Predicted complex interactions
CXCL4_HUMAN + CXCR3
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 108
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 1 | NTc.Cm40 | TRP 109 | 2.60x60 | Hydrophobic |
| GLU 1 | NTc.Cm40 | TRP 109 | 2.60x60 | VdWContact |
| GLU 1 | NTc.Cm40 | GLY 128 | 3.29x29 | VdWContact |
| GLU 1 | NTc.Cm40 | CYS 203 | 45.50x50 | HBAcceptor |
| GLU 1 | NTc.Cm40 | CYS 203 | 45.50x50 | Hydrophobic |
| GLU 1 | NTc.Cm40 | CYS 203 | 45.50x50 | VdWContact |
| ALA 2 | NTc.Cm39 | TYR 308 | 7.43x42 | Hydrophobic |
| ALA 2 | NTc.Cm39 | TYR 308 | 7.43x42 | VdWContact |
| GLU 3 | NTc.Cm38 | TYR 205 | 45.52x52 | Hydrophobic |
| GLU 3 | NTc.Cm38 | TYR 205 | 45.52x52 | VdWContact |
| GLU 3 | NTc.Cm38 | ARG 212 | 5.35x36 | Anionic |
| GLU 3 | NTc.Cm38 | ARG 216 | 5.39x40 | Anionic |
| GLU 3 | NTc.Cm38 | ARG 216 | 5.39x40 | HBAcceptor |
| GLU 3 | NTc.Cm38 | ARG 216 | 5.39x40 | VdWContact |
| GLU 4 | NTc.Cm37 | LEU 56 | 1.35x35 | Hydrophobic |
| GLU 4 | NTc.Cm37 | LEU 56 | 1.35x35 | VdWContact |
| ASP 5 | NTc.Cm36 | ARG 212 | 5.35x36 | Anionic |
| ASP 5 | NTc.Cm36 | ARG 212 | 5.35x36 | HBAcceptor |
| ASP 5 | NTc.Cm36 | ARG 212 | 5.35x36 | VdWContact |
| ASP 7 | NTc.Cm34 | ARG 212 | 5.35x36 | Anionic |
| ASP 7 | NTc.Cm34 | ARG 212 | 5.35x36 | VdWContact |
| ASP 7 | NTc.Cm34 | LYS 300 | 7.35x34 | Anionic |
| ASP 7 | NTc.Cm34 | LYS 300 | 7.35x34 | VdWContact |
| LEU 8 | NTc.Cm33 | GLN 45 | 1.24x24 | VdWContact |
| LEU 8 | NTc.Cm33 | ASP 195 | - | VdWContact |
| LEU 8 | NTc.Cm33 | ARG 197 | - | HBAcceptor |
| LEU 8 | NTc.Cm33 | ARG 197 | - | VdWContact |
| LEU 8 | NTc.Cm33 | LEU 198 | - | Hydrophobic |
| LEU 8 | NTc.Cm33 | LEU 198 | - | VdWContact |
| GLN 9 | NTc.Cm32 | ARG 197 | - | VdWContact |
| GLN 9 | NTc.Cm32 | ARG 288 | - | VdWContact |
| GLN 9 | NTc.Cm32 | GLU 293 | 7.28x27 | VdWContact |
| CYS 10 | NTc.Cm31 | ARG 288 | - | Anionic |
| CYS 10 | NTc.Cm31 | ARG 288 | - | HBAcceptor |
| CYS 10 | NTc.Cm31 | ARG 288 | - | VdWContact |
| LEU 11 | NTc.Cm30 | PRO 42 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | PRO 42 | - | VdWContact |
| LEU 11 | NTc.Cm30 | CYS 43 | - | HBAcceptor |
| LEU 11 | NTc.Cm30 | CYS 43 | - | VdWContact |
| LEU 11 | NTc.Cm30 | GLN 45 | 1.24x24 | Hydrophobic |
| LEU 11 | NTc.Cm30 | ARG 197 | - | VdWContact |
| VAL 13 | NTc.Cm28 | CYS 43 | - | VdWContact |
| VAL 13 | NTc.Cm28 | ARG 288 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | ARG 288 | - | VdWContact |
| LYS 14 | NTc.Cm27 | SER 40 | - | VdWContact |
| THR 16 | NTc.Cm25 | SER 40 | - | HBAcceptor |
| THR 16 | NTc.Cm25 | SER 40 | - | VdWContact |
| GLN 18 | NTc.Cm23 | TYR 29 | - | Hydrophobic |
| GLN 18 | NTc.Cm23 | GLU 33 | - | HBDonor |
| GLN 18 | NTc.Cm23 | GLU 33 | - | VdWContact |
