complex interactions
CXCL17_HUMAN + CXCR3
SUMMARY
- Chemokine
- CXCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 142
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 28 | NTc.Cm22 | ARG 197 | - | Anionic |
| GLU 28 | NTc.Cm22 | ARG 197 | - | HBAcceptor |
| GLU 28 | NTc.Cm22 | ARG 197 | - | VdWContact |
| CYS 31 | NTc.Cm19 | ASP 297 | 7.32x31 | VdWContact |
| LYS 32 | NTc.Cm18 | LEU 198 | - | VdWContact |
| LYS 32 | NTc.Cm18 | HIS 202 | - | CationPi |
| LYS 32 | NTc.Cm18 | HIS 202 | - | Hydrophobic |
| LYS 32 | NTc.Cm18 | HIS 202 | - | VdWContact |
| LYS 32 | NTc.Cm18 | GLN 204 | 45.51x51 | VdWContact |
| ASP 33 | NTc.Cm17 | ARG 212 | 5.35x36 | Anionic |
| ASP 33 | NTc.Cm17 | ARG 212 | 5.35x36 | HBAcceptor |
| ASP 33 | NTc.Cm17 | ARG 212 | 5.35x36 | VdWContact |
| ASP 33 | NTc.Cm17 | ARG 216 | 5.39x40 | Anionic |
| ASP 33 | NTc.Cm17 | ARG 216 | 5.39x40 | VdWContact |
| ASP 33 | NTc.Cm17 | LYS 300 | 7.35x34 | Anionic |
| ASP 33 | NTc.Cm17 | LYS 300 | 7.35x34 | HBAcceptor |
| ASP 33 | NTc.Cm17 | LYS 300 | 7.35x34 | Hydrophobic |
| ASP 33 | NTc.Cm17 | LYS 300 | 7.35x34 | VdWContact |
| TRP 34 | NTc.Cm16 | VAL 298 | 7.33x32 | Hydrophobic |
| TRP 34 | NTc.Cm16 | SER 301 | 7.36x35 | VdWContact |
| PHE 35 | NTc.Cm15 | SER 301 | 7.36x35 | VdWContact |
| PHE 35 | NTc.Cm15 | SER 304 | 7.39x38 | VdWContact |
| LEU 36 | NTc.Cm14 | PHE 131 | 3.32x32 | Hydrophobic |
| LEU 36 | NTc.Cm14 | TYR 205 | 45.52x52 | Hydrophobic |
| LEU 36 | NTc.Cm14 | TYR 205 | 45.52x52 | VdWContact |
| LEU 36 | NTc.Cm14 | TYR 271 | 6.51x51 | Hydrophobic |
| LEU 36 | NTc.Cm14 | TYR 271 | 6.51x51 | VdWContact |
| ARG 37 | NTc.Cm13 | TRP 109 | 2.60x60 | VdWContact |
| ARG 37 | NTc.Cm13 | ASP 112 | 2.63x63 | Cationic |
| ARG 37 | NTc.Cm13 | ASP 112 | 2.63x63 | HBDonor |
| ARG 37 | NTc.Cm13 | ASP 112 | 2.63x63 | VdWContact |
| ARG 37 | NTc.Cm13 | CYS 203 | 45.50x50 | VdWContact |
| ARG 37 | NTc.Cm13 | GLN 204 | 45.51x51 | VdWContact |
| ARG 37 | NTc.Cm13 | TYR 205 | 45.52x52 | HBAcceptor |
| ARG 37 | NTc.Cm13 | TYR 205 | 45.52x52 | VdWContact |
| ALA 38 | NTc.Cm12 | TYR 205 | 45.52x52 | Hydrophobic |
| ALA 38 | NTc.Cm12 | TYR 205 | 45.52x52 | VdWContact |
| ALA 38 | NTc.Cm12 | ARG 216 | 5.39x40 | VdWContact |
| PRO 39 | NTc.Cm11 | TYR 205 | 45.52x52 | Hydrophobic |
| PRO 39 | NTc.Cm11 | TYR 205 | 45.52x52 | VdWContact |
| PRO 39 | NTc.Cm11 | PHE 207 | - | Hydrophobic |
| PRO 39 | NTc.Cm11 | PHE 207 | - | VdWContact |
