Predicted complex interactions
CXCL7_HUMAN + CXCR3
SUMMARY
- Chemokine
- CXCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR3 View partner entry
- Partner description
- UniProt: P49682; Gene: cxcr3_human; Family: Chemokine
- Interactions detected
- 142
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASP 22 | NTc.Cm41 | ARG 53 | 1.32x32 | Anionic |
| ASP 22 | NTc.Cm41 | ARG 53 | 1.32x32 | HBAcceptor |
| ASP 22 | NTc.Cm41 | ARG 53 | 1.32x32 | VdWContact |
| ASP 22 | NTc.Cm41 | LEU 198 | - | Hydrophobic |
| ASP 22 | NTc.Cm41 | LEU 198 | - | VdWContact |
| ASP 22 | NTc.Cm41 | ALA 200 | - | Hydrophobic |
| LEU 23 | NTc.Cm40 | GLN 45 | 1.24x24 | Hydrophobic |
| LEU 23 | NTc.Cm40 | GLN 45 | 1.24x24 | VdWContact |
| LEU 23 | NTc.Cm40 | ASP 46 | 1.25x25 | Hydrophobic |
| LEU 23 | NTc.Cm40 | ASP 46 | 1.25x25 | VdWContact |
| LEU 23 | NTc.Cm40 | LEU 49 | 1.28x28 | Hydrophobic |
| LEU 23 | NTc.Cm40 | LEU 49 | 1.28x28 | VdWContact |
| LEU 23 | NTc.Cm40 | LEU 198 | - | Hydrophobic |
| LEU 23 | NTc.Cm40 | LEU 198 | - | VdWContact |
| TYR 24 | NTc.Cm39 | LEU 49 | 1.28x28 | Hydrophobic |
| TYR 24 | NTc.Cm39 | LEU 49 | 1.28x28 | VdWContact |
| TYR 24 | NTc.Cm39 | ARG 53 | 1.32x32 | Hydrophobic |
| TYR 24 | NTc.Cm39 | ARG 53 | 1.32x32 | VdWContact |
| TYR 24 | NTc.Cm39 | ASP 112 | 2.63x63 | HBDonor |
| TYR 24 | NTc.Cm39 | ASP 112 | 2.63x63 | VdWContact |
| TYR 24 | NTc.Cm39 | ALA 113 | 2.64x64 | VdWContact |
| TYR 24 | NTc.Cm39 | VAL 115 | 2.66x66 | VdWContact |
| TYR 24 | NTc.Cm39 | HIS 202 | - | Hydrophobic |
| TYR 24 | NTc.Cm39 | HIS 202 | - | VdWContact |
| ALA 25 | NTc.Cm38 | GLN 45 | 1.24x24 | Hydrophobic |
| ALA 25 | NTc.Cm38 | LEU 49 | 1.28x28 | Hydrophobic |
| ALA 25 | NTc.Cm38 | LEU 49 | 1.28x28 | VdWContact |
| GLU 26 | NTc.Cm37 | LYS 300 | 7.35x34 | Anionic |
| GLU 26 | NTc.Cm37 | LYS 300 | 7.35x34 | HBAcceptor |
| GLU 26 | NTc.Cm37 | LYS 300 | 7.35x34 | VdWContact |
| LEU 27 | NTc.Cm36 | ASP 195 | - | Hydrophobic |
| LEU 27 | NTc.Cm36 | ASP 195 | - | VdWContact |
| LEU 27 | NTc.Cm36 | ARG 197 | - | Hydrophobic |
| LEU 27 | NTc.Cm36 | LEU 198 | - | Hydrophobic |
| LEU 27 | NTc.Cm36 | LEU 198 | - | VdWContact |
| LEU 27 | NTc.Cm36 | GLN 204 | 45.51x51 | VdWContact |
| ARG 28 | NTc.Cm35 | GLN 45 | 1.24x24 | VdWContact |
| ARG 28 | NTc.Cm35 | ARG 197 | - | HBAcceptor |
| ARG 28 | NTc.Cm35 | ARG 197 | - | VdWContact |
| ARG 28 | NTc.Cm35 | ASP 278 | 6.58x58 | Cationic |
