Predicted complex interactions
CCL14_HUMAN + CXCR4
SUMMARY
- Chemokine
- CCL14_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 93
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 5 | NTc.Cm30 | GLU 179 | - | VdWContact |
| SER 5 | NTc.Cm30 | ALA 180 | - | VdWContact |
| SER 5 | NTc.Cm30 | ASP 181 | - | HBAcceptor |
| SER 5 | NTc.Cm30 | ASP 181 | - | VdWContact |
| SER 6 | NTc.Cm29 | GLU 179 | - | VdWContact |
| SER 6 | NTc.Cm29 | ALA 180 | - | VdWContact |
| SER 6 | NTc.Cm29 | ASP 181 | - | VdWContact |
| SER 7 | NTc.Cm28 | SER 178 | - | VdWContact |
| SER 7 | NTc.Cm28 | GLU 179 | - | HBDonor |
| SER 7 | NTc.Cm28 | GLU 179 | - | VdWContact |
| SER 7 | NTc.Cm28 | ALA 180 | - | VdWContact |
| SER 7 | NTc.Cm28 | ARG 183 | - | HBDonor |
| SER 7 | NTc.Cm28 | ARG 183 | - | VdWContact |
| SER 7 | NTc.Cm28 | ILE 185 | - | HBAcceptor |
| SER 7 | NTc.Cm28 | ILE 185 | - | VdWContact |
| SER 7 | NTc.Cm28 | PHE 189 | - | VdWContact |
| ARG 8 | NTc.Cm27 | ALA 180 | - | Hydrophobic |
| ARG 8 | NTc.Cm27 | ALA 180 | - | VdWContact |
| ARG 8 | NTc.Cm27 | ASP 181 | - | Cationic |
| ARG 8 | NTc.Cm27 | ASP 181 | - | VdWContact |
| ARG 8 | NTc.Cm27 | ARG 183 | - | Hydrophobic |
| ARG 8 | NTc.Cm27 | ILE 185 | - | VdWContact |
| GLY 9 | NTc.Cm26 | ASP 97 | 2.63x63 | VdWContact |
| GLY 9 | NTc.Cm26 | ILE 185 | - | VdWContact |
| PRO 10 | NTc.Cm25 | ASP 97 | 2.63x63 | VdWContact |
| PRO 10 | NTc.Cm25 | ASP 187 | 45.51x51 | Hydrophobic |
| TYR 11 | NTc.Cm24 | ASN 37 | 1.31x31 | Hydrophobic |
| TYR 11 | NTc.Cm24 | ASN 37 | 1.31x31 | VdWContact |
| TYR 11 | NTc.Cm24 | LEU 41 | 1.35x35 | Hydrophobic |
| TYR 11 | NTc.Cm24 | SER 285 | 7.36x35 | VdWContact |
| TYR 11 | NTc.Cm24 | GLU 288 | 7.39x38 | HBDonor |
| TYR 11 | NTc.Cm24 | GLU 288 | 7.39x38 | VdWContact |
| HIS 12 | NTc.Cm23 | LYS 38 | 1.32x32 | Hydrophobic |
| HIS 12 | NTc.Cm23 | LYS 38 | 1.32x32 | VdWContact |
| HIS 12 | NTc.Cm23 | ALA 100 | 2.66x66 | HBDonor |
| HIS 12 | NTc.Cm23 | ALA 100 | 2.66x66 | VdWContact |
| HIS 12 | NTc.Cm23 | ARG 183 | - | VdWContact |
| HIS 12 | NTc.Cm23 | ILE 185 | - | Hydrophobic |
| PRO 13 | NTc.Cm22 | ARG 30 | 1.24x24 | Hydrophobic |
| PRO 13 | NTc.Cm22 | ARG 30 | 1.24x24 | VdWContact |
| PRO 13 | NTc.Cm22 | GLU 31 | 1.25x25 | Hydrophobic |
| PRO 13 | NTc.Cm22 | GLU 31 | 1.25x25 | VdWContact |
| PRO 13 | NTc.Cm22 | ALA 34 | 1.28x28 | Hydrophobic |
