Predicted complex interactions
CCL24_HUMAN + CXCR4
SUMMARY
- Chemokine
- CCL24_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 141
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm32 | ALA 34 | 1.28x28 | Hydrophobic |
| VAL 1 | NTc.Cm32 | LYS 38 | 1.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm32 | LYS 38 | 1.32x32 | VdWContact |
| VAL 1 | NTc.Cm32 | ALA 98 | 2.64x64 | Hydrophobic |
| VAL 1 | NTc.Cm32 | ALA 98 | 2.64x64 | VdWContact |
| VAL 2 | NTc.Cm31 | ALA 34 | 1.28x28 | VdWContact |
| ILE 3 | NTc.Cm30 | ASP 181 | - | Hydrophobic |
| ILE 3 | NTc.Cm30 | ASP 181 | - | VdWContact |
| ILE 3 | NTc.Cm30 | ARG 183 | - | VdWContact |
| PRO 4 | NTc.Cm29 | ARG 30 | 1.24x24 | VdWContact |
| PRO 4 | NTc.Cm29 | GLU 31 | 1.25x25 | Hydrophobic |
| PRO 4 | NTc.Cm29 | GLU 31 | 1.25x25 | VdWContact |
| PRO 4 | NTc.Cm29 | ALA 34 | 1.28x28 | Hydrophobic |
| PRO 4 | NTc.Cm29 | ALA 34 | 1.28x28 | VdWContact |
| SER 5 | NTc.Cm28 | ASP 181 | - | VdWContact |
| PRO 6 | NTc.Cm27 | PRO 27 | - | Hydrophobic |
| PRO 6 | NTc.Cm27 | PRO 27 | - | VdWContact |
| PRO 6 | NTc.Cm27 | PHE 29 | - | Hydrophobic |
| CYS 7 | NTc.Cm26 | CYS 28 | - | HBAcceptor |
| CYS 7 | NTc.Cm26 | CYS 28 | - | HBDonor |
| CYS 7 | NTc.Cm26 | CYS 28 | - | Hydrophobic |
| CYS 7 | NTc.Cm26 | CYS 28 | - | VdWContact |
| MET 9 | NTc.Cm24 | CYS 28 | - | Hydrophobic |
| MET 9 | NTc.Cm24 | CYS 28 | - | VdWContact |
| MET 9 | NTc.Cm24 | ARG 30 | 1.24x24 | VdWContact |
| MET 9 | NTc.Cm24 | CYS 274 | 7.25x24 | Hydrophobic |
| MET 9 | NTc.Cm24 | CYS 274 | 7.25x24 | VdWContact |
| MET 9 | NTc.Cm24 | GLU 277 | 7.28x27 | Hydrophobic |
| MET 9 | NTc.Cm24 | GLU 277 | 7.28x27 | VdWContact |
| PHE 10 | NTc.Cm23 | LYS 25 | - | Hydrophobic |
| PHE 10 | NTc.Cm23 | LYS 25 | - | PiCation |
| PHE 10 | NTc.Cm23 | LYS 25 | - | VdWContact |
| VAL 12 | NTc.Cm21 | MET 24 | - | Hydrophobic |
| LYS 14 | NTc.Cm19 | ASP 20 | - | Cationic |
| LYS 14 | NTc.Cm19 | ASP 20 | - | HBDonor |
| LYS 14 | NTc.Cm19 | ASP 20 | - | VdWContact |
| LYS 14 | NTc.Cm19 | MET 24 | - | Hydrophobic |
| ILE 16 | NTc.Cm17 | TYR 21 | - | Hydrophobic |
| ILE 16 | NTc.Cm17 | MET 24 | - | Hydrophobic |
| ILE 16 | NTc.Cm17 | MET 24 | - | VdWContact |
| PRO 17 | NTc.Cm16 | MET 16 | - | Hydrophobic |
| PRO 17 | NTc.Cm16 | TYR 21 | - | VdWContact |
| ARG 20 | NTc.Cm13 | MET 16 | - | HBDonor |
| ARG 20 | NTc.Cm13 | MET 16 | - | VdWContact |
