Predicted complex interactions
CXCL6_HUMAN + CXCR3
SUMMARY
- Chemokine
- CXCL6_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 153
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm48 | PHE 131 | 3.32x32 | HBDonor |
| GLY 1 | NTc.Cm48 | PHE 131 | 3.32x32 | VdWContact |
| GLY 1 | NTc.Cm48 | PHE 135 | 3.36x36 | VdWContact |
| GLY 1 | NTc.Cm48 | TRP 268 | 6.48x48 | VdWContact |
| PRO 2 | NTc.Cm47 | ASN 132 | 3.33x33 | VdWContact |
| PRO 2 | NTc.Cm47 | GLN 219 | 5.42x43 | Hydrophobic |
| PRO 2 | NTc.Cm47 | GLN 219 | 5.42x43 | VdWContact |
| PRO 2 | NTc.Cm47 | TYR 271 | 6.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TYR 271 | 6.51x51 | VdWContact |
| VAL 3 | NTc.Cm46 | TRP 109 | 2.60x60 | Hydrophobic |
| VAL 3 | NTc.Cm46 | GLY 128 | 3.29x29 | VdWContact |
| VAL 3 | NTc.Cm46 | PHE 131 | 3.32x32 | Hydrophobic |
| VAL 3 | NTc.Cm46 | ASN 132 | 3.33x33 | HBDonor |
| VAL 3 | NTc.Cm46 | ASN 132 | 3.33x33 | VdWContact |
| VAL 3 | NTc.Cm46 | LEU 190 | 4.64x65 | Hydrophobic |
| VAL 3 | NTc.Cm46 | TYR 205 | 45.52x52 | Hydrophobic |
| VAL 3 | NTc.Cm46 | TYR 205 | 45.52x52 | VdWContact |
| SER 4 | NTc.Cm45 | TYR 271 | 6.51x51 | HBAcceptor |
| ALA 5 | NTc.Cm44 | TYR 271 | 6.51x51 | Hydrophobic |
| ALA 5 | NTc.Cm44 | TYR 271 | 6.51x51 | VdWContact |
| ALA 5 | NTc.Cm44 | SER 304 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm44 | TYR 308 | 7.43x42 | Hydrophobic |
| ALA 5 | NTc.Cm44 | TYR 308 | 7.43x42 | VdWContact |
| VAL 6 | NTc.Cm43 | TYR 60 | 1.39x39 | Hydrophobic |
| VAL 6 | NTc.Cm43 | TRP 109 | 2.60x60 | Hydrophobic |
| VAL 6 | NTc.Cm43 | TRP 109 | 2.60x60 | VdWContact |
| VAL 6 | NTc.Cm43 | PHE 131 | 3.32x32 | Hydrophobic |
| VAL 6 | NTc.Cm43 | PHE 131 | 3.32x32 | VdWContact |
| VAL 6 | NTc.Cm43 | TYR 308 | 7.43x42 | Hydrophobic |
| VAL 6 | NTc.Cm43 | TYR 308 | 7.43x42 | VdWContact |
| LEU 7 | NTc.Cm42 | TRP 109 | 2.60x60 | Hydrophobic |
| LEU 7 | NTc.Cm42 | LEU 190 | 4.64x65 | Hydrophobic |
| LEU 7 | NTc.Cm42 | LEU 190 | 4.64x65 | VdWContact |
| LEU 7 | NTc.Cm42 | CYS 203 | 45.50x50 | Hydrophobic |
| LEU 7 | NTc.Cm42 | CYS 203 | 45.50x50 | VdWContact |
| LEU 7 | NTc.Cm42 | TYR 205 | 45.52x52 | Hydrophobic |
| LEU 7 | NTc.Cm42 | TYR 205 | 45.52x52 | VdWContact |
| THR 8 | NTc.Cm41 | LEU 49 | 1.28x28 | Hydrophobic |
| THR 8 | NTc.Cm41 | LEU 198 | - | Hydrophobic |
| THR 8 | NTc.Cm41 | HIS 202 | - | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 212 | 5.35x36 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 212 | 5.35x36 | VdWContact |
| GLU 9 | NTc.Cm40 | ARG 216 | 5.39x40 | Anionic |
| GLU 9 | NTc.Cm40 | ARG 216 | 5.39x40 | HBAcceptor |
| GLU 9 | NTc.Cm40 | ARG 216 | 5.39x40 | VdWContact |
