Predicted complex interactions
CCL13_HUMAN + CXCR4
SUMMARY
- Chemokine
- CCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 96
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PRO 3 | NTc.Cm31 | PHE 189 | - | VdWContact |
| PRO 3 | NTc.Cm31 | TYR 190 | - | VdWContact |
| PRO 3 | NTc.Cm31 | PRO 191 | - | VdWContact |
| GLN 4 | NTc.Cm30 | PHE 189 | - | Hydrophobic |
| GLN 4 | NTc.Cm30 | PHE 189 | - | VdWContact |
| GLY 5 | NTc.Cm29 | ASP 187 | 45.51x51 | VdWContact |
| GLY 5 | NTc.Cm29 | ARG 188 | 45.52x52 | VdWContact |
| GLY 5 | NTc.Cm29 | PHE 189 | - | VdWContact |
| GLY 5 | NTc.Cm29 | TYR 190 | - | VdWContact |
| LEU 6 | NTc.Cm28 | ASP 187 | 45.51x51 | Hydrophobic |
| LEU 6 | NTc.Cm28 | ASP 187 | 45.51x51 | VdWContact |
| ALA 7 | NTc.Cm27 | HIS 113 | 3.29x29 | Hydrophobic |
| ALA 7 | NTc.Cm27 | ASP 187 | 45.51x51 | HBDonor |
| ALA 7 | NTc.Cm27 | ASP 187 | 45.51x51 | VdWContact |
| ALA 7 | NTc.Cm27 | ARG 188 | 45.52x52 | HBAcceptor |
| ALA 7 | NTc.Cm27 | ARG 188 | 45.52x52 | Hydrophobic |
| ALA 7 | NTc.Cm27 | ARG 188 | 45.52x52 | VdWContact |
| GLN 8 | NTc.Cm26 | TRP 94 | 2.60x60 | Hydrophobic |
| GLN 8 | NTc.Cm26 | HIS 113 | 3.29x29 | Hydrophobic |
| GLN 8 | NTc.Cm26 | HIS 113 | 3.29x29 | VdWContact |
| GLN 8 | NTc.Cm26 | ASP 187 | 45.51x51 | HBDonor |
| GLN 8 | NTc.Cm26 | ASP 187 | 45.51x51 | VdWContact |
| PRO 9 | NTc.Cm25 | TRP 94 | 2.60x60 | Hydrophobic |
| PRO 9 | NTc.Cm25 | GLU 288 | 7.39x38 | VdWContact |
| PRO 9 | NTc.Cm25 | PHE 292 | 7.43x42 | Hydrophobic |
| ASP 10 | NTc.Cm24 | TYR 255 | 6.51x51 | HBAcceptor |
| ASP 10 | NTc.Cm24 | TYR 255 | 6.51x51 | Hydrophobic |
| ASP 10 | NTc.Cm24 | TYR 255 | 6.51x51 | VdWContact |
| ASP 10 | NTc.Cm24 | ILE 259 | 6.55x55 | Hydrophobic |
| ASP 10 | NTc.Cm24 | ILE 284 | 7.35x34 | Hydrophobic |
| ASP 10 | NTc.Cm24 | GLU 288 | 7.39x38 | HBDonor |
| ASP 10 | NTc.Cm24 | GLU 288 | 7.39x38 | VdWContact |
| ALA 11 | NTc.Cm23 | ASN 37 | 1.31x31 | HBAcceptor |
| ALA 11 | NTc.Cm23 | ASN 37 | 1.31x31 | VdWContact |
| ALA 11 | NTc.Cm23 | LEU 41 | 1.35x35 | Hydrophobic |
| ALA 11 | NTc.Cm23 | SER 285 | 7.36x35 | VdWContact |
| ALA 11 | NTc.Cm23 | GLU 288 | 7.39x38 | HBDonor |
| ALA 11 | NTc.Cm23 | GLU 288 | 7.39x38 | VdWContact |
| LEU 12 | NTc.Cm22 | LEU 41 | 1.35x35 | Hydrophobic |
| LEU 12 | NTc.Cm22 | TYR 45 | 1.39x39 | Hydrophobic |
| LEU 12 | NTc.Cm22 | TRP 94 | 2.60x60 | Hydrophobic |
| LEU 12 | NTc.Cm22 | TRP 94 | 2.60x60 | VdWContact |
| LEU 12 | NTc.Cm22 | ALA 98 | 2.64x64 | Hydrophobic |
| LEU 12 | NTc.Cm22 | ALA 98 | 2.64x64 | VdWContact |
