Predicted complex interactions
CXCL5_HUMAN + CXCR3
SUMMARY
- Chemokine
- CXCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 144
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm48 | LEU 56 | 1.35x35 | Hydrophobic |
| ALA 1 | NTc.Cm48 | LEU 56 | 1.35x35 | VdWContact |
| ALA 1 | NTc.Cm48 | TRP 109 | 2.60x60 | HBDonor |
| ALA 1 | NTc.Cm48 | TRP 109 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm48 | ASP 112 | 2.63x63 | Cationic |
| ALA 1 | NTc.Cm48 | ASP 112 | 2.63x63 | HBDonor |
| ALA 1 | NTc.Cm48 | ASP 112 | 2.63x63 | VdWContact |
| ALA 1 | NTc.Cm48 | ALA 113 | 2.64x64 | VdWContact |
| GLY 2 | NTc.Cm47 | TYR 60 | 1.39x39 | HBDonor |
| GLY 2 | NTc.Cm47 | TYR 60 | 1.39x39 | VdWContact |
| GLY 2 | NTc.Cm47 | TRP 109 | 2.60x60 | VdWContact |
| GLY 2 | NTc.Cm47 | TYR 308 | 7.43x42 | VdWContact |
| PRO 3 | NTc.Cm46 | TRP 109 | 2.60x60 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TRP 109 | 2.60x60 | VdWContact |
| PRO 3 | NTc.Cm46 | GLY 128 | 3.29x29 | VdWContact |
| PRO 3 | NTc.Cm46 | PHE 131 | 3.32x32 | Hydrophobic |
| PRO 3 | NTc.Cm46 | PHE 131 | 3.32x32 | VdWContact |
| PRO 3 | NTc.Cm46 | TYR 308 | 7.43x42 | VdWContact |
| ALA 4 | NTc.Cm45 | PHE 131 | 3.32x32 | Hydrophobic |
| ALA 4 | NTc.Cm45 | TYR 271 | 6.51x51 | Hydrophobic |
| ALA 4 | NTc.Cm45 | TYR 271 | 6.51x51 | VdWContact |
| ALA 5 | NTc.Cm44 | LEU 56 | 1.35x35 | Hydrophobic |
| ALA 6 | NTc.Cm43 | TRP 109 | 2.60x60 | Hydrophobic |
| ALA 6 | NTc.Cm43 | CYS 203 | 45.50x50 | VdWContact |
| VAL 7 | NTc.Cm42 | TYR 205 | 45.52x52 | Hydrophobic |
| VAL 7 | NTc.Cm42 | TYR 205 | 45.52x52 | VdWContact |
| LEU 8 | NTc.Cm41 | ARG 216 | 5.39x40 | VdWContact |
| LEU 8 | NTc.Cm41 | TYR 271 | 6.51x51 | Hydrophobic |
| LEU 8 | NTc.Cm41 | LYS 300 | 7.35x34 | Hydrophobic |
| LEU 8 | NTc.Cm41 | LYS 300 | 7.35x34 | VdWContact |
| ARG 9 | NTc.Cm40 | LEU 49 | 1.28x28 | Hydrophobic |
| ARG 9 | NTc.Cm40 | LEU 49 | 1.28x28 | VdWContact |
| ARG 9 | NTc.Cm40 | ALA 113 | 2.64x64 | HBDonor |
| ARG 9 | NTc.Cm40 | HIS 202 | - | VdWContact |
| GLU 10 | NTc.Cm39 | ARG 212 | 5.35x36 | Anionic |
| GLU 10 | NTc.Cm39 | ARG 216 | 5.39x40 | Anionic |
| GLU 10 | NTc.Cm39 | ARG 216 | 5.39x40 | HBAcceptor |
| GLU 10 | NTc.Cm39 | ARG 216 | 5.39x40 | VdWContact |
| GLU 10 | NTc.Cm39 | ASP 278 | 6.58x58 | VdWContact |
| GLU 10 | NTc.Cm39 | LYS 300 | 7.35x34 | Anionic |
| GLU 10 | NTc.Cm39 | LYS 300 | 7.35x34 | VdWContact |
| LEU 11 | NTc.Cm38 | GLN 45 | 1.24x24 | VdWContact |