| ARG 20 | NTc.Cm13 | TYR 21 | - | CationPi |
| ARG 29 | NTc.Cm4 | TYR 190 | - | VdWContact |
| ARG 29 | NTc.Cm4 | ASN 192 | - | HBDonor |
| ARG 29 | NTc.Cm4 | ASN 192 | - | VdWContact |
| ARG 29 | NTc.Cm4 | ASP 193 | 5.32x33 | Cationic |
| ARG 29 | NTc.Cm4 | ASP 193 | 5.32x33 | HBDonor |
| ARG 29 | NTc.Cm4 | ASP 193 | 5.32x33 | VdWContact |
| ARG 29 | NTc.Cm4 | VAL 196 | 5.35x36 | VdWContact |
| LEU 33 | CX.1 | ILE 265 | 6.61x61 | Hydrophobic |
| LEU 33 | CX.1 | ILE 265 | 6.61x61 | VdWContact |
| LEU 33 | CX.1 | LEU 266 | 6.62x62 | Hydrophobic |
| LEU 33 | CX.1 | LEU 266 | 6.62x62 | VdWContact |
| LYS 34 | CX.5 | ASP 193 | 5.32x33 | VdWContact |
| LYS 34 | CX.5 | GLU 268 | 6.64x64 | Cationic |
| LYS 34 | CX.5 | GLU 268 | 6.64x64 | HBDonor |
| LYS 34 | CX.5 | GLU 268 | 6.64x64 | VdWContact |
| ILE 38 | cxb1.6 | PRO 27 | - | Hydrophobic |
| ILE 38 | cxb1.6 | PRO 27 | - | VdWContact |
| GLN 46 | B1.1 | PRO 27 | - | Hydrophobic |
| GLN 46 | B1.1 | PRO 27 | - | VdWContact |
| PHE 47 | B1.2 | MET 24 | - | Hydrophobic |
| PHE 47 | B1.2 | PRO 27 | - | VdWContact |
| CYS 48 | B1.3 | PRO 27 | - | VdWContact |
| LYS 52 | B1.7 | ASN 192 | - | VdWContact |
| LYS 52 | B1.7 | ASP 193 | 5.32x33 | Cationic |
| LYS 52 | B1.7 | ASP 193 | 5.32x33 | HBDonor |
| LYS 52 | B1.7 | ASP 193 | 5.32x33 | VdWContact |
| ALA 78 | b3h.3 | ASP 182 | - | Hydrophobic |
| ALA 78 | b3h.3 | ASP 182 | - | VdWContact |
| VAL 79 | b3h.4 | ASP 181 | - | VdWContact |
| VAL 79 | b3h.4 | ASP 182 | - | HBDonor |
| VAL 79 | b3h.4 | ASP 182 | - | VdWContact |
| LYS 80 | H.1 | ASP 182 | - | Hydrophobic |
| LYS 80 | H.1 | ASP 182 | - | VdWContact |
| GLY 81 | H.2 | ARG 183 | - | HBAcceptor |
| GLY 81 | H.2 | ARG 183 | - | VdWContact |
| PRO 82 | H.3 | ALA 100 | 2.66x66 | VdWContact |
| PRO 82 | H.3 | ARG 183 | - | HBAcceptor |
| PRO 82 | H.3 | ARG 183 | - | VdWContact |
| VAL 83 | H.4 | ASN 101 | 23.49x49 | VdWContact |
| VAL 83 | H.4 | ARG 183 | - | Hydrophobic |
| VAL 83 | H.4 | ARG 183 | - | VdWContact |
| VAL 83 | H.4 | ILE 185 | - | Hydrophobic |
| VAL 83 | H.4 | ILE 185 | - | VdWContact |
| GLN 84 | H.5 | VAL 96 | 2.62x62 | HBDonor |
| GLN 84 | H.5 | VAL 96 | 2.62x62 | VdWContact |
| GLN 84 | H.5 | ASP 97 | 2.63x63 | VdWContact |
| GLN 84 | H.5 | ALA 98 | 2.64x64 | VdWContact |
| GLN 84 | H.5 | VAL 99 | 2.65x65 | HBDonor |
