Predicted complex interactions
CCL23_HUMAN + CXCR4
SUMMARY
- Chemokine
- CCL23_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 71
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 29 | NTc.Cm42 | GLU 31 | 1.25x25 | Hydrophobic |
| THR 29 | NTc.Cm42 | GLU 31 | 1.25x25 | VdWContact |
| SER 30 | NTc.Cm41 | ASP 181 | - | HBDonor |
| SER 30 | NTc.Cm41 | ASP 181 | - | VdWContact |
| ALA 31 | NTc.Cm40 | ARG 30 | 1.24x24 | Hydrophobic |
| ALA 31 | NTc.Cm40 | ARG 30 | 1.24x24 | VdWContact |
| ASP 32 | NTc.Cm39 | CYS 28 | - | VdWContact |
| ASP 32 | NTc.Cm39 | PHE 29 | - | VdWContact |
| ASP 32 | NTc.Cm39 | ARG 30 | 1.24x24 | HBAcceptor |
| ASP 32 | NTc.Cm39 | ARG 30 | 1.24x24 | VdWContact |
| ILE 35 | NTc.Cm36 | ARG 30 | 1.24x24 | VdWContact |
| ILE 35 | NTc.Cm36 | LEU 266 | 6.62x62 | Hydrophobic |
| SER 36 | NTc.Cm35 | LYS 25 | - | HBAcceptor |
| SER 36 | NTc.Cm35 | LYS 25 | - | VdWContact |
| THR 38 | NTc.Cm33 | SER 23 | - | VdWContact |
| THR 38 | NTc.Cm33 | MET 24 | - | VdWContact |
| THR 38 | NTc.Cm33 | LYS 25 | - | HBAcceptor |
| THR 38 | NTc.Cm33 | LYS 25 | - | VdWContact |
| ARG 40 | NTc.Cm31 | ASP 20 | - | Cationic |
| ARG 40 | NTc.Cm31 | ASP 20 | - | HBDonor |
| ARG 40 | NTc.Cm31 | ASP 20 | - | VdWContact |
| ARG 40 | NTc.Cm31 | SER 23 | - | VdWContact |
| ILE 42 | NTc.Cm29 | MET 24 | - | Hydrophobic |
| ILE 42 | NTc.Cm29 | MET 24 | - | VdWContact |
| PRO 43 | NTc.Cm28 | MET 16 | - | Hydrophobic |
| LEU 46 | NTc.Cm25 | MET 16 | - | Hydrophobic |
| LEU 46 | NTc.Cm25 | MET 16 | - | VdWContact |
| LEU 46 | NTc.Cm25 | TYR 21 | - | Hydrophobic |
| LEU 46 | NTc.Cm25 | TYR 21 | - | VdWContact |
| ASN 54 | NTc.Cm17 | ALA 180 | - | VdWContact |
| SER 55 | NTc.Cm16 | GLU 179 | - | HBDonor |
| SER 55 | NTc.Cm16 | GLU 179 | - | VdWContact |
| GLU 56 | NTc.Cm15 | SER 178 | - | VdWContact |
| GLU 56 | NTc.Cm15 | ALA 180 | - | Hydrophobic |
| GLU 56 | NTc.Cm15 | ALA 180 | - | VdWContact |
| GLU 56 | NTc.Cm15 | ILE 185 | - | HBAcceptor |
| GLU 56 | NTc.Cm15 | ILE 185 | - | Hydrophobic |
| GLU 56 | NTc.Cm15 | ILE 185 | - | VdWContact |
| GLU 56 | NTc.Cm15 | PHE 189 | - | Hydrophobic |
| GLU 56 | NTc.Cm15 | PHE 189 | - | VdWContact |
| SER 58 | NTc.Cm13 | ASP 193 | 5.32x33 | HBDonor |
| SER 58 | NTc.Cm13 | ASP 193 | 5.32x33 | VdWContact |
| LYS 59 | NTc.Cm12 | ASP 193 | 5.32x33 | Cationic |
| LYS 59 | NTc.Cm12 | ASP 193 | 5.32x33 | HBDonor |
| LYS 59 | NTc.Cm12 | ASP 193 | 5.32x33 | VdWContact |
| ILE 63 | NTc.Cm8 | PRO 27 | - | Hydrophobic |
| ILE 63 | NTc.Cm8 | PRO 27 | - | VdWContact |
| THR 66 | NTc.Cm5 | TYR 21 | - | Hydrophobic |
| THR 66 | NTc.Cm5 | MET 24 | - | Hydrophobic |
| THR 66 | NTc.Cm5 | MET 24 | - | VdWContact |
| LYS 68 | NTc.Cm3 | TYR 21 | - | Hydrophobic |
| LYS 68 | NTc.Cm3 | TYR 21 | - | VdWContact |
| ARG 70 | NTc.Cm1 | TYR 21 | - | HBDonor |
| ARG 70 | NTc.Cm1 | TYR 21 | - | VdWContact |
| ARG 70 | NTc.Cm1 | ASP 22 | - | Cationic |
| ARG 70 | NTc.Cm1 | ASP 22 | - | HBDonor |
| ARG 70 | NTc.Cm1 | ASP 22 | - | VdWContact |
| ARG 70 | NTc.Cm1 | GLU 26 | - | Cationic |
| ARG 70 | NTc.Cm1 | GLU 26 | - | VdWContact |
| ARG 71 | CX.1 | GLU 26 | - | VdWContact |
| ARG 71 | CX.1 | PRO 27 | - | Hydrophobic |
| ARG 71 | CX.1 | PRO 27 | - | VdWContact |
| ARG 71 | CX.1 | PHE 29 | - | Hydrophobic |
| ARG 71 | CX.1 | PHE 29 | - | VdWContact |
| PHE 72 | CX.5 | MET 24 | - | Hydrophobic |
| PHE 72 | CX.5 | MET 24 | - | VdWContact |
| PHE 72 | CX.5 | LYS 25 | - | VdWContact |
| PHE 72 | CX.5 | GLU 26 | - | VdWContact |
| PHE 72 | CX.5 | PRO 27 | - | VdWContact |
| CYS 73 | cxb1.1 | LYS 25 | - | HBDonor |
| CYS 73 | cxb1.1 | LYS 25 | - | VdWContact |