| LEU 11 | NTc.Cm38 | ASP 195 | - | Hydrophobic |
| LEU 11 | NTc.Cm38 | ASP 195 | - | VdWContact |
| LEU 11 | NTc.Cm38 | ARG 197 | - | Hydrophobic |
| LEU 11 | NTc.Cm38 | LEU 198 | - | Hydrophobic |
| LEU 11 | NTc.Cm38 | GLN 204 | 45.51x51 | VdWContact |
| ARG 12 | NTc.Cm37 | ASP 278 | 6.58x58 | Cationic |
| ARG 12 | NTc.Cm37 | ASP 278 | 6.58x58 | HBDonor |
| ARG 12 | NTc.Cm37 | ASP 278 | 6.58x58 | VdWContact |
| ARG 12 | NTc.Cm37 | MET 281 | 6.61x61 | VdWContact |
| ARG 12 | NTc.Cm37 | GLU 293 | 7.28x27 | Cationic |
| ARG 12 | NTc.Cm37 | GLU 293 | 7.28x27 | VdWContact |
| ARG 12 | NTc.Cm37 | ASP 297 | 7.32x31 | Cationic |
| ARG 12 | NTc.Cm37 | ASP 297 | 7.32x31 | HBDonor |
| ARG 12 | NTc.Cm37 | ASP 297 | 7.32x31 | VdWContact |
| CYS 13 | NTc.Cm36 | ARG 288 | - | HBAcceptor |
| CYS 13 | NTc.Cm36 | ARG 288 | - | VdWContact |
| VAL 14 | NTc.Cm35 | PRO 42 | - | Hydrophobic |
| VAL 14 | NTc.Cm35 | PRO 42 | - | VdWContact |
| VAL 14 | NTc.Cm35 | CYS 43 | - | HBAcceptor |
| VAL 14 | NTc.Cm35 | CYS 43 | - | VdWContact |
| VAL 14 | NTc.Cm35 | GLN 45 | 1.24x24 | Hydrophobic |
| VAL 14 | NTc.Cm35 | GLN 45 | 1.24x24 | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 43 | - | VdWContact |
| LEU 16 | NTc.Cm33 | ARG 288 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | ARG 288 | - | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 290 | 7.25x24 | Hydrophobic |
| LEU 16 | NTc.Cm33 | CYS 290 | 7.25x24 | VdWContact |
| GLN 17 | NTc.Cm32 | SER 40 | - | VdWContact |
| THR 19 | NTc.Cm30 | THR 39 | - | Hydrophobic |
| THR 19 | NTc.Cm30 | THR 39 | - | VdWContact |
| THR 19 | NTc.Cm30 | SER 40 | - | HBAcceptor |
| THR 19 | NTc.Cm30 | SER 40 | - | VdWContact |
| GLY 21 | NTc.Cm28 | TYR 29 | - | VdWContact |
| HIS 23 | NTc.Cm26 | TYR 29 | - | Hydrophobic |
| PRO 24 | NTc.Cm25 | LEU 20 | - | Hydrophobic |
| PRO 24 | NTc.Cm25 | LEU 20 | - | VdWContact |
| PRO 24 | NTc.Cm25 | TYR 29 | - | Hydrophobic |
| ILE 27 | NTc.Cm22 | VAL 16 | - | Hydrophobic |
| SER 28 | NTc.Cm21 | ASP 13 | - | VdWContact |
| ASN 29 | NTc.Cm20 | LEU 11 | - | VdWContact |
| LEU 30 | NTc.Cm19 | VAL 10 | - | VdWContact |
| LEU 30 | NTc.Cm19 | LEU 11 | - | HBAcceptor |
| LEU 30 | NTc.Cm19 | LEU 11 | - | HBDonor |
| LEU 30 | NTc.Cm19 | LEU 11 | - | Hydrophobic |
| LEU 30 | NTc.Cm19 | LEU 11 | - | VdWContact |
| LEU 30 | NTc.Cm19 | VAL 16 | - | Hydrophobic |
| GLN 31 | NTc.Cm18 | HIS 8 | - | Hydrophobic |
| GLN 31 | NTc.Cm18 | GLN 9 | - | VdWContact |
| GLN 31 | NTc.Cm18 | VAL 10 | - | Hydrophobic |