| PRO 39 | NTc.Cm11 | ARG 212 | 5.35x36 | HBAcceptor |
| PRO 39 | NTc.Cm11 | ARG 212 | 5.35x36 | VdWContact |
| ARG 40 | NTc.Cm10 | ASP 195 | - | Cationic |
| ARG 40 | NTc.Cm10 | ASP 195 | - | HBDonor |
| ARG 40 | NTc.Cm10 | ASP 195 | - | VdWContact |
| ARG 40 | NTc.Cm10 | GLN 204 | 45.51x51 | HBDonor |
| ARG 40 | NTc.Cm10 | GLN 204 | 45.51x51 | Hydrophobic |
| ARG 40 | NTc.Cm10 | GLN 204 | 45.51x51 | VdWContact |
| ARG 40 | NTc.Cm10 | TYR 205 | 45.52x52 | HBDonor |
| ARG 40 | NTc.Cm10 | TYR 205 | 45.52x52 | VdWContact |
| ARG 41 | NTc.Cm9 | THR 213 | 5.36x37 | HBDonor |
| ARG 41 | NTc.Cm9 | THR 213 | 5.36x37 | VdWContact |
| ARG 41 | NTc.Cm9 | ASP 282 | 6.62x62 | Cationic |
| ARG 41 | NTc.Cm9 | ASP 282 | 6.62x62 | HBDonor |
| ARG 41 | NTc.Cm9 | ASP 282 | 6.62x62 | VdWContact |
| LYS 42 | NTc.Cm8 | GLN 209 | 5.32x33 | HBDonor |
| LYS 42 | NTc.Cm8 | GLN 209 | 5.32x33 | Hydrophobic |
| LYS 42 | NTc.Cm8 | GLN 209 | 5.32x33 | VdWContact |
| MET 44 | NTc.Cm6 | GLN 209 | 5.32x33 | VdWContact |
| LYS 52 | CX.5 | ARG 288 | - | Hydrophobic |
| LYS 52 | CX.5 | ARG 288 | - | VdWContact |
| PRO 55 | cxb1.5 | SER 294 | 7.29x28 | VdWContact |
| LYS 65 | B1.4 | TYR 27 | - | Hydrophobic |
| LYS 65 | B1.4 | TYR 27 | - | VdWContact |
| THR 66 | B1.5 | TYR 27 | - | VdWContact |
| THR 66 | B1.5 | ASP 28 | - | VdWContact |
| ARG 67 | B1.6 | SER 26 | - | HBDonor |
| ARG 67 | B1.6 | SER 26 | - | VdWContact |
| ARG 67 | B1.6 | ASP 28 | - | Hydrophobic |
| ARG 67 | B1.6 | ASP 28 | - | VdWContact |
| HIS 68 | B1.7 | ASP 28 | - | HBDonor |
| HIS 68 | B1.7 | ASP 28 | - | VdWContact |
| GLN 69 | b1b2.2 | TYR 29 | - | VdWContact |
| GLN 69 | b1b2.2 | GLY 30 | - | VdWContact |
| GLN 69 | b1b2.2 | GLU 31 | - | HBDonor |
| GLN 69 | b1b2.2 | GLU 31 | - | Hydrophobic |
| GLN 69 | b1b2.2 | GLU 31 | - | VdWContact |
| ARG 70 | b1b2.3 | GLU 31 | - | HBDonor |
| ARG 70 | b1b2.3 | GLU 31 | - | VdWContact |
| HIS 71 | b1b2.4 | GLU 31 | - | Hydrophobic |
| HIS 71 | b1b2.4 | GLU 31 | - | VdWContact |
| HIS 71 | b1b2.4 | GLU 33 | - | Hydrophobic |
| ARG 73 | b1b2.7 | ASN 32 | - | HBDonor |
| ARG 73 | b1b2.7 | ASN 32 | - | VdWContact |
| ARG 73 | b1b2.7 | GLU 33 | - | HBDonor |
| ARG 73 | b1b2.7 | GLU 33 | - | VdWContact |
| ARG 73 | b1b2.7 | SER 34 | - | HBDonor |
| ARG 73 | b1b2.7 | SER 34 | - | VdWContact |
| LYS 77 | b1b2.12 | PRO 42 | - | Hydrophobic |
| LYS 77 | b1b2.12 | PRO 42 | - | VdWContact |
| HIS 78 | b1b2.13 | SER 40 | - | VdWContact |