| ARG 28 | NTc.Cm35 | ASP 278 | 6.58x58 | HBDonor |
| ARG 28 | NTc.Cm35 | ASP 278 | 6.58x58 | VdWContact |
| ARG 28 | NTc.Cm35 | GLU 293 | 7.28x27 | Cationic |
| ARG 28 | NTc.Cm35 | GLU 293 | 7.28x27 | VdWContact |
| ARG 28 | NTc.Cm35 | ASP 297 | 7.32x31 | Cationic |
| ARG 28 | NTc.Cm35 | ASP 297 | 7.32x31 | HBDonor |
| ARG 28 | NTc.Cm35 | ASP 297 | 7.32x31 | VdWContact |
| ARG 28 | NTc.Cm35 | LYS 300 | 7.35x34 | VdWContact |
| CYS 29 | NTc.Cm34 | ARG 288 | - | Anionic |
| CYS 29 | NTc.Cm34 | ARG 288 | - | HBAcceptor |
| CYS 29 | NTc.Cm34 | ARG 288 | - | VdWContact |
| MET 30 | NTc.Cm33 | PRO 42 | - | Hydrophobic |
| MET 30 | NTc.Cm33 | PRO 42 | - | VdWContact |
| MET 30 | NTc.Cm33 | CYS 43 | - | HBAcceptor |
| MET 30 | NTc.Cm33 | CYS 43 | - | VdWContact |
| MET 30 | NTc.Cm33 | GLN 45 | 1.24x24 | Hydrophobic |
| MET 30 | NTc.Cm33 | ARG 197 | - | VdWContact |
| CYS 31 | NTc.Cm32 | ARG 288 | - | HBAcceptor |
| ILE 32 | NTc.Cm31 | CYS 43 | - | VdWContact |
| ILE 32 | NTc.Cm31 | ARG 288 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | ARG 288 | - | VdWContact |
| ILE 32 | NTc.Cm31 | CYS 290 | 7.25x24 | VdWContact |
| LYS 33 | NTc.Cm30 | SER 40 | - | VdWContact |
| THR 35 | NTc.Cm28 | SER 40 | - | HBAcceptor |
| THR 35 | NTc.Cm28 | SER 40 | - | VdWContact |
| HIS 39 | NTc.Cm24 | TYR 29 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | TYR 29 | - | VdWContact |
| PRO 40 | NTc.Cm23 | LEU 20 | - | Hydrophobic |
| PRO 40 | NTc.Cm23 | LEU 20 | - | VdWContact |
| PRO 40 | NTc.Cm23 | TYR 29 | - | VdWContact |
| ILE 43 | NTc.Cm20 | VAL 16 | - | Hydrophobic |
| ILE 43 | NTc.Cm20 | LEU 20 | - | Hydrophobic |
| GLN 44 | NTc.Cm19 | ASP 13 | - | HBAcceptor |
| GLN 44 | NTc.Cm19 | ASP 13 | - | VdWContact |
| SER 45 | NTc.Cm18 | LEU 11 | - | VdWContact |
| LEU 46 | NTc.Cm17 | VAL 10 | - | VdWContact |
| LEU 46 | NTc.Cm17 | LEU 11 | - | HBAcceptor |
| LEU 46 | NTc.Cm17 | LEU 11 | - | HBDonor |
| LEU 46 | NTc.Cm17 | LEU 11 | - | Hydrophobic |
| LEU 46 | NTc.Cm17 | LEU 11 | - | VdWContact |
| LEU 46 | NTc.Cm17 | VAL 16 | - | Hydrophobic |
| GLU 47 | NTc.Cm16 | HIS 8 | - | HBAcceptor |
| GLU 47 | NTc.Cm16 | HIS 8 | - | Hydrophobic |
| GLU 47 | NTc.Cm16 | HIS 8 | - | VdWContact |
| GLU 47 | NTc.Cm16 | GLN 9 | - | VdWContact |
| GLU 47 | NTc.Cm16 | VAL 10 | - | Hydrophobic |
| VAL 48 | NTc.Cm15 | VAL 5 | - | Hydrophobic |
| VAL 48 | NTc.Cm15 | HIS 8 | - | VdWContact |
| VAL 48 | NTc.Cm15 | GLN 9 | - | HBAcceptor |
