Predicted complex interactions
CXCL6_HUMAN + ACKR2
SUMMARY
- Chemokine
- CXCL6_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 116
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm48 | TRP 102 | 2.60x60 | VdWContact |
| GLY 1 | NTc.Cm48 | SER 121 | 3.29x29 | HBDonor |
| GLY 1 | NTc.Cm48 | SER 121 | 3.29x29 | VdWContact |
| PRO 2 | NTc.Cm47 | TYR 53 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TYR 53 | 1.39x39 | VdWContact |
| PRO 2 | NTc.Cm47 | TRP 102 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TRP 102 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm47 | GLU 298 | 7.39x38 | Hydrophobic |
| PRO 2 | NTc.Cm47 | GLU 298 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm47 | PHE 302 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm47 | PHE 302 | 7.43x42 | VdWContact |
| VAL 3 | NTc.Cm46 | LEU 294 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm46 | LEU 294 | 7.35x34 | VdWContact |
| VAL 3 | NTc.Cm46 | GLN 295 | 7.36x35 | Hydrophobic |
| VAL 3 | NTc.Cm46 | GLN 295 | 7.36x35 | VdWContact |
| VAL 3 | NTc.Cm46 | GLU 298 | 7.39x38 | HBDonor |
| VAL 3 | NTc.Cm46 | GLU 298 | 7.39x38 | Hydrophobic |
| VAL 3 | NTc.Cm46 | GLU 298 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm45 | VAL 106 | 2.64x64 | VdWContact |
| VAL 6 | NTc.Cm43 | HIS 273 | 6.58x58 | Hydrophobic |
| VAL 6 | NTc.Cm43 | ASP 291 | 7.32x31 | Hydrophobic |
| VAL 6 | NTc.Cm43 | LEU 294 | 7.35x34 | Hydrophobic |
| VAL 6 | NTc.Cm43 | LEU 294 | 7.35x34 | VdWContact |
| LEU 7 | NTc.Cm42 | VAL 41 | 1.27x27 | Hydrophobic |
| LEU 7 | NTc.Cm42 | VAL 42 | 1.28x28 | Hydrophobic |
| LEU 7 | NTc.Cm42 | VAL 42 | 1.28x28 | VdWContact |
| GLU 9 | NTc.Cm40 | HIS 196 | 45.51x51 | Hydrophobic |
| GLU 9 | NTc.Cm40 | HIS 196 | 45.51x51 | VdWContact |
| GLU 9 | NTc.Cm40 | ALA 197 | 45.52x52 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ALA 197 | 45.52x52 | VdWContact |
| GLU 9 | NTc.Cm40 | LYS 207 | 5.35x36 | HBAcceptor |
| GLU 9 | NTc.Cm40 | LYS 207 | 5.35x36 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 211 | 5.39x40 | Anionic |
| LEU 10 | NTc.Cm39 | LYS 38 | 1.24x24 | Hydrophobic |
| LEU 10 | NTc.Cm39 | LYS 38 | 1.24x24 | VdWContact |
| LEU 10 | NTc.Cm39 | HIS 273 | 6.58x58 | Hydrophobic |
| LEU 10 | NTc.Cm39 | ASP 291 | 7.32x31 | VdWContact |
| ARG 11 | NTc.Cm38 | THR 204 | 5.32x33 | VdWContact |
| ARG 11 | NTc.Cm38 | LYS 207 | 5.35x36 | Hydrophobic |
| ARG 11 | NTc.Cm38 | LYS 207 | 5.35x36 | VdWContact |
| ARG 11 | NTc.Cm38 | LEU 208 | 5.36x37 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 277 | 6.62x62 | Cationic |
| ARG 11 | NTc.Cm38 | ASP 277 | 6.62x62 | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 277 | 6.62x62 | Hydrophobic |
| ARG 11 | NTc.Cm38 | ASP 277 | 6.62x62 | VdWContact |
| THR 13 | NTc.Cm36 | GLN 279 | 6.64x64 | HBAcceptor |
| THR 13 | NTc.Cm36 | GLN 279 | 6.64x64 | VdWContact |
| LEU 15 | NTc.Cm34 | THR 204 | 5.32x33 | Hydrophobic |
| LEU 15 | NTc.Cm34 | THR 204 | 5.32x33 | VdWContact |
| LEU 15 | NTc.Cm34 | ASP 277 | 6.62x62 | VdWContact |
| ASN 22 | NTc.Cm27 | TYR 24 | - | VdWContact |
