Predicted complex interactions
CCL20_HUMAN + CXCR4
SUMMARY
- Chemokine
- CCL20_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 66
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 2 | NTc.Cm30 | ARG 30 | 1.24x24 | HBAcceptor |
| SER 2 | NTc.Cm30 | ARG 30 | 1.24x24 | VdWContact |
| ASN 3 | NTc.Cm29 | ARG 30 | 1.24x24 | VdWContact |
| ASN 3 | NTc.Cm29 | ALA 34 | 1.28x28 | Hydrophobic |
| ASN 3 | NTc.Cm29 | ALA 34 | 1.28x28 | VdWContact |
| ASN 3 | NTc.Cm29 | ASN 37 | 1.31x31 | HBAcceptor |
| ASN 3 | NTc.Cm29 | ASN 37 | 1.31x31 | VdWContact |
| PHE 4 | NTc.Cm28 | ARG 30 | 1.24x24 | VdWContact |
| PHE 4 | NTc.Cm28 | ALA 180 | - | Hydrophobic |
| PHE 4 | NTc.Cm28 | ALA 180 | - | VdWContact |
| PHE 4 | NTc.Cm28 | ILE 185 | - | Hydrophobic |
| PHE 4 | NTc.Cm28 | ILE 185 | - | VdWContact |
| ASP 5 | NTc.Cm27 | CYS 28 | - | VdWContact |
| ASP 5 | NTc.Cm27 | PHE 29 | - | Hydrophobic |
| ASP 5 | NTc.Cm27 | PHE 29 | - | VdWContact |
| ASP 5 | NTc.Cm27 | ARG 30 | 1.24x24 | HBAcceptor |
| ASP 5 | NTc.Cm27 | ARG 30 | 1.24x24 | VdWContact |
| CYS 6 | NTc.Cm26 | CYS 28 | - | HBAcceptor |
| CYS 6 | NTc.Cm26 | CYS 28 | - | HBDonor |
| CYS 6 | NTc.Cm26 | CYS 28 | - | VdWContact |
| CYS 6 | NTc.Cm26 | ARG 30 | 1.24x24 | Anionic |
| LEU 8 | NTc.Cm24 | CYS 28 | - | Hydrophobic |
| LEU 8 | NTc.Cm24 | CYS 28 | - | VdWContact |
| LEU 8 | NTc.Cm24 | GLU 277 | 7.28x27 | Hydrophobic |
| LEU 8 | NTc.Cm24 | GLU 277 | 7.28x27 | VdWContact |
| GLY 9 | NTc.Cm23 | LYS 25 | - | VdWContact |
| THR 11 | NTc.Cm21 | SER 23 | - | HBDonor |
| THR 11 | NTc.Cm21 | SER 23 | - | VdWContact |
| ARG 13 | NTc.Cm19 | ASP 20 | - | Cationic |
| ARG 13 | NTc.Cm19 | ASP 20 | - | HBDonor |
| ARG 13 | NTc.Cm19 | ASP 20 | - | VdWContact |
| ARG 13 | NTc.Cm19 | SER 23 | - | VdWContact |
| ILE 14 | NTc.Cm18 | TYR 12 | - | Hydrophobic |
| LEU 15 | NTc.Cm17 | MET 16 | - | Hydrophobic |
| LEU 15 | NTc.Cm17 | MET 24 | - | Hydrophobic |
| LEU 15 | NTc.Cm17 | MET 24 | - | VdWContact |
| HIS 16 | NTc.Cm16 | TYR 12 | - | Hydrophobic |
| HIS 16 | NTc.Cm16 | TYR 12 | - | PiStacking |
| HIS 16 | NTc.Cm16 | TYR 12 | - | VdWContact |
| PHE 19 | NTc.Cm13 | MET 16 | - | Hydrophobic |
| PHE 19 | NTc.Cm13 | MET 16 | - | VdWContact |
| ASN 29 | NTc.Cm3 | PHE 189 | - | Hydrophobic |
| ASN 29 | NTc.Cm3 | PHE 189 | - | VdWContact |
| GLU 30 | NTc.Cm2 | SER 178 | - | VdWContact |
| ASP 33 | CX.5 | ARG 30 | 1.24x24 | Anionic |
| ASP 33 | CX.5 | ARG 30 | 1.24x24 | VdWContact |
| ASP 33 | CX.5 | ASP 193 | 5.32x33 | VdWContact |
| ASP 33 | CX.5 | LEU 266 | 6.62x62 | Hydrophobic |
| ASP 33 | CX.5 | LEU 266 | 6.62x62 | VdWContact |
| ILE 34 | cxb1.1 | ASP 193 | 5.32x33 | VdWContact |
| ILE 38 | cxb1.7 | PRO 27 | - | Hydrophobic |
| LYS 43 | cxb1.15 | TYR 21 | - | HBDonor |
| LYS 43 | cxb1.15 | TYR 21 | - | Hydrophobic |
| LYS 43 | cxb1.15 | TYR 21 | - | VdWContact |
| LEU 45 | B1.1 | TYR 21 | - | Hydrophobic |
| LEU 45 | B1.1 | TYR 21 | - | VdWContact |
| LEU 45 | B1.1 | GLU 26 | - | VdWContact |
| SER 46 | B1.2 | GLU 26 | - | VdWContact |
| SER 46 | B1.2 | PRO 27 | - | VdWContact |
| VAL 47 | B1.3 | MET 24 | - | Hydrophobic |
| CYS 48 | B1.4 | LYS 25 | - | HBDonor |
| CYS 48 | B1.4 | LYS 25 | - | Hydrophobic |
| CYS 48 | B1.4 | LYS 25 | - | VdWContact |
| CYS 48 | B1.4 | GLU 26 | - | VdWContact |
| CYS 48 | B1.4 | PRO 27 | - | VdWContact |
| THR 54 | b1b2.7 | TYR 7 | - | HBDonor |