| PRO 13 | NTc.Cm22 | ALA 34 | 1.28x28 | VdWContact |
| GLU 15 | NTc.Cm20 | PRO 27 | - | Hydrophobic |
| GLU 15 | NTc.Cm20 | PRO 27 | - | VdWContact |
| GLU 15 | NTc.Cm20 | PHE 29 | - | Hydrophobic |
| GLU 15 | NTc.Cm20 | PHE 29 | - | VdWContact |
| PHE 18 | NTc.Cm17 | ASP 193 | 5.32x33 | VdWContact |
| THR 19 | NTc.Cm16 | LYS 25 | - | VdWContact |
| TYR 20 | NTc.Cm15 | LYS 25 | - | HBAcceptor |
| TYR 20 | NTc.Cm15 | LYS 25 | - | VdWContact |
| THR 21 | NTc.Cm14 | SER 23 | - | HBDonor |
| THR 21 | NTc.Cm14 | SER 23 | - | VdWContact |
| THR 21 | NTc.Cm14 | LYS 25 | - | VdWContact |
| TYR 23 | NTc.Cm12 | SER 23 | - | VdWContact |
| ILE 25 | NTc.Cm10 | MET 24 | - | Hydrophobic |
| ILE 25 | NTc.Cm10 | MET 24 | - | VdWContact |
| PRO 26 | NTc.Cm9 | TYR 21 | - | Hydrophobic |
| PRO 26 | NTc.Cm9 | TYR 21 | - | VdWContact |
| ARG 29 | NTc.Cm6 | TYR 21 | - | CationPi |
| ARG 29 | NTc.Cm6 | TYR 21 | - | HBDonor |
| ARG 29 | NTc.Cm6 | TYR 21 | - | Hydrophobic |
| ARG 29 | NTc.Cm6 | TYR 21 | - | VdWContact |
| ARG 29 | NTc.Cm6 | MET 24 | - | Hydrophobic |
| ARG 29 | NTc.Cm6 | MET 24 | - | VdWContact |
| ASN 37 | cxb1.1 | ASP 181 | - | HBDonor |
| ASN 37 | cxb1.1 | ASP 181 | - | VdWContact |
| GLN 39 | cxb1.5 | SER 178 | - | VdWContact |
| GLN 39 | cxb1.5 | GLU 179 | - | VdWContact |
| GLN 39 | cxb1.5 | PHE 189 | - | Hydrophobic |
| SER 41 | cxb1.7 | TYR 190 | - | VdWContact |
| LYS 42 | cxb1.8 | ASP 193 | 5.32x33 | Cationic |
| LYS 42 | cxb1.8 | ASP 193 | 5.32x33 | VdWContact |
| VAL 46 | cxb1.15 | PRO 27 | - | Hydrophobic |
| VAL 46 | cxb1.15 | PRO 27 | - | VdWContact |
| THR 49 | B1.2 | MET 24 | - | Hydrophobic |
| THR 49 | B1.2 | MET 24 | - | VdWContact |
| HIS 53 | B1.6 | GLU 26 | - | HBDonor |
| HIS 53 | B1.6 | GLU 26 | - | Hydrophobic |
| HIS 53 | B1.6 | GLU 26 | - | VdWContact |
| SER 54 | B1.7 | GLU 26 | - | VdWContact |
| SER 54 | B1.7 | PRO 27 | - | VdWContact |
| SER 54 | B1.7 | PHE 29 | - | VdWContact |
| VAL 55 | b1b2.4 | MET 24 | - | Hydrophobic |
| VAL 55 | b1b2.4 | MET 24 | - | VdWContact |
| VAL 55 | b1b2.4 | LYS 25 | - | Hydrophobic |
| VAL 55 | b1b2.4 | LYS 25 | - | VdWContact |
| VAL 55 | b1b2.4 | GLU 26 | - | VdWContact |
| VAL 55 | b1b2.4 | PRO 27 | - | VdWContact |
| CYS 56 | b1b2.6 | LYS 25 | - | HBDonor |
| CYS 56 | b1b2.6 | LYS 25 | - | VdWContact |
| CYS 56 | b1b2.6 | PRO 27 | - | VdWContact |
