Predicted complex interactions
CXCL7_HUMAN + ACKR2
SUMMARY
- Chemokine
- CXCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 77
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASP 20 | NTc.Cm43 | PRO 189 | - | Hydrophobic |
| ASP 20 | NTc.Cm43 | PRO 189 | - | VdWContact |
| ASP 22 | NTc.Cm41 | LYS 46 | 1.32x32 | Anionic |
| ASP 22 | NTc.Cm41 | LYS 46 | 1.32x32 | HBAcceptor |
| ASP 22 | NTc.Cm41 | LYS 46 | 1.32x32 | VdWContact |
| TYR 24 | NTc.Cm39 | ASN 188 | - | Hydrophobic |
| TYR 24 | NTc.Cm39 | ASN 188 | - | VdWContact |
| TYR 24 | NTc.Cm39 | PRO 189 | - | Hydrophobic |
| TYR 24 | NTc.Cm39 | PRO 189 | - | VdWContact |
| TYR 24 | NTc.Cm39 | ASN 194 | - | VdWContact |
| ALA 25 | NTc.Cm38 | VAL 42 | 1.28x28 | Hydrophobic |
| ALA 25 | NTc.Cm38 | VAL 42 | 1.28x28 | VdWContact |
| GLU 26 | NTc.Cm37 | LYS 38 | 1.24x24 | Hydrophobic |
| LEU 27 | NTc.Cm36 | VAL 41 | 1.27x27 | Hydrophobic |
| LEU 27 | NTc.Cm36 | VAL 41 | 1.27x27 | VdWContact |
| LEU 27 | NTc.Cm36 | ASP 291 | 7.32x31 | Hydrophobic |
| LEU 27 | NTc.Cm36 | ASP 291 | 7.32x31 | VdWContact |
| LEU 27 | NTc.Cm36 | LEU 294 | 7.35x34 | Hydrophobic |
| LEU 27 | NTc.Cm36 | GLN 295 | 7.36x35 | Hydrophobic |
| LEU 27 | NTc.Cm36 | GLN 295 | 7.36x35 | VdWContact |
| ARG 28 | NTc.Cm35 | LYS 38 | 1.24x24 | HBAcceptor |
| ARG 28 | NTc.Cm35 | LYS 38 | 1.24x24 | VdWContact |
| ARG 28 | NTc.Cm35 | HIS 273 | 6.58x58 | Hydrophobic |
| ARG 28 | NTc.Cm35 | HIS 273 | 6.58x58 | VdWContact |
| ARG 28 | NTc.Cm35 | LEU 276 | 6.61x61 | Hydrophobic |
| ARG 28 | NTc.Cm35 | LEU 276 | 6.61x61 | VdWContact |
| ARG 28 | NTc.Cm35 | SER 287 | 7.28x27 | VdWContact |
| ARG 28 | NTc.Cm35 | LEU 290 | 7.31x30 | VdWContact |
| ARG 28 | NTc.Cm35 | ASP 291 | 7.32x31 | Cationic |
| ARG 28 | NTc.Cm35 | ASP 291 | 7.32x31 | HBDonor |
| ARG 28 | NTc.Cm35 | ASP 291 | 7.32x31 | VdWContact |
| MET 30 | NTc.Cm33 | LEU 35 | - | Hydrophobic |
| MET 30 | NTc.Cm33 | LEU 35 | - | VdWContact |
| MET 30 | NTc.Cm33 | CYS 36 | - | HBAcceptor |
| MET 30 | NTc.Cm33 | CYS 36 | - | VdWContact |
| ILE 32 | NTc.Cm31 | CYS 36 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | LEU 276 | 6.61x61 | Hydrophobic |
| ILE 32 | NTc.Cm31 | CYS 284 | 7.25x24 | Hydrophobic |
| ILE 32 | NTc.Cm31 | CYS 284 | 7.25x24 | VdWContact |
| LYS 33 | NTc.Cm30 | ALA 32 | - | Hydrophobic |
| LYS 33 | NTc.Cm30 | ALA 32 | - | VdWContact |
| LYS 33 | NTc.Cm30 | PHE 33 | - | Hydrophobic |
| THR 34 | NTc.Cm29 | PHE 33 | - | VdWContact |
| THR 35 | NTc.Cm28 | LEU 28 | - | Hydrophobic |
| THR 35 | NTc.Cm28 | LEU 28 | - | VdWContact |
| GLY 37 | NTc.Cm26 | TYR 24 | - | VdWContact |
| ILE 38 | NTc.Cm25 | TYR 25 | - | Hydrophobic |
| ILE 38 | NTc.Cm25 | TYR 25 | - | VdWContact |
| ILE 38 | NTc.Cm25 | LEU 28 | - | Hydrophobic |
| ILE 38 | NTc.Cm25 | LEU 28 | - | VdWContact |
| HIS 39 | NTc.Cm24 | TYR 25 | - | HBDonor |
| HIS 39 | NTc.Cm24 | TYR 25 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | TYR 25 | - | VdWContact |
| LYS 41 | NTc.Cm22 | GLU 18 | - | Cationic |
| ASN 42 | NTc.Cm21 | TYR 25 | - | Hydrophobic |
| ASN 42 | NTc.Cm21 | TYR 25 | - | VdWContact |
| LYS 51 | NTc.Cm12 | GLY 200 | - | VdWContact |
| GLY 52 | NTc.Cm11 | HIS 196 | 45.51x51 | VdWContact |
| THR 53 | NTc.Cm10 | ASN 194 | - | Hydrophobic |
| THR 53 | NTc.Cm10 | ASN 194 | - | VdWContact |
| THR 53 | NTc.Cm10 | HIS 196 | 45.51x51 | Hydrophobic |
| THR 53 | NTc.Cm10 | HIS 196 | 45.51x51 | VdWContact |
| ASN 56 | NTc.Cm7 | LYS 207 | 5.35x36 | Hydrophobic |
| ILE 61 | NTc.Cm2 | LEU 35 | - | Hydrophobic |
| ILE 61 | NTc.Cm2 | LEU 35 | - | VdWContact |
| LEU 64 | CX.4 | TYR 25 | - | Hydrophobic |
| ARG 68 | cxb1.5 | ASP 29 | - | Cationic |
| ARG 68 | cxb1.5 | ASP 29 | - | HBDonor |
| ARG 68 | cxb1.5 | ASP 29 | - | VdWContact |
| LYS 69 | cxb1.6 | MET 34 | - | VdWContact |
| LYS 69 | cxb1.6 | LEU 35 | - | HBAcceptor |
| LYS 69 | cxb1.6 | LEU 35 | - | Hydrophobic |
| LYS 69 | cxb1.6 | LEU 35 | - | VdWContact |
| ILE 70 | cxb1.8 | LEU 28 | - | Hydrophobic |
| ILE 70 | cxb1.8 | PHE 33 | - | VdWContact |
| CYS 71 | cxb1.10 | PHE 33 | - | HBDonor |
| CYS 71 | cxb1.10 | PHE 33 | - | VdWContact |
