Predicted complex interactions
CCL19_HUMAN + CXCR4
SUMMARY
- Chemokine
- CCL19_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 88
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASP 7 | NTc.Cm22 | MET 16 | - | VdWContact |
| CYS 8 | NTc.Cm21 | MET 16 | - | Hydrophobic |
| CYS 9 | NTc.Cm20 | GLY 17 | - | VdWContact |
| LEU 10 | NTc.Cm19 | MET 16 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | GLY 17 | - | HBDonor |
| LEU 10 | NTc.Cm19 | GLY 17 | - | VdWContact |
| SER 11 | NTc.Cm18 | GLY 19 | - | HBAcceptor |
| SER 11 | NTc.Cm18 | GLY 19 | - | VdWContact |
| SER 11 | NTc.Cm18 | ASP 20 | - | VdWContact |
| VAL 12 | NTc.Cm17 | GLY 19 | - | VdWContact |
| THR 13 | NTc.Cm16 | GLY 19 | - | VdWContact |
| THR 13 | NTc.Cm16 | TYR 21 | - | VdWContact |
| LYS 15 | NTc.Cm14 | TYR 21 | - | Hydrophobic |
| LYS 15 | NTc.Cm14 | TYR 21 | - | VdWContact |
| LYS 15 | NTc.Cm14 | ASP 22 | - | Cationic |
| LYS 15 | NTc.Cm14 | ASP 22 | - | HBDonor |
| LYS 15 | NTc.Cm14 | ASP 22 | - | VdWContact |
| LYS 15 | NTc.Cm14 | SER 23 | - | HBDonor |
| LYS 15 | NTc.Cm14 | SER 23 | - | VdWContact |
| PRO 16 | NTc.Cm13 | CYS 274 | 7.25x24 | Hydrophobic |
| PRO 16 | NTc.Cm13 | CYS 274 | 7.25x24 | VdWContact |
| ILE 17 | NTc.Cm12 | GLU 26 | - | Hydrophobic |
| ILE 17 | NTc.Cm12 | GLU 26 | - | VdWContact |
| PRO 18 | NTc.Cm11 | GLU 26 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | GLU 26 | - | VdWContact |
| PRO 18 | NTc.Cm11 | PRO 27 | - | VdWContact |
| PRO 18 | NTc.Cm11 | CYS 28 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | CYS 28 | - | VdWContact |
| PRO 18 | NTc.Cm11 | PHE 29 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | PHE 29 | - | VdWContact |
| PRO 18 | NTc.Cm11 | CYS 274 | 7.25x24 | VdWContact |
| GLY 19 | NTc.Cm10 | PHE 29 | - | VdWContact |
| TYR 20 | NTc.Cm9 | PRO 27 | - | Hydrophobic |
| TYR 20 | NTc.Cm9 | PRO 27 | - | VdWContact |
| TYR 20 | NTc.Cm9 | CYS 28 | - | VdWContact |
| TYR 20 | NTc.Cm9 | ARG 30 | 1.24x24 | HBAcceptor |
| TYR 20 | NTc.Cm9 | ARG 30 | 1.24x24 | Hydrophobic |
| TYR 20 | NTc.Cm9 | ARG 30 | 1.24x24 | PiCation |
| TYR 20 | NTc.Cm9 | ARG 30 | 1.24x24 | VdWContact |
| TYR 20 | NTc.Cm9 | GLU 277 | 7.28x27 | HBDonor |
| TYR 20 | NTc.Cm9 | GLU 277 | 7.28x27 | VdWContact |
| TYR 20 | NTc.Cm9 | HIS 281 | 7.32x31 | Hydrophobic |
| TYR 20 | NTc.Cm9 | HIS 281 | 7.32x31 | VdWContact |
| ILE 21 | NTc.Cm8 | PRO 27 | - | Hydrophobic |
| ILE 21 | NTc.Cm8 | PRO 27 | - | VdWContact |
| ARG 45 | B1.4 | PRO 191 | - | VdWContact |
| ARG 45 | B1.4 | ASN 192 | - | VdWContact |
| ARG 45 | B1.4 | ASP 193 | 5.32x33 | Cationic |
| ARG 45 | B1.4 | ASP 193 | 5.32x33 | HBDonor |
| ARG 45 | B1.4 | ASP 193 | 5.32x33 | VdWContact |
| LEU 49 | b1b2.4 | GLU 26 | - | Hydrophobic |
| LEU 49 | b1b2.4 | GLU 26 | - | VdWContact |
| CYS 50 | b1b2.6 | GLY 17 | - | VdWContact |
| CYS 50 | b1b2.6 | SER 18 | - | VdWContact |
| CYS 50 | b1b2.6 | GLY 19 | - | VdWContact |
| ARG 60 | B2.2 | PHE 29 | - | Hydrophobic |
| ARG 60 | B2.2 | PHE 29 | - | VdWContact |
| ILE 61 | B2.3 | PHE 29 | - | Hydrophobic |
| ILE 61 | B2.3 | PHE 29 | - | VdWContact |
| ARG 64 | B2.6 | PHE 29 | - | CationPi |
| ARG 64 | B2.6 | PHE 29 | - | Hydrophobic |
| ARG 64 | B2.6 | PHE 29 | - | VdWContact |
| ARG 64 | B2.6 | ARG 30 | 1.24x24 | HBDonor |
| ARG 64 | B2.6 | ARG 30 | 1.24x24 | VdWContact |
| ARG 67 | b2b3.11 | GLU 31 | 1.25x25 | Cationic |
| ARG 67 | b2b3.11 | GLU 31 | 1.25x25 | HBDonor |
| ARG 67 | b2b3.11 | GLU 31 | 1.25x25 | VdWContact |
| THR 68 | b2b3.12 | ASP 181 | - | Hydrophobic |
| THR 68 | b2b3.12 | ASP 181 | - | VdWContact |
| THR 68 | b2b3.12 | ARG 183 | - | Hydrophobic |
| SER 69 | B3.1 | ASP 181 | - | HBDonor |
| SER 69 | B3.1 | ASP 181 | - | VdWContact |
| LYS 71 | B3.3 | ASP 181 | - | VdWContact |
| LYS 71 | B3.3 | ASP 182 | - | Hydrophobic |
| LYS 71 | B3.3 | ASP 182 | - | VdWContact |
| MET 72 | B3.4 | GLU 179 | - | Hydrophobic |
| MET 72 | B3.4 | GLU 179 | - | VdWContact |
| MET 72 | B3.4 | ASP 181 | - | VdWContact |
| MET 72 | B3.4 | ASP 182 | - | VdWContact |
| ARG 74 | b3h.2 | ASP 182 | - | HBDonor |
| ARG 74 | b3h.2 | ASP 182 | - | VdWContact |
| ARG 75 | b3h.3 | ASN 101 | 23.49x49 | VdWContact |
| ARG 75 | b3h.3 | TYR 103 | 23.51x51 | VdWContact |
| ARG 75 | b3h.3 | ASP 182 | - | HBDonor |
| ARG 75 | b3h.3 | ASP 182 | - | Hydrophobic |
| ARG 75 | b3h.3 | ASP 182 | - | VdWContact |
| SER 76 | b3h.4 | ASP 182 | - | HBDonor |
| SER 76 | b3h.4 | ASP 182 | - | VdWContact |