| GLU 9 | NTc.Cm40 | LYS 300 | 7.35x34 | Anionic |
| GLU 9 | NTc.Cm40 | LYS 300 | 7.35x34 | HBAcceptor |
| GLU 9 | NTc.Cm40 | LYS 300 | 7.35x34 | VdWContact |
| LEU 10 | NTc.Cm39 | GLN 45 | 1.24x24 | VdWContact |
| LEU 10 | NTc.Cm39 | LEU 49 | 1.28x28 | Hydrophobic |
| LEU 10 | NTc.Cm39 | ASP 195 | - | VdWContact |
| LEU 10 | NTc.Cm39 | LEU 198 | - | Hydrophobic |
| LEU 10 | NTc.Cm39 | LEU 198 | - | VdWContact |
| ARG 11 | NTc.Cm38 | GLN 45 | 1.24x24 | HBAcceptor |
| ARG 11 | NTc.Cm38 | GLN 45 | 1.24x24 | VdWContact |
| ARG 11 | NTc.Cm38 | ARG 197 | - | HBAcceptor |
| ARG 11 | NTc.Cm38 | ARG 197 | - | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 278 | 6.58x58 | Cationic |
| ARG 11 | NTc.Cm38 | ASP 278 | 6.58x58 | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 278 | 6.58x58 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 282 | 6.62x62 | Cationic |
| ARG 11 | NTc.Cm38 | GLU 293 | 7.28x27 | Cationic |
| ARG 11 | NTc.Cm38 | GLU 293 | 7.28x27 | VdWContact |
| ARG 11 | NTc.Cm38 | ASP 297 | 7.32x31 | Cationic |
| ARG 11 | NTc.Cm38 | ASP 297 | 7.32x31 | HBDonor |
| ARG 11 | NTc.Cm38 | ASP 297 | 7.32x31 | VdWContact |
| CYS 12 | NTc.Cm37 | ARG 288 | - | Anionic |
| CYS 12 | NTc.Cm37 | ARG 288 | - | HBAcceptor |
| CYS 12 | NTc.Cm37 | ARG 288 | - | VdWContact |
| THR 13 | NTc.Cm36 | PRO 42 | - | VdWContact |
| THR 13 | NTc.Cm36 | CYS 43 | - | HBAcceptor |
| THR 13 | NTc.Cm36 | CYS 43 | - | VdWContact |
| THR 13 | NTc.Cm36 | ARG 197 | - | VdWContact |
| LEU 15 | NTc.Cm34 | CYS 43 | - | VdWContact |
| LEU 15 | NTc.Cm34 | ARG 288 | - | Hydrophobic |
| LEU 15 | NTc.Cm34 | ARG 288 | - | VdWContact |
| ARG 16 | NTc.Cm33 | SER 40 | - | VdWContact |
| VAL 17 | NTc.Cm32 | SER 40 | - | VdWContact |
| THR 18 | NTc.Cm31 | THR 39 | - | Hydrophobic |
| THR 18 | NTc.Cm31 | THR 39 | - | VdWContact |
| THR 18 | NTc.Cm31 | SER 40 | - | HBAcceptor |
| THR 18 | NTc.Cm31 | SER 40 | - | VdWContact |
| ARG 20 | NTc.Cm29 | TYR 29 | - | Hydrophobic |
| ARG 20 | NTc.Cm29 | TYR 29 | - | VdWContact |
| PRO 23 | NTc.Cm26 | LEU 20 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | LEU 20 | - | VdWContact |
| PRO 23 | NTc.Cm26 | TYR 29 | - | Hydrophobic |
| ILE 26 | NTc.Cm23 | VAL 16 | - | Hydrophobic |
| GLY 27 | NTc.Cm22 | ASP 13 | - | VdWContact |
| LYS 28 | NTc.Cm21 | VAL 10 | - | Hydrophobic |
| LYS 28 | NTc.Cm21 | VAL 10 | - | VdWContact |
| LYS 28 | NTc.Cm21 | LEU 11 | - | VdWContact |
| LEU 29 | NTc.Cm20 | VAL 10 | - | VdWContact |
| LEU 29 | NTc.Cm20 | LEU 11 | - | HBAcceptor |
| LEU 29 | NTc.Cm20 | LEU 11 | - | HBDonor |
| LEU 29 | NTc.Cm20 | LEU 11 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | LEU 11 | - | VdWContact |
