Predicted complex interactions
CCL11_HUMAN + CXCR4
SUMMARY
- Chemokine
- CCL11_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 66
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm31 | TYR 116 | 3.32x32 | VdWContact |
| GLY 1 | NTc.Cm31 | GLU 288 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm31 | GLU 288 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm31 | GLU 288 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm30 | TYR 45 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm30 | TYR 45 | 1.39x39 | VdWContact |
| PRO 2 | NTc.Cm30 | TRP 94 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm30 | TRP 94 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm30 | GLU 288 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm30 | PHE 292 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm30 | PHE 292 | 7.43x42 | VdWContact |
| VAL 5 | NTc.Cm27 | ARG 30 | 1.24x24 | Hydrophobic |
| PRO 6 | NTc.Cm26 | ARG 30 | 1.24x24 | VdWContact |
| THR 7 | NTc.Cm25 | ARG 30 | 1.24x24 | HBAcceptor |
| THR 7 | NTc.Cm25 | ARG 30 | 1.24x24 | VdWContact |
| THR 7 | NTc.Cm25 | GLU 31 | 1.25x25 | Hydrophobic |
| THR 7 | NTc.Cm25 | ALA 34 | 1.28x28 | Hydrophobic |
| THR 7 | NTc.Cm25 | ASP 181 | - | HBDonor |
| THR 7 | NTc.Cm25 | ASP 181 | - | VdWContact |
| THR 8 | NTc.Cm24 | PRO 27 | - | Hydrophobic |
| THR 8 | NTc.Cm24 | PRO 27 | - | VdWContact |
| THR 8 | NTc.Cm24 | CYS 28 | - | VdWContact |
| THR 8 | NTc.Cm24 | PHE 29 | - | Hydrophobic |
| CYS 9 | NTc.Cm23 | CYS 28 | - | HBAcceptor |
| CYS 9 | NTc.Cm23 | CYS 28 | - | HBDonor |
| CYS 9 | NTc.Cm23 | CYS 28 | - | VdWContact |
| CYS 9 | NTc.Cm23 | ARG 30 | 1.24x24 | Anionic |
| PHE 11 | NTc.Cm21 | CYS 28 | - | Hydrophobic |
| PHE 11 | NTc.Cm21 | ARG 30 | 1.24x24 | VdWContact |
| PHE 11 | NTc.Cm21 | GLU 277 | 7.28x27 | VdWContact |
| ASN 12 | NTc.Cm20 | LYS 25 | - | HBAcceptor |
| ASN 12 | NTc.Cm20 | LYS 25 | - | Hydrophobic |
| ASN 12 | NTc.Cm20 | LYS 25 | - | VdWContact |
| LEU 13 | NTc.Cm19 | LYS 25 | - | VdWContact |
| ARG 16 | NTc.Cm16 | ASP 20 | - | Cationic |
| ARG 16 | NTc.Cm16 | ASP 20 | - | HBDonor |
| ARG 16 | NTc.Cm16 | ASP 20 | - | VdWContact |
| ILE 18 | NTc.Cm14 | MET 24 | - | Hydrophobic |
| PRO 19 | NTc.Cm13 | MET 16 | - | Hydrophobic |
| ARG 22 | NTc.Cm10 | MET 16 | - | VdWContact |
| ARG 22 | NTc.Cm10 | TYR 21 | - | HBDonor |
| ARG 22 | NTc.Cm10 | TYR 21 | - | VdWContact |
| ARG 27 | NTc.Cm5 | PHE 29 | - | VdWContact |
| ARG 27 | NTc.Cm5 | ASP 181 | - | Cationic |
| THR 30 | NTc.Cm2 | GLU 179 | - | HBDonor |
| GLY 32 | CX.1 | PHE 189 | - | VdWContact |
| LYS 33 | CX.5 | ILE 185 | - | Hydrophobic |
| LYS 33 | CX.5 | ILE 185 | - | VdWContact |
| LYS 33 | CX.5 | ASP 187 | 45.51x51 | Cationic |
| LYS 33 | CX.5 | ASP 187 | 45.51x51 | HBDonor |
| LYS 33 | CX.5 | ASP 187 | 45.51x51 | VdWContact |
| PRO 35 | cxb1.2 | ASP 193 | 5.32x33 | VdWContact |
| PRO 35 | cxb1.2 | LEU 266 | 6.62x62 | Hydrophobic |
| ILE 40 | cxb1.10 | PRO 27 | - | Hydrophobic |
| LEU 45 | B1.1 | TYR 21 | - | Hydrophobic |
| LYS 47 | B1.3 | TYR 21 | - | Hydrophobic |
| LYS 47 | B1.3 | GLU 26 | - | Cationic |
| ASP 48 | B1.4 | GLU 26 | - | VdWContact |
| ASP 48 | B1.4 | PRO 27 | - | Hydrophobic |
| ASP 48 | B1.4 | PRO 27 | - | VdWContact |
| ASP 48 | B1.4 | PHE 29 | - | Hydrophobic |
| ILE 49 | B1.5 | MET 24 | - | Hydrophobic |
| ILE 49 | B1.5 | MET 24 | - | VdWContact |
| CYS 50 | B1.6 | LYS 25 | - | HBDonor |
| CYS 50 | B1.6 | LYS 25 | - | VdWContact |
| CYS 50 | B1.6 | PRO 27 | - | VdWContact |