| VAL 14 | NTc.Cm20 | ILE 185 | - | Hydrophobic |
| VAL 14 | NTc.Cm20 | ILE 185 | - | VdWContact |
| PRO 15 | NTc.Cm19 | ARG 30 | 1.24x24 | Hydrophobic |
| PRO 15 | NTc.Cm19 | ARG 30 | 1.24x24 | VdWContact |
| PRO 15 | NTc.Cm19 | ALA 34 | 1.28x28 | Hydrophobic |
| PRO 15 | NTc.Cm19 | ALA 34 | 1.28x28 | VdWContact |
| THR 17 | NTc.Cm17 | PRO 27 | - | Hydrophobic |
| THR 17 | NTc.Cm17 | PRO 27 | - | VdWContact |
| THR 17 | NTc.Cm17 | CYS 28 | - | VdWContact |
| THR 17 | NTc.Cm17 | PHE 29 | - | Hydrophobic |
| CYS 18 | NTc.Cm16 | CYS 28 | - | HBAcceptor |
| CYS 18 | NTc.Cm16 | CYS 28 | - | HBDonor |
| CYS 18 | NTc.Cm16 | CYS 28 | - | VdWContact |
| CYS 18 | NTc.Cm16 | ARG 30 | 1.24x24 | Anionic |
| PHE 20 | NTc.Cm14 | CYS 28 | - | Hydrophobic |
| PHE 20 | NTc.Cm14 | CYS 28 | - | VdWContact |
| PHE 20 | NTc.Cm14 | CYS 274 | 7.25x24 | Hydrophobic |
| PHE 20 | NTc.Cm14 | GLU 277 | 7.28x27 | Hydrophobic |
| PHE 20 | NTc.Cm14 | GLU 277 | 7.28x27 | VdWContact |
| SER 23 | NTc.Cm11 | SER 23 | - | VdWContact |
| SER 23 | NTc.Cm11 | MET 24 | - | VdWContact |
| SER 23 | NTc.Cm11 | LYS 25 | - | HBAcceptor |
| SER 23 | NTc.Cm11 | LYS 25 | - | VdWContact |
| SER 24 | NTc.Cm10 | SER 23 | - | HBDonor |
| SER 24 | NTc.Cm10 | SER 23 | - | VdWContact |
| LYS 25 | NTc.Cm9 | ASP 20 | - | Cationic |
| LYS 25 | NTc.Cm9 | ASP 20 | - | HBDonor |
| LYS 25 | NTc.Cm9 | ASP 20 | - | VdWContact |
| ILE 27 | NTc.Cm7 | MET 24 | - | Hydrophobic |
| ARG 31 | NTc.Cm3 | GLU 14 | - | Cationic |
| ARG 31 | NTc.Cm3 | GLU 14 | - | HBDonor |
| ARG 31 | NTc.Cm3 | GLU 14 | - | VdWContact |
| ARG 31 | NTc.Cm3 | MET 16 | - | VdWContact |
| SER 40 | cxb1.7 | ASP 193 | 5.32x33 | VdWContact |
| ARG 41 | cxb1.8 | LEU 266 | 6.62x62 | VdWContact |
| PRO 43 | cxb1.11 | ILE 265 | 6.61x61 | Hydrophobic |
| PRO 43 | cxb1.11 | ILE 265 | 6.61x61 | VdWContact |
| GLN 44 | cxb1.14 | GLU 268 | 6.64x64 | HBDonor |
| GLN 44 | cxb1.14 | GLU 268 | 6.64x64 | VdWContact |
| ILE 48 | B1.2 | PRO 27 | - | Hydrophobic |
| LYS 55 | b1b2.6 | TYR 21 | - | VdWContact |
| LYS 55 | b1b2.6 | GLU 26 | - | Cationic |
| LYS 55 | b1b2.6 | GLU 26 | - | VdWContact |
| GLU 56 | b1b2.9 | GLU 26 | - | VdWContact |
| GLU 56 | b1b2.9 | PRO 27 | - | Hydrophobic |
| GLU 56 | b1b2.9 | PHE 29 | - | Hydrophobic |
| ILE 57 | b1b2.10 | MET 24 | - | Hydrophobic |
| ILE 57 | b1b2.10 | MET 24 | - | VdWContact |
| CYS 58 | b1b2.12 | LYS 25 | - | HBDonor |
| CYS 58 | b1b2.12 | LYS 25 | - | Hydrophobic |
| CYS 58 | b1b2.12 | LYS 25 | - | VdWContact |
| CYS 58 | b1b2.12 | PRO 27 | - | VdWContact |