| PRO 23 | NTc.Cm26 | TYR 24 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | TYR 24 | - | VdWContact |
| PRO 23 | NTc.Cm26 | TYR 27 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | TYR 27 | - | VdWContact |
| PRO 23 | NTc.Cm26 | LEU 28 | - | Hydrophobic |
| LYS 24 | NTc.Cm25 | TYR 24 | - | Hydrophobic |
| LYS 24 | NTc.Cm25 | TYR 27 | - | Hydrophobic |
| LYS 24 | NTc.Cm25 | TYR 27 | - | VdWContact |
| ILE 26 | NTc.Cm23 | TYR 27 | - | VdWContact |
| ILE 26 | NTc.Cm23 | LEU 28 | - | Hydrophobic |
| ILE 26 | NTc.Cm23 | VAL 31 | - | Hydrophobic |
| GLY 27 | NTc.Cm22 | VAL 31 | - | VdWContact |
| LYS 28 | NTc.Cm21 | ALA 32 | - | VdWContact |
| LYS 28 | NTc.Cm21 | MET 34 | - | VdWContact |
| LEU 29 | NTc.Cm20 | LEU 28 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | VAL 31 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | ALA 32 | - | HBDonor |
| LEU 29 | NTc.Cm20 | ALA 32 | - | VdWContact |
| LEU 29 | NTc.Cm20 | PHE 33 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | PHE 33 | - | VdWContact |
| LEU 29 | NTc.Cm20 | MET 34 | - | HBAcceptor |
| LEU 29 | NTc.Cm20 | MET 34 | - | VdWContact |
| GLN 30 | NTc.Cm19 | MET 34 | - | VdWContact |
| GLN 30 | NTc.Cm19 | CYS 284 | 7.25x24 | HBAcceptor |
| GLN 30 | NTc.Cm19 | CYS 284 | 7.25x24 | VdWContact |
| VAL 31 | NTc.Cm18 | MET 34 | - | HBDonor |
| VAL 31 | NTc.Cm18 | MET 34 | - | VdWContact |
| VAL 31 | NTc.Cm18 | CYS 36 | - | HBAcceptor |
| VAL 31 | NTc.Cm18 | CYS 36 | - | VdWContact |
| PHE 32 | NTc.Cm17 | CYS 36 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | CYS 36 | - | VdWContact |
| PRO 33 | NTc.Cm16 | LEU 35 | - | Hydrophobic |
| PRO 33 | NTc.Cm16 | LEU 35 | - | VdWContact |
| PRO 36 | NTc.Cm13 | HIS 196 | 45.51x51 | Hydrophobic |
| GLN 37 | NTc.Cm12 | LYS 38 | 1.24x24 | VdWContact |
| LYS 48 | NTc.Cm1 | TYR 27 | - | HBDonor |
| LYS 48 | NTc.Cm1 | TYR 27 | - | VdWContact |
| GLN 52 | cxb1.1 | GLY 282 | - | HBDonor |
| GLN 52 | cxb1.1 | GLY 282 | - | VdWContact |
| GLN 52 | cxb1.1 | ASN 283 | 7.24x23 | HBDonor |
| GLN 52 | cxb1.1 | ASN 283 | 7.24x23 | VdWContact |
| CYS 54 | cxb1.5 | GLN 279 | 6.64x64 | VdWContact |
| PRO 60 | cxb1.15 | TYR 25 | - | HBAcceptor |
| PRO 60 | cxb1.15 | TYR 25 | - | VdWContact |
| PHE 61 | cxb1.16 | TYR 24 | - | Hydrophobic |
| PHE 61 | cxb1.16 | TYR 25 | - | VdWContact |
| PHE 61 | cxb1.16 | LEU 28 | - | Hydrophobic |
| PHE 61 | cxb1.16 | LEU 28 | - | VdWContact |
| LYS 64 | B1.3 | TYR 25 | - | HBDonor |
| LYS 64 | B1.3 | TYR 25 | - | Hydrophobic |
| LYS 64 | B1.3 | TYR 25 | - | VdWContact |
| VAL 65 | B1.4 | TYR 25 | - | Hydrophobic |
| VAL 65 | B1.4 | LEU 28 | - | Hydrophobic |
| VAL 65 | B1.4 | PHE 33 | - | Hydrophobic |
| VAL 65 | B1.4 | PHE 33 | - | VdWContact |
| LYS 68 | B1.7 | ASP 29 | - | Cationic |
| LYS 68 | B1.7 | ASP 29 | - | HBDonor |
| LYS 68 | B1.7 | ASP 29 | - | VdWContact |
| ILE 69 | b1b2.4 | PHE 33 | - | Hydrophobic |
| ILE 69 | b1b2.4 | PHE 33 | - | VdWContact |
| ILE 69 | b1b2.4 | LEU 35 | - | Hydrophobic |
| ILE 69 | b1b2.4 | LEU 35 | - | VdWContact |
| LEU 70 | b1b2.6 | LEU 35 | - | Hydrophobic |
| GLY 73 | b1b2.9 | ARG 37 | - | VdWContact |
| LYS 76 | b1b2.13 | ARG 37 | - | VdWContact |
