Predicted complex interactions
CXCL2_HUMAN + CXCR3
SUMMARY
- Chemokine
- CXCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 130
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | PHE 131 | 3.32x32 | VdWContact |
| ALA 1 | NTc.Cm42 | ASP 186 | 4.60x61 | Cationic |
| ALA 1 | NTc.Cm42 | LEU 190 | 4.64x65 | Hydrophobic |
| ALA 1 | NTc.Cm42 | TYR 205 | 45.52x52 | HBDonor |
| ALA 1 | NTc.Cm42 | TYR 205 | 45.52x52 | Hydrophobic |
| ALA 1 | NTc.Cm42 | TYR 205 | 45.52x52 | VdWContact |
| PRO 2 | NTc.Cm41 | TRP 109 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm41 | TRP 109 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm41 | TYR 308 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm41 | TYR 308 | 7.43x42 | VdWContact |
| LEU 3 | NTc.Cm40 | TYR 271 | 6.51x51 | Hydrophobic |
| LEU 3 | NTc.Cm40 | TYR 271 | 6.51x51 | VdWContact |
| LEU 3 | NTc.Cm40 | LYS 300 | 7.35x34 | Hydrophobic |
| LEU 3 | NTc.Cm40 | LYS 300 | 7.35x34 | VdWContact |
| ALA 4 | NTc.Cm39 | HIS 202 | - | Hydrophobic |
| THR 5 | NTc.Cm38 | LEU 49 | 1.28x28 | Hydrophobic |
| THR 5 | NTc.Cm38 | LEU 49 | 1.28x28 | VdWContact |
| GLU 6 | NTc.Cm37 | ARG 216 | 5.39x40 | Anionic |
| GLU 6 | NTc.Cm37 | ARG 216 | 5.39x40 | HBAcceptor |
| GLU 6 | NTc.Cm37 | ARG 216 | 5.39x40 | VdWContact |
| GLU 6 | NTc.Cm37 | LYS 300 | 7.35x34 | Anionic |
| GLU 6 | NTc.Cm37 | LYS 300 | 7.35x34 | HBAcceptor |
| GLU 6 | NTc.Cm37 | LYS 300 | 7.35x34 | VdWContact |
| LEU 7 | NTc.Cm36 | GLN 45 | 1.24x24 | VdWContact |
| LEU 7 | NTc.Cm36 | ARG 197 | - | Hydrophobic |
| LEU 7 | NTc.Cm36 | LEU 198 | - | Hydrophobic |
| LEU 7 | NTc.Cm36 | LEU 198 | - | VdWContact |
| ARG 8 | NTc.Cm35 | GLN 45 | 1.24x24 | HBAcceptor |
| ARG 8 | NTc.Cm35 | GLN 45 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 278 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 278 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 278 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 282 | 6.62x62 | Cationic |
| ARG 8 | NTc.Cm35 | GLU 293 | 7.28x27 | Cationic |
| ARG 8 | NTc.Cm35 | GLU 293 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 297 | 7.32x31 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 297 | 7.32x31 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 297 | 7.32x31 | VdWContact |
| CYS 9 | NTc.Cm34 | ARG 288 | - | HBAcceptor |
| CYS 9 | NTc.Cm34 | ARG 288 | - | VdWContact |
| GLN 10 | NTc.Cm33 | PRO 42 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | PRO 42 | - | VdWContact |
| GLN 10 | NTc.Cm33 | CYS 43 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | CYS 43 | - | VdWContact |
| GLN 10 | NTc.Cm33 | GLN 45 | 1.24x24 | HBDonor |
| GLN 10 | NTc.Cm33 | GLN 45 | 1.24x24 | Hydrophobic |
| GLN 10 | NTc.Cm33 | GLN 45 | 1.24x24 | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 43 | - | VdWContact |
| LEU 12 | NTc.Cm31 | ARG 288 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | ARG 288 | - | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 290 | 7.25x24 | VdWContact |
| GLN 13 | NTc.Cm30 | SER 40 | - | VdWContact |
| LEU 15 | NTc.Cm28 | THR 39 | - | VdWContact |
| LEU 15 | NTc.Cm28 | SER 40 | - | VdWContact |
| GLN 16 | NTc.Cm27 | TYR 29 | - | Hydrophobic |
| GLN 16 | NTc.Cm27 | TYR 29 | - | VdWContact |
| LEU 20 | NTc.Cm23 | VAL 16 | - | Hydrophobic |
| LEU 20 | NTc.Cm23 | VAL 16 | - | VdWContact |
