Predicted complex interactions
CCL17_HUMAN + CXCR4
SUMMARY
- Chemokine
- CCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 65
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm32 | TRP 94 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm32 | TRP 94 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm32 | GLU 288 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm32 | GLU 288 | 7.39x38 | VdWContact |
| ALA 1 | NTc.Cm32 | PHE 292 | 7.43x42 | Hydrophobic |
| ARG 2 | NTc.Cm31 | VAL 196 | 5.35x36 | VdWContact |
| ARG 2 | NTc.Cm31 | GLN 200 | 5.39x40 | VdWContact |
| ARG 2 | NTc.Cm31 | ASP 262 | 6.58x58 | Cationic |
| ARG 2 | NTc.Cm31 | ASP 262 | 6.58x58 | HBDonor |
| ARG 2 | NTc.Cm31 | ASP 262 | 6.58x58 | VdWContact |
| ARG 2 | NTc.Cm31 | ILE 284 | 7.35x34 | Hydrophobic |
| ARG 2 | NTc.Cm31 | GLU 288 | 7.39x38 | HBDonor |
| ARG 2 | NTc.Cm31 | GLU 288 | 7.39x38 | VdWContact |
| GLY 3 | NTc.Cm30 | ASN 37 | 1.31x31 | VdWContact |
| GLY 3 | NTc.Cm30 | SER 285 | 7.36x35 | HBAcceptor |
| GLY 3 | NTc.Cm30 | SER 285 | 7.36x35 | VdWContact |
| GLY 3 | NTc.Cm30 | GLU 288 | 7.39x38 | HBDonor |
| GLY 3 | NTc.Cm30 | GLU 288 | 7.39x38 | VdWContact |
| THR 4 | NTc.Cm29 | LEU 41 | 1.35x35 | Hydrophobic |
| THR 4 | NTc.Cm29 | ASP 97 | 2.63x63 | HBDonor |
| THR 4 | NTc.Cm29 | ASP 97 | 2.63x63 | VdWContact |
| THR 4 | NTc.Cm29 | ALA 98 | 2.64x64 | Hydrophobic |
| ASN 5 | NTc.Cm28 | CYS 186 | 45.50x50 | HBDonor |
| ASN 5 | NTc.Cm28 | CYS 186 | 45.50x50 | VdWContact |
| ASN 5 | NTc.Cm28 | ASP 187 | 45.51x51 | HBDonor |
| ASN 5 | NTc.Cm28 | ASP 187 | 45.51x51 | VdWContact |
| VAL 6 | NTc.Cm27 | ARG 30 | 1.24x24 | VdWContact |
| VAL 6 | NTc.Cm27 | HIS 281 | 7.32x31 | HBAcceptor |
| VAL 6 | NTc.Cm27 | HIS 281 | 7.32x31 | Hydrophobic |
| VAL 6 | NTc.Cm27 | HIS 281 | 7.32x31 | VdWContact |
| GLY 7 | NTc.Cm26 | ARG 30 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm25 | ARG 30 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm25 | ILE 185 | - | VdWContact |
| GLU 9 | NTc.Cm24 | PRO 27 | - | Hydrophobic |
| GLU 9 | NTc.Cm24 | CYS 28 | - | VdWContact |
| GLU 9 | NTc.Cm24 | PHE 29 | - | Hydrophobic |
| GLU 9 | NTc.Cm24 | PHE 29 | - | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 28 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 28 | - | VdWContact |
| CYS 10 | NTc.Cm23 | ARG 30 | 1.24x24 | Anionic |
| CYS 11 | NTc.Cm22 | PRO 27 | - | VdWContact |
| LEU 12 | NTc.Cm21 | GLU 277 | 7.28x27 | VdWContact |
| PHE 15 | NTc.Cm18 | TYR 21 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | LYS 25 | - | Hydrophobic |
| PHE 15 | NTc.Cm18 | LYS 25 | - | VdWContact |
| PRO 20 | NTc.Cm13 | TYR 21 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | TYR 21 | - | VdWContact |
| LYS 23 | NTc.Cm10 | MET 16 | - | VdWContact |
| ASP 33 | CX.1 | PHE 189 | - | VdWContact |
| SER 35 | cxb1.1 | ASP 193 | 5.32x33 | VdWContact |
| ARG 36 | cxb1.2 | GLU 268 | 6.64x64 | Cationic |
| ARG 36 | cxb1.2 | GLU 268 | 6.64x64 | HBDonor |
| ARG 36 | cxb1.2 | GLU 268 | 6.64x64 | VdWContact |
| VAL 40 | cxb1.8 | PRO 27 | - | Hydrophobic |
| VAL 40 | cxb1.8 | PRO 27 | - | VdWContact |
| ARG 47 | B1.2 | TYR 21 | - | VdWContact |
| ALA 48 | B1.3 | GLU 26 | - | VdWContact |
| ALA 48 | B1.3 | PRO 27 | - | Hydrophobic |
| ALA 48 | B1.3 | PRO 27 | - | VdWContact |
| ALA 48 | B1.3 | PHE 29 | - | Hydrophobic |
| ALA 48 | B1.3 | PHE 29 | - | VdWContact |
| ILE 49 | B1.4 | TYR 21 | - | Hydrophobic |
| CYS 50 | B1.5 | LYS 25 | - | HBDonor |
| CYS 50 | B1.5 | LYS 25 | - | VdWContact |
| CYS 50 | B1.5 | PRO 27 | - | VdWContact |
