Predicted complex interactions
CCL21_HUMAN + CXCR4
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 79
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 6 | NTc.Cm25 | GLU 26 | - | VdWContact |
| ASP 7 | NTc.Cm24 | GLU 26 | - | Hydrophobic |
| ASP 7 | NTc.Cm24 | GLU 26 | - | VdWContact |
| ASP 7 | NTc.Cm24 | PRO 27 | - | VdWContact |
| CYS 8 | NTc.Cm23 | PRO 27 | - | VdWContact |
| ARG 15 | NTc.Cm16 | ASP 181 | - | Cationic |
| ARG 15 | NTc.Cm16 | ASP 181 | - | HBDonor |
| ARG 15 | NTc.Cm16 | ASP 181 | - | VdWContact |
| ARG 15 | NTc.Cm16 | ASP 182 | - | Cationic |
| ARG 15 | NTc.Cm16 | ASP 182 | - | HBDonor |
| ARG 15 | NTc.Cm16 | ASP 182 | - | VdWContact |
| ILE 17 | NTc.Cm14 | ALA 180 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | ALA 180 | - | VdWContact |
| PRO 18 | NTc.Cm13 | GLU 179 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | GLU 179 | - | VdWContact |
| VAL 21 | NTc.Cm10 | SER 178 | - | VdWContact |
| VAL 21 | NTc.Cm10 | GLU 179 | - | VdWContact |
| VAL 21 | NTc.Cm10 | ALA 180 | - | Hydrophobic |
| VAL 21 | NTc.Cm10 | ALA 180 | - | VdWContact |
| VAL 21 | NTc.Cm10 | ILE 185 | - | Hydrophobic |
| VAL 21 | NTc.Cm10 | PHE 189 | - | Hydrophobic |
| ARG 23 | NTc.Cm8 | ASP 193 | 5.32x33 | Cationic |
| ARG 23 | NTc.Cm8 | ASP 193 | 5.32x33 | HBDonor |
| ARG 23 | NTc.Cm8 | ASP 193 | 5.32x33 | VdWContact |
| ARG 26 | NTc.Cm5 | LYS 25 | - | HBDonor |
| ARG 26 | NTc.Cm5 | LYS 25 | - | VdWContact |
| LEU 40 | cxb1.11 | PRO 27 | - | Hydrophobic |
| LEU 40 | cxb1.11 | PRO 27 | - | VdWContact |
| ARG 44 | B1.1 | PHE 189 | - | Hydrophobic |
| LYS 45 | B1.2 | ASP 97 | 2.63x63 | Cationic |
| LYS 45 | B1.2 | ASP 97 | 2.63x63 | HBDonor |
| LYS 45 | B1.2 | ILE 185 | - | Hydrophobic |
| LYS 45 | B1.2 | CYS 186 | 45.50x50 | HBDonor |
| LYS 45 | B1.2 | CYS 186 | 45.50x50 | VdWContact |
| LYS 45 | B1.2 | ASP 187 | 45.51x51 | Cationic |
| LYS 45 | B1.2 | ASP 187 | 45.51x51 | Hydrophobic |
| LYS 45 | B1.2 | ASP 187 | 45.51x51 | VdWContact |
| ARG 46 | B1.3 | ARG 30 | 1.24x24 | HBAcceptor |
| ARG 46 | B1.3 | ARG 30 | 1.24x24 | VdWContact |
| ARG 46 | B1.3 | ASP 262 | 6.58x58 | Cationic |
| ARG 46 | B1.3 | LEU 266 | 6.62x62 | VdWContact |
| ARG 46 | B1.3 | GLU 277 | 7.28x27 | Cationic |
| ARG 46 | B1.3 | HIS 281 | 7.32x31 | Hydrophobic |
| ARG 46 | B1.3 | HIS 281 | 7.32x31 | VdWContact |
| GLN 48 | B1.5 | ARG 30 | 1.24x24 | VdWContact |
| GLN 48 | B1.5 | ALA 180 | - | VdWContact |
| GLN 48 | B1.5 | ILE 185 | - | VdWContact |
| ALA 49 | B1.6 | PHE 29 | - | VdWContact |
| GLU 50 | B1.7 | PRO 27 | - | Hydrophobic |
| GLU 50 | B1.7 | PRO 27 | - | VdWContact |
| GLU 50 | B1.7 | CYS 28 | - | HBDonor |
| GLU 50 | B1.7 | CYS 28 | - | Hydrophobic |
| GLU 50 | B1.7 | CYS 28 | - | VdWContact |
| CYS 52 | b1b2.6 | PHE 29 | - | VdWContact |
| LYS 75 | B3.3 | ASP 22 | - | Cationic |
| LYS 75 | B3.3 | ASP 22 | - | Hydrophobic |
| LYS 75 | B3.3 | ASP 22 | - | VdWContact |
| LYS 75 | B3.3 | SER 23 | - | HBDonor |
| LYS 75 | B3.3 | SER 23 | - | VdWContact |
| GLN 78 | b3h.2 | ASP 20 | - | VdWContact |
| ARG 81 | H.1 | GLU 14 | - | VdWContact |
| ASP 83 | H.3 | GLU 14 | - | VdWContact |
| ARG 84 | H.4 | TYR 12 | - | Hydrophobic |
| ARG 84 | H.4 | TYR 12 | - | VdWContact |
| ARG 84 | H.4 | GLU 14 | - | Cationic |
| ARG 84 | H.4 | GLU 14 | - | Hydrophobic |
| ARG 84 | H.4 | GLU 14 | - | VdWContact |
| GLY 85 | H.5 | TYR 12 | - | VdWContact |
| ALA 86 | H.6 | ASP 10 | - | HBDonor |
| ALA 86 | H.6 | ASP 10 | - | VdWContact |
| ALA 86 | H.6 | ASN 11 | - | VdWContact |
| ALA 86 | H.6 | TYR 12 | - | VdWContact |
| SER 87 | H.7 | ASP 10 | - | VdWContact |
| SER 87 | H.7 | TYR 12 | - | VdWContact |
| LYS 88 | H.8 | THR 8 | - | VdWContact |
| LYS 88 | H.8 | ASP 10 | - | Cationic |
| LYS 88 | H.8 | ASP 10 | - | HBDonor |
| LYS 88 | H.8 | ASP 10 | - | Hydrophobic |
| LYS 88 | H.8 | ASP 10 | - | VdWContact |