| LEU 20 | NTc.Cm23 | LEU 20 | - | Hydrophobic |
| LEU 20 | NTc.Cm23 | LEU 20 | - | VdWContact |
| ILE 23 | NTc.Cm20 | VAL 16 | - | Hydrophobic |
| GLN 24 | NTc.Cm19 | ASP 13 | - | VdWContact |
| SER 25 | NTc.Cm18 | LEU 11 | - | VdWContact |
| VAL 26 | NTc.Cm17 | VAL 10 | - | VdWContact |
| VAL 26 | NTc.Cm17 | LEU 11 | - | HBAcceptor |
| VAL 26 | NTc.Cm17 | LEU 11 | - | HBDonor |
| VAL 26 | NTc.Cm17 | LEU 11 | - | VdWContact |
| VAL 26 | NTc.Cm17 | VAL 16 | - | Hydrophobic |
| LYS 27 | NTc.Cm16 | HIS 8 | - | CationPi |
| LYS 27 | NTc.Cm16 | HIS 8 | - | HBDonor |
| LYS 27 | NTc.Cm16 | HIS 8 | - | Hydrophobic |
| LYS 27 | NTc.Cm16 | HIS 8 | - | VdWContact |
| LYS 27 | NTc.Cm16 | GLN 9 | - | VdWContact |
| VAL 28 | NTc.Cm15 | VAL 5 | - | Hydrophobic |
| VAL 28 | NTc.Cm15 | ASP 7 | - | VdWContact |
| VAL 28 | NTc.Cm15 | GLN 9 | - | VdWContact |
| LYS 29 | NTc.Cm14 | ARG 197 | - | Hydrophobic |
| SER 30 | NTc.Cm13 | VAL 5 | - | VdWContact |
| SER 30 | NTc.Cm13 | ASP 7 | - | HBDonor |
| SER 30 | NTc.Cm13 | ASP 7 | - | VdWContact |
| SER 30 | NTc.Cm13 | ARG 197 | - | HBAcceptor |
| SER 30 | NTc.Cm13 | ARG 197 | - | VdWContact |
| PRO 33 | NTc.Cm10 | GLN 204 | 45.51x51 | VdWContact |
| PRO 33 | NTc.Cm10 | ARG 212 | 5.35x36 | VdWContact |
| HIS 34 | NTc.Cm9 | ARG 212 | 5.35x36 | HBAcceptor |
| HIS 34 | NTc.Cm9 | ARG 212 | 5.35x36 | PiCation |
| HIS 34 | NTc.Cm9 | ARG 212 | 5.35x36 | VdWContact |
| CYS 35 | NTc.Cm8 | ARG 197 | - | Anionic |
| CYS 35 | NTc.Cm8 | ARG 197 | - | VdWContact |
| GLN 37 | NTc.Cm6 | ARG 197 | - | VdWContact |
| GLU 39 | NTc.Cm4 | ARG 197 | - | Anionic |
| GLU 39 | NTc.Cm4 | ARG 197 | - | HBAcceptor |
| GLU 39 | NTc.Cm4 | ARG 197 | - | VdWContact |
| ILE 41 | NTc.Cm2 | PRO 42 | - | Hydrophobic |
| LYS 45 | CX.5 | ASP 13 | - | Cationic |
| LYS 45 | CX.5 | ASP 13 | - | HBDonor |
| LYS 45 | CX.5 | ASP 13 | - | VdWContact |
| GLN 48 | cxb1.5 | CYS 38 | - | VdWContact |
| LYS 49 | cxb1.6 | PRO 41 | - | VdWContact |
| LYS 49 | cxb1.6 | PRO 42 | - | Hydrophobic |
| CYS 51 | cxb1.10 | SER 40 | - | HBDonor |
| CYS 51 | cxb1.10 | SER 40 | - | VdWContact |
| PRO 57 | B1.2 | TYR 27 | - | Hydrophobic |
| MET 58 | B1.3 | PHE 23 | - | VdWContact |
| MET 58 | B1.3 | TYR 29 | - | Hydrophobic |
| LYS 61 | B1.6 | PHE 23 | - | Hydrophobic |
| LYS 61 | B1.6 | PHE 23 | - | VdWContact |
| ILE 62 | B1.7 | LEU 11 | - | Hydrophobic |
| ILE 62 | B1.7 | LEU 11 | - | VdWContact |
| ILE 62 | B1.7 | PHE 23 | - | Hydrophobic |
| ILE 63 | b1b2.4 | LEU 3 | - | Hydrophobic |
| ILE 63 | b1b2.4 | VAL 5 | - | Hydrophobic |
| ILE 63 | b1b2.4 | VAL 5 | - | VdWContact |
| GLU 64 | b1b2.6 | LEU 3 | - | Hydrophobic |
| LYS 65 | b1b2.7 | ALA 18 | - | VdWContact |
| LYS 65 | b1b2.7 | LEU 19 | - | HBDonor |
| LYS 65 | b1b2.7 | LEU 19 | - | Hydrophobic |
| LYS 65 | b1b2.7 | LEU 19 | - | VdWContact |
| MET 66 | b1b2.8 | GLN 9 | - | Hydrophobic |
| MET 66 | b1b2.8 | GLN 9 | - | VdWContact |
| MET 66 | b1b2.8 | LEU 11 | - | Hydrophobic |
| MET 66 | b1b2.8 | LEU 11 | - | VdWContact |
| LEU 67 | b1b2.9 | LEU 3 | - | Hydrophobic |
| LEU 67 | b1b2.9 | LEU 3 | - | VdWContact |
| LEU 67 | b1b2.9 | GLU 4 | - | VdWContact |
| LEU 67 | b1b2.9 | VAL 5 | - | Hydrophobic |
| LEU 67 | b1b2.9 | VAL 5 | - | VdWContact |
| ASN 69 | b1b2.12 | GLU 15 | - | HBDonor |
| ASN 69 | b1b2.12 | GLU 15 | - | VdWContact |
| GLY 70 | b1b2.13 | GLN 9 | - | VdWContact |