| VAL 48 | NTc.Cm15 | GLN 9 | - | HBDonor |
| VAL 48 | NTc.Cm15 | GLN 9 | - | VdWContact |
| VAL 48 | NTc.Cm15 | LEU 11 | - | Hydrophobic |
| ILE 49 | NTc.Cm14 | ASP 7 | - | VdWContact |
| ILE 49 | NTc.Cm14 | HIS 8 | - | Hydrophobic |
| ILE 49 | NTc.Cm14 | HIS 8 | - | VdWContact |
| ILE 49 | NTc.Cm14 | ARG 197 | - | Hydrophobic |
| ILE 49 | NTc.Cm14 | ARG 197 | - | VdWContact |
| GLY 50 | NTc.Cm13 | ASP 7 | - | HBDonor |
| GLY 50 | NTc.Cm13 | ASP 7 | - | VdWContact |
| HIS 54 | NTc.Cm9 | GLN 204 | 45.51x51 | HBDonor |
| HIS 54 | NTc.Cm9 | GLN 204 | 45.51x51 | VdWContact |
| HIS 54 | NTc.Cm9 | ARG 212 | 5.35x36 | HBAcceptor |
| HIS 54 | NTc.Cm9 | ARG 212 | 5.35x36 | VdWContact |
| VAL 58 | NTc.Cm5 | VAL 5 | - | Hydrophobic |
| GLU 59 | NTc.Cm4 | ARG 197 | - | Anionic |
| ILE 61 | NTc.Cm2 | PRO 42 | - | Hydrophobic |
| LYS 65 | CX.5 | ASP 13 | - | Cationic |
| LYS 65 | CX.5 | ASP 13 | - | HBDonor |
| LYS 65 | CX.5 | ASP 13 | - | VdWContact |
| ARG 68 | cxb1.5 | ASP 35 | - | Cationic |
| ARG 68 | cxb1.5 | ASP 35 | - | HBDonor |
| ARG 68 | cxb1.5 | ASP 35 | - | VdWContact |
| ARG 68 | cxb1.5 | THR 39 | - | VdWContact |
| LYS 69 | cxb1.6 | PRO 41 | - | VdWContact |
| LYS 69 | cxb1.6 | PRO 42 | - | Hydrophobic |
| CYS 71 | cxb1.10 | SER 40 | - | HBDonor |
| CYS 71 | cxb1.10 | SER 40 | - | VdWContact |
| ARG 78 | B1.3 | TYR 27 | - | VdWContact |
| ARG 78 | B1.3 | TYR 29 | - | VdWContact |
| LYS 81 | B1.6 | PHE 23 | - | Hydrophobic |
| LYS 81 | B1.6 | PHE 23 | - | VdWContact |
| ILE 82 | B1.7 | LEU 11 | - | Hydrophobic |
| ILE 82 | B1.7 | LEU 11 | - | VdWContact |
| ILE 82 | B1.7 | LEU 19 | - | Hydrophobic |
| ILE 82 | B1.7 | LEU 19 | - | VdWContact |
| ILE 82 | B1.7 | LEU 20 | - | Hydrophobic |
| ILE 82 | B1.7 | LEU 20 | - | VdWContact |
| VAL 83 | b1b2.4 | VAL 5 | - | Hydrophobic |
| GLN 84 | b1b2.6 | LEU 3 | - | Hydrophobic |
| LYS 85 | b1b2.7 | LEU 19 | - | Hydrophobic |
| LYS 85 | b1b2.7 | LEU 19 | - | VdWContact |
| LYS 86 | b1b2.8 | GLN 9 | - | VdWContact |
| LYS 86 | b1b2.8 | LEU 11 | - | Hydrophobic |
| LYS 86 | b1b2.8 | LEU 11 | - | VdWContact |
| LYS 86 | b1b2.8 | GLU 15 | - | Cationic |
| LYS 86 | b1b2.8 | GLU 15 | - | HBDonor |
| LYS 86 | b1b2.8 | GLU 15 | - | VdWContact |
| LEU 87 | b1b2.9 | LEU 3 | - | Hydrophobic |
| LEU 87 | b1b2.9 | LEU 3 | - | VdWContact |
| LEU 87 | b1b2.9 | VAL 5 | - | Hydrophobic |
| LEU 87 | b1b2.9 | VAL 5 | - | VdWContact |
| ASP 90 | b1b2.13 | GLN 9 | - | VdWContact |