| ALA 81 | b1b2.17 | GLN 45 | 1.24x24 | HBAcceptor |
| ALA 81 | b1b2.17 | GLN 45 | 1.24x24 | VdWContact |
| PHE 85 | b1b2.21 | GLN 45 | 1.24x24 | VdWContact |
| LEU 86 | b1b2.22 | SER 294 | 7.29x28 | VdWContact |
| LEU 86 | b1b2.22 | ASP 297 | 7.32x31 | Hydrophobic |
| LYS 87 | b1b2.23 | ASP 195 | - | Cationic |
| LYS 87 | b1b2.23 | ASP 195 | - | HBDonor |
| LYS 87 | b1b2.23 | ASP 195 | - | VdWContact |
| LYS 87 | b1b2.23 | LEU 198 | - | Hydrophobic |
| LYS 87 | b1b2.23 | LEU 198 | - | VdWContact |
| GLN 88 | b1b2.24 | LEU 49 | 1.28x28 | Hydrophobic |
| GLN 88 | b1b2.24 | LEU 49 | 1.28x28 | VdWContact |
| GLN 90 | B2.1 | HIS 202 | - | VdWContact |
| LEU 91 | B2.2 | LEU 198 | - | Hydrophobic |
| LEU 91 | B2.2 | LEU 198 | - | VdWContact |
| LEU 91 | B2.2 | ALA 200 | - | Hydrophobic |
| LEU 91 | B2.2 | HIS 202 | - | Hydrophobic |
| LEU 91 | B2.2 | HIS 202 | - | VdWContact |
| ARG 92 | B2.3 | SER 48 | 1.27x27 | HBDonor |
| ARG 92 | B2.3 | SER 48 | 1.27x27 | VdWContact |
| ARG 92 | B2.3 | LEU 49 | 1.28x28 | Hydrophobic |
| ARG 92 | B2.3 | ASP 52 | 1.31x31 | Cationic |
| ARG 92 | B2.3 | ASP 52 | 1.31x31 | HBDonor |
| ARG 92 | B2.3 | ASP 52 | 1.31x31 | VdWContact |
| SER 93 | B2.4 | ASP 112 | 2.63x63 | HBDonor |
| SER 93 | B2.4 | ASP 112 | 2.63x63 | VdWContact |
| SER 93 | B2.4 | ALA 113 | 2.64x64 | VdWContact |
| PHE 94 | B2.5 | ASP 52 | 1.31x31 | Hydrophobic |
| PHE 94 | B2.5 | LEU 56 | 1.35x35 | Hydrophobic |
| PHE 94 | B2.5 | LEU 56 | 1.35x35 | VdWContact |
| PHE 94 | B2.5 | TYR 60 | 1.39x39 | VdWContact |
| ALA 95 | B2.6 | TYR 60 | 1.39x39 | Hydrophobic |
| ALA 95 | B2.6 | TYR 60 | 1.39x39 | VdWContact |
| ALA 95 | B2.6 | TRP 109 | 2.60x60 | Hydrophobic |
| ALA 95 | B2.6 | TRP 109 | 2.60x60 | VdWContact |
| ALA 95 | B2.6 | ASP 112 | 2.63x63 | Hydrophobic |
| ALA 95 | B2.6 | ALA 113 | 2.64x64 | Hydrophobic |
| LEU 96 | b2b3.2 | TYR 60 | 1.39x39 | Hydrophobic |
| LEU 96 | b2b3.2 | TYR 60 | 1.39x39 | VdWContact |
| LEU 96 | b2b3.2 | LEU 106 | 2.57x57 | Hydrophobic |
| LEU 96 | b2b3.2 | TYR 308 | 7.43x42 | Hydrophobic |
| LEU 96 | b2b3.2 | TYR 308 | 7.43x42 | VdWContact |
| PRO 97 | b2b3.3 | TRP 109 | 2.60x60 | Hydrophobic |
| PRO 97 | b2b3.3 | TRP 109 | 2.60x60 | VdWContact |
| PRO 97 | b2b3.3 | TYR 308 | 7.43x42 | Hydrophobic |
| PRO 97 | b2b3.3 | TYR 308 | 7.43x42 | VdWContact |
| LEU 98 | b2b3.4 | PHE 131 | 3.32x32 | VdWContact |
| LEU 98 | b2b3.4 | PHE 135 | 3.36x36 | VdWContact |
| LEU 98 | b2b3.4 | TRP 268 | 6.48x48 | VdWContact |