| GLN 84 | H.5 | VAL 99 | 2.65x65 | VdWContact |
| GLN 84 | H.5 | ALA 100 | 2.66x66 | VdWContact |
| GLN 84 | H.5 | ASN 101 | 23.49x49 | VdWContact |
| ARG 85 | H.6 | ASP 97 | 2.63x63 | HBDonor |
| ARG 85 | H.6 | ASP 97 | 2.63x63 | VdWContact |
| ARG 85 | H.6 | ILE 185 | - | HBDonor |
| ARG 85 | H.6 | ILE 185 | - | Hydrophobic |
| ARG 85 | H.6 | ILE 185 | - | VdWContact |
| ARG 85 | H.6 | CYS 186 | 45.50x50 | VdWContact |
| ARG 85 | H.6 | ASP 187 | 45.51x51 | Cationic |
| ARG 85 | H.6 | ASP 187 | 45.51x51 | HBDonor |
| ARG 85 | H.6 | ASP 187 | 45.51x51 | VdWContact |
| ARG 85 | H.6 | PHE 189 | - | VdWContact |
| TYR 86 | H.7 | ASN 37 | 1.31x31 | VdWContact |
| TYR 86 | H.7 | LEU 41 | 1.35x35 | Hydrophobic |
| TYR 86 | H.7 | LEU 41 | 1.35x35 | VdWContact |
| TYR 86 | H.7 | PRO 42 | 1.36x36 | Hydrophobic |
| TYR 86 | H.7 | PRO 42 | 1.36x36 | VdWContact |
| TYR 86 | H.7 | TYR 45 | 1.39x39 | Hydrophobic |
| TYR 86 | H.7 | TYR 45 | 1.39x39 | VdWContact |
| TYR 86 | H.7 | TRP 94 | 2.60x60 | Hydrophobic |
| TYR 86 | H.7 | TRP 94 | 2.60x60 | VdWContact |
| TYR 86 | H.7 | ALA 95 | 2.61x61 | VdWContact |
| TYR 86 | H.7 | ALA 98 | 2.64x64 | Hydrophobic |
| TYR 86 | H.7 | ALA 98 | 2.64x64 | VdWContact |
| PRO 87 | H.8 | TYR 45 | 1.39x39 | Hydrophobic |
| PRO 87 | H.8 | TYR 45 | 1.39x39 | VdWContact |
| PRO 87 | H.8 | TRP 94 | 2.60x60 | Hydrophobic |
| PRO 87 | H.8 | TRP 94 | 2.60x60 | VdWContact |
| PRO 87 | H.8 | PHE 292 | 7.43x42 | Hydrophobic |
| GLY 88 | H.9 | GLU 288 | 7.39x38 | VdWContact |
| ASN 89 | H.10 | TYR 255 | 6.51x51 | Hydrophobic |
| ASN 89 | H.10 | TYR 255 | 6.51x51 | VdWContact |
| ASN 89 | H.10 | ILE 259 | 6.55x55 | Hydrophobic |
| ASN 89 | H.10 | ILE 259 | 6.55x55 | VdWContact |
| ASN 89 | H.10 | ILE 284 | 7.35x34 | Hydrophobic |
| ASN 89 | H.10 | ILE 284 | 7.35x34 | VdWContact |
| ASN 89 | H.10 | GLU 288 | 7.39x38 | HBDonor |
| ASN 89 | H.10 | GLU 288 | 7.39x38 | VdWContact |
| GLN 90 | CT.1 | ASP 187 | 45.51x51 | VdWContact |
| THR 91 | CT.2 | ILE 259 | 6.55x55 | Hydrophobic |
| THR 91 | CT.2 | ASP 262 | 6.58x58 | Hydrophobic |
| THR 91 | CT.2 | ASP 262 | 6.58x58 | VdWContact |
| THR 91 | CT.2 | HIS 281 | 7.32x31 | VdWContact |
| THR 91 | CT.2 | ILE 284 | 7.35x34 | Hydrophobic |
| THR 91 | CT.2 | ILE 284 | 7.35x34 | VdWContact |
| THR 92 | CT.3 | VAL 196 | 5.35x36 | Hydrophobic |
| THR 92 | CT.3 | HIS 281 | 7.32x31 | VdWContact |