| VAL 32 | NTc.Cm17 | VAL 5 | - | Hydrophobic |
| VAL 32 | NTc.Cm17 | HIS 8 | - | VdWContact |
| VAL 32 | NTc.Cm17 | GLN 9 | - | HBAcceptor |
| VAL 32 | NTc.Cm17 | GLN 9 | - | HBDonor |
| VAL 32 | NTc.Cm17 | GLN 9 | - | VdWContact |
| PHE 33 | NTc.Cm16 | HIS 8 | - | Hydrophobic |
| PHE 33 | NTc.Cm16 | HIS 8 | - | VdWContact |
| PHE 33 | NTc.Cm16 | ARG 197 | - | Hydrophobic |
| PHE 33 | NTc.Cm16 | ARG 197 | - | PiCation |
| PHE 33 | NTc.Cm16 | ARG 197 | - | VdWContact |
| ALA 34 | NTc.Cm15 | VAL 5 | - | Hydrophobic |
| ALA 34 | NTc.Cm15 | VAL 5 | - | VdWContact |
| ALA 34 | NTc.Cm15 | SER 6 | - | VdWContact |
| ALA 34 | NTc.Cm15 | ASP 7 | - | HBDonor |
| ALA 34 | NTc.Cm15 | ASP 7 | - | VdWContact |
| GLN 38 | NTc.Cm11 | GLN 204 | 45.51x51 | HBDonor |
| GLN 38 | NTc.Cm11 | GLN 204 | 45.51x51 | VdWContact |
| GLN 38 | NTc.Cm11 | ARG 212 | 5.35x36 | HBAcceptor |
| GLN 38 | NTc.Cm11 | ARG 212 | 5.35x36 | VdWContact |
| GLU 43 | NTc.Cm6 | ARG 197 | - | Anionic |
| GLU 43 | NTc.Cm6 | ARG 197 | - | HBAcceptor |
| GLU 43 | NTc.Cm6 | ARG 197 | - | VdWContact |
| VAL 45 | NTc.Cm4 | PRO 42 | - | Hydrophobic |
| LYS 49 | CX.1 | ASP 13 | - | Cationic |
| LYS 49 | CX.1 | ASP 13 | - | VdWContact |
| GLU 53 | cxb1.2 | PRO 41 | - | VdWContact |
| GLU 53 | cxb1.2 | PRO 42 | - | Hydrophobic |
| ILE 54 | cxb1.5 | THR 39 | - | Hydrophobic |
| ILE 54 | cxb1.5 | PRO 41 | - | VdWContact |
| CYS 55 | cxb1.6 | SER 40 | - | HBDonor |
| CYS 55 | cxb1.6 | SER 40 | - | VdWContact |
| PRO 61 | cxb1.16 | TYR 27 | - | Hydrophobic |
| PRO 61 | cxb1.16 | TYR 27 | - | VdWContact |
| PHE 62 | B1.1 | LEU 20 | - | Hydrophobic |
| PHE 62 | B1.1 | PHE 23 | - | Hydrophobic |
| PHE 62 | B1.1 | PHE 23 | - | VdWContact |
| LYS 65 | B1.4 | PHE 23 | - | Hydrophobic |
| LYS 65 | B1.4 | PHE 23 | - | VdWContact |
| VAL 66 | B1.5 | LEU 11 | - | Hydrophobic |
| VAL 66 | B1.5 | LEU 11 | - | VdWContact |
| VAL 66 | B1.5 | LEU 19 | - | Hydrophobic |
| VAL 66 | B1.5 | LEU 19 | - | VdWContact |
| ILE 67 | B1.6 | LEU 3 | - | Hydrophobic |
| ILE 67 | B1.6 | VAL 5 | - | Hydrophobic |
| LYS 69 | b1b2.4 | LEU 19 | - | Hydrophobic |
| ILE 70 | b1b2.6 | GLN 9 | - | Hydrophobic |
| ILE 70 | b1b2.6 | GLN 9 | - | VdWContact |
| ILE 70 | b1b2.6 | LEU 11 | - | Hydrophobic |
| ILE 70 | b1b2.6 | LEU 11 | - | VdWContact |
| LEU 71 | b1b2.7 | LEU 3 | - | Hydrophobic |
| LEU 71 | b1b2.7 | LEU 3 | - | VdWContact |
| LEU 71 | b1b2.7 | VAL 5 | - | Hydrophobic |
| LEU 71 | b1b2.7 | VAL 5 | - | VdWContact |