| LEU 29 | NTc.Cm20 | VAL 16 | - | Hydrophobic |
| GLN 30 | NTc.Cm19 | GLN 9 | - | VdWContact |
| GLN 30 | NTc.Cm19 | VAL 10 | - | Hydrophobic |
| VAL 31 | NTc.Cm18 | VAL 5 | - | Hydrophobic |
| VAL 31 | NTc.Cm18 | HIS 8 | - | VdWContact |
| VAL 31 | NTc.Cm18 | GLN 9 | - | HBAcceptor |
| VAL 31 | NTc.Cm18 | GLN 9 | - | HBDonor |
| VAL 31 | NTc.Cm18 | GLN 9 | - | Hydrophobic |
| VAL 31 | NTc.Cm18 | GLN 9 | - | VdWContact |
| PHE 32 | NTc.Cm17 | HIS 8 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | HIS 8 | - | VdWContact |
| PHE 32 | NTc.Cm17 | ARG 197 | - | Hydrophobic |
| PHE 32 | NTc.Cm17 | ARG 197 | - | VdWContact |
| PRO 33 | NTc.Cm16 | VAL 5 | - | Hydrophobic |
| PRO 33 | NTc.Cm16 | VAL 5 | - | VdWContact |
| PRO 33 | NTc.Cm16 | HIS 8 | - | VdWContact |
| PRO 36 | NTc.Cm13 | TYR 205 | 45.52x52 | VdWContact |
| GLN 37 | NTc.Cm12 | GLN 204 | 45.51x51 | HBDonor |
| GLN 37 | NTc.Cm12 | GLN 204 | 45.51x51 | VdWContact |
| GLN 37 | NTc.Cm12 | ARG 212 | 5.35x36 | HBAcceptor |
| GLN 37 | NTc.Cm12 | ARG 212 | 5.35x36 | VdWContact |
| GLU 42 | NTc.Cm7 | ARG 197 | - | Anionic |
| GLU 42 | NTc.Cm7 | ARG 197 | - | HBAcceptor |
| GLU 42 | NTc.Cm7 | ARG 197 | - | VdWContact |
| VAL 44 | NTc.Cm5 | PRO 42 | - | Hydrophobic |
| LYS 48 | NTc.Cm1 | ASP 13 | - | Cationic |
| LYS 48 | NTc.Cm1 | ASP 13 | - | HBDonor |
| LYS 48 | NTc.Cm1 | ASP 13 | - | VdWContact |
| GLN 52 | cxb1.1 | PRO 41 | - | VdWContact |
| GLN 52 | cxb1.1 | PRO 42 | - | Hydrophobic |
| VAL 53 | cxb1.2 | THR 39 | - | Hydrophobic |
| VAL 53 | cxb1.2 | PRO 41 | - | VdWContact |
| CYS 54 | cxb1.5 | SER 40 | - | HBDonor |
| CYS 54 | cxb1.5 | SER 40 | - | VdWContact |
| PRO 60 | cxb1.15 | PHE 23 | - | VdWContact |
| PRO 60 | cxb1.15 | TYR 27 | - | Hydrophobic |
| PRO 60 | cxb1.15 | TYR 27 | - | VdWContact |
| PHE 61 | cxb1.16 | LEU 20 | - | Hydrophobic |
| PHE 61 | cxb1.16 | PHE 23 | - | Hydrophobic |
| PHE 61 | cxb1.16 | PHE 23 | - | VdWContact |
| LYS 63 | B1.2 | LEU 3 | - | Hydrophobic |
| LYS 64 | B1.3 | PHE 23 | - | Hydrophobic |
| LYS 64 | B1.3 | PHE 23 | - | VdWContact |
| VAL 65 | B1.4 | LEU 11 | - | Hydrophobic |
| VAL 65 | B1.4 | LEU 19 | - | Hydrophobic |
| VAL 65 | B1.4 | LEU 19 | - | VdWContact |
| ILE 66 | B1.5 | LEU 3 | - | Hydrophobic |
| ILE 66 | B1.5 | VAL 5 | - | Hydrophobic |
| ILE 66 | B1.5 | VAL 5 | - | VdWContact |
| LYS 68 | B1.7 | LEU 19 | - | Hydrophobic |
| ILE 69 | b1b2.4 | GLN 9 | - | Hydrophobic |
| ILE 69 | b1b2.4 | GLN 9 | - | VdWContact |
| ILE 69 | b1b2.4 | LEU 11 | - | Hydrophobic |
| ILE 69 | b1b2.4 | LEU 11 | - | VdWContact |
| LEU 70 | b1b2.6 | GLU 4 | - | VdWContact |
| LEU 70 | b1b2.6 | VAL 5 | - | VdWContact |