| ARG 20 | NTc.Cm21 | GLU 31 | - | HBDonor |
| ARG 20 | NTc.Cm21 | GLU 31 | - | VdWContact |
| ARG 20 | NTc.Cm21 | ASP 35 | - | Cationic |
| PRO 21 | NTc.Cm20 | LEU 20 | - | Hydrophobic |
| PRO 21 | NTc.Cm20 | LEU 20 | - | VdWContact |
| ILE 24 | NTc.Cm17 | VAL 16 | - | Hydrophobic |
| THR 25 | NTc.Cm16 | ASP 13 | - | VdWContact |
| SER 26 | NTc.Cm15 | LEU 11 | - | VdWContact |
| LEU 27 | NTc.Cm14 | LEU 11 | - | HBAcceptor |
| LEU 27 | NTc.Cm14 | LEU 11 | - | HBDonor |
| LEU 27 | NTc.Cm14 | LEU 11 | - | Hydrophobic |
| LEU 27 | NTc.Cm14 | LEU 11 | - | VdWContact |
| LEU 27 | NTc.Cm14 | VAL 16 | - | Hydrophobic |
| GLU 28 | NTc.Cm13 | HIS 8 | - | HBAcceptor |
| GLU 28 | NTc.Cm13 | HIS 8 | - | Hydrophobic |
| GLU 28 | NTc.Cm13 | HIS 8 | - | VdWContact |
| GLU 28 | NTc.Cm13 | GLN 9 | - | VdWContact |
| GLU 28 | NTc.Cm13 | VAL 10 | - | Hydrophobic |
| VAL 29 | NTc.Cm12 | HIS 8 | - | VdWContact |
| VAL 29 | NTc.Cm12 | GLN 9 | - | HBAcceptor |
| VAL 29 | NTc.Cm12 | GLN 9 | - | HBDonor |
| VAL 29 | NTc.Cm12 | GLN 9 | - | Hydrophobic |
| VAL 29 | NTc.Cm12 | GLN 9 | - | VdWContact |
| ILE 30 | NTc.Cm11 | HIS 8 | - | Hydrophobic |
| ILE 30 | NTc.Cm11 | HIS 8 | - | VdWContact |
| ILE 30 | NTc.Cm11 | ARG 197 | - | Hydrophobic |
| ILE 30 | NTc.Cm11 | ARG 197 | - | VdWContact |
| LYS 31 | NTc.Cm10 | VAL 5 | - | HBDonor |
| LYS 31 | NTc.Cm10 | VAL 5 | - | VdWContact |
| LYS 31 | NTc.Cm10 | ASP 7 | - | Cationic |
| LYS 31 | NTc.Cm10 | ASP 7 | - | HBDonor |
| LYS 31 | NTc.Cm10 | ASP 7 | - | Hydrophobic |
| LYS 31 | NTc.Cm10 | ASP 7 | - | VdWContact |
| HIS 35 | NTc.Cm6 | GLN 204 | 45.51x51 | Hydrophobic |
| HIS 35 | NTc.Cm6 | GLN 204 | 45.51x51 | VdWContact |
| ILE 42 | CX.4 | PRO 42 | - | Hydrophobic |
| LYS 50 | cxb1.11 | PRO 41 | - | VdWContact |
| LYS 50 | cxb1.11 | PRO 42 | - | Hydrophobic |
| LYS 50 | cxb1.11 | PRO 42 | - | VdWContact |
| ILE 51 | cxb1.14 | THR 39 | - | Hydrophobic |
| CYS 52 | cxb1.15 | SER 40 | - | HBDonor |
| CYS 52 | cxb1.15 | SER 40 | - | VdWContact |
| PRO 58 | B1.5 | TYR 27 | - | Hydrophobic |
| PRO 58 | B1.5 | TYR 27 | - | VdWContact |
| LEU 59 | B1.6 | LEU 20 | - | Hydrophobic |
| LEU 59 | B1.6 | PHE 23 | - | Hydrophobic |
| LEU 59 | B1.6 | TYR 27 | - | Hydrophobic |
| LEU 59 | B1.6 | TYR 27 | - | VdWContact |
| LYS 62 | b1b2.6 | PHE 23 | - | Hydrophobic |
| LYS 62 | b1b2.6 | PHE 23 | - | VdWContact |
| ILE 63 | b1b2.7 | LEU 19 | - | Hydrophobic |
| ILE 63 | b1b2.7 | LEU 20 | - | Hydrophobic |
| ILE 63 | b1b2.7 | LEU 20 | - | VdWContact |
| ILE 63 | b1b2.7 | PHE 23 | - | Hydrophobic |
| LYS 66 | b1b2.10 | LEU 19 | - | Hydrophobic |
| LEU 67 | b1b2.12 | LEU 11 | - | Hydrophobic |
| LEU 67 | b1b2.12 | LEU 11 | - | VdWContact |
| SER 70 | b1b2.16 | VAL 5 | - | VdWContact |
