Predicted complex interactions
CCL26_HUMAN + CXCR4
SUMMARY
- Chemokine
- CCL26_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 82
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 1 | NTc.Cm32 | TRP 94 | 2.60x60 | Hydrophobic |
| THR 1 | NTc.Cm32 | HIS 113 | 3.29x29 | Hydrophobic |
| THR 1 | NTc.Cm32 | TYR 116 | 3.32x32 | Hydrophobic |
| THR 1 | NTc.Cm32 | ASP 187 | 45.51x51 | HBDonor |
| THR 1 | NTc.Cm32 | ASP 187 | 45.51x51 | VdWContact |
| THR 1 | NTc.Cm32 | ARG 188 | 45.52x52 | VdWContact |
| THR 1 | NTc.Cm32 | GLU 288 | 7.39x38 | Cationic |
| THR 1 | NTc.Cm32 | GLU 288 | 7.39x38 | HBDonor |
| THR 1 | NTc.Cm32 | GLU 288 | 7.39x38 | VdWContact |
| ARG 2 | NTc.Cm31 | VAL 196 | 5.35x36 | VdWContact |
| ARG 2 | NTc.Cm31 | ASP 262 | 6.58x58 | Cationic |
| ARG 2 | NTc.Cm31 | ASP 262 | 6.58x58 | HBDonor |
| ARG 2 | NTc.Cm31 | ASP 262 | 6.58x58 | VdWContact |
| ARG 2 | NTc.Cm31 | LEU 266 | 6.62x62 | VdWContact |
| ARG 2 | NTc.Cm31 | HIS 281 | 7.32x31 | VdWContact |
| GLY 3 | NTc.Cm30 | ASN 37 | 1.31x31 | HBAcceptor |
| GLY 3 | NTc.Cm30 | ASN 37 | 1.31x31 | VdWContact |
| ASP 5 | NTc.Cm28 | ARG 30 | 1.24x24 | Anionic |
| ASP 5 | NTc.Cm28 | ARG 30 | 1.24x24 | HBAcceptor |
| ASP 5 | NTc.Cm28 | ARG 30 | 1.24x24 | Hydrophobic |
| ASP 5 | NTc.Cm28 | ARG 30 | 1.24x24 | VdWContact |
| ASP 5 | NTc.Cm28 | ASN 33 | 1.27x27 | HBAcceptor |
| ASP 5 | NTc.Cm28 | ASN 33 | 1.27x27 | Hydrophobic |
| ASP 5 | NTc.Cm28 | ASN 33 | 1.27x27 | VdWContact |
| ASP 5 | NTc.Cm28 | ALA 34 | 1.28x28 | VdWContact |
| ASP 5 | NTc.Cm28 | HIS 281 | 7.32x31 | VdWContact |
| ILE 6 | NTc.Cm27 | ARG 30 | 1.24x24 | VdWContact |
| ILE 6 | NTc.Cm27 | ALA 180 | - | Hydrophobic |
| ILE 6 | NTc.Cm27 | ILE 185 | - | Hydrophobic |
| ILE 6 | NTc.Cm27 | ILE 185 | - | VdWContact |
| SER 7 | NTc.Cm26 | GLU 31 | 1.25x25 | VdWContact |
| THR 9 | NTc.Cm24 | PRO 27 | - | Hydrophobic |
| THR 9 | NTc.Cm24 | PRO 27 | - | VdWContact |
| THR 9 | NTc.Cm24 | CYS 28 | - | VdWContact |
| THR 9 | NTc.Cm24 | PHE 29 | - | Hydrophobic |
| CYS 10 | NTc.Cm23 | CYS 28 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 28 | - | HBDonor |
| CYS 10 | NTc.Cm23 | CYS 28 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 28 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | ARG 30 | 1.24x24 | VdWContact |
| PHE 12 | NTc.Cm21 | GLU 277 | 7.28x27 | VdWContact |
| GLN 13 | NTc.Cm20 | LYS 25 | - | HBAcceptor |
| GLN 13 | NTc.Cm20 | LYS 25 | - | Hydrophobic |
| GLN 13 | NTc.Cm20 | LYS 25 | - | VdWContact |
| SER 15 | NTc.Cm18 | SER 23 | - | VdWContact |
| LYS 17 | NTc.Cm16 | ASP 20 | - | Cationic |
| LYS 17 | NTc.Cm16 | ASP 20 | - | HBDonor |
| LYS 17 | NTc.Cm16 | ASP 20 | - | VdWContact |
| LEU 19 | NTc.Cm14 | MET 24 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | MET 16 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | MET 16 | - | VdWContact |
| TRP 23 | NTc.Cm10 | MET 16 | - | Hydrophobic |
| TRP 23 | NTc.Cm10 | MET 16 | - | VdWContact |
| TRP 23 | NTc.Cm10 | TYR 21 | - | Hydrophobic |
| TRP 23 | NTc.Cm10 | TYR 21 | - | VdWContact |
| TRP 23 | NTc.Cm10 | MET 24 | - | Hydrophobic |
| TRP 23 | NTc.Cm10 | MET 24 | - | VdWContact |
| SER 31 | NTc.Cm2 | ASP 181 | - | HBDonor |
| SER 31 | NTc.Cm2 | ASP 181 | - | VdWContact |
| SER 33 | CX.1 | ALA 180 | - | VdWContact |
| SER 35 | cxb1.1 | ASP 193 | 5.32x33 | HBDonor |
| SER 35 | cxb1.1 | ASP 193 | 5.32x33 | VdWContact |
| GLN 36 | cxb1.2 | ASP 193 | 5.32x33 | HBDonor |
| GLN 36 | cxb1.2 | ASP 193 | 5.32x33 | VdWContact |
| ILE 40 | cxb1.8 | PRO 27 | - | Hydrophobic |
| ARG 45 | cxb1.16 | TYR 21 | - | VdWContact |
| LYS 47 | B1.2 | TYR 21 | - | Hydrophobic |
| LYS 47 | B1.2 | GLU 26 | - | Cationic |
| LYS 47 | B1.2 | GLU 26 | - | HBDonor |
| LYS 47 | B1.2 | GLU 26 | - | VdWContact |
| LYS 48 | B1.3 | GLU 26 | - | VdWContact |
| LYS 48 | B1.3 | PRO 27 | - | Hydrophobic |
| LYS 48 | B1.3 | PRO 27 | - | VdWContact |
| LYS 48 | B1.3 | PHE 29 | - | Hydrophobic |
| LYS 48 | B1.3 | PHE 29 | - | VdWContact |
| VAL 49 | B1.4 | MET 24 | - | Hydrophobic |
| VAL 49 | B1.4 | MET 24 | - | VdWContact |
| VAL 49 | B1.4 | LYS 25 | - | VdWContact |
| CYS 50 | B1.5 | LYS 25 | - | HBDonor |
| CYS 50 | B1.5 | LYS 25 | - | Hydrophobic |
| CYS 50 | B1.5 | LYS 25 | - | VdWContact |
| CYS 50 | B1.5 | PRO 27 | - | VdWContact |
