Predicted complex interactions
CCL28_HUMAN + CXCR4
SUMMARY
- Chemokine
- CCL28_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 95
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 2 | NTc.Cm28 | PRO 191 | - | Hydrophobic |
| GLU 2 | NTc.Cm28 | PRO 191 | - | VdWContact |
| GLU 2 | NTc.Cm28 | ASN 192 | - | HBAcceptor |
| GLU 2 | NTc.Cm28 | ASN 192 | - | VdWContact |
| ILE 4 | NTc.Cm26 | PHE 174 | 4.63x64 | Hydrophobic |
| ILE 4 | NTc.Cm26 | PHE 189 | - | Hydrophobic |
| ILE 4 | NTc.Cm26 | PHE 189 | - | VdWContact |
| ILE 7 | NTc.Cm23 | VAL 177 | - | Hydrophobic |
| ILE 7 | NTc.Cm23 | SER 178 | - | VdWContact |
| ILE 7 | NTc.Cm23 | GLU 179 | - | Hydrophobic |
| ILE 7 | NTc.Cm23 | GLU 179 | - | VdWContact |
| ILE 7 | NTc.Cm23 | TYR 184 | - | Hydrophobic |
| ILE 7 | NTc.Cm23 | TYR 184 | - | VdWContact |
| SER 20 | NTc.Cm10 | ASP 193 | 5.32x33 | HBDonor |
| SER 20 | NTc.Cm10 | ASP 193 | 5.32x33 | VdWContact |
| SER 20 | NTc.Cm10 | LEU 266 | 6.62x62 | VdWContact |
| ARG 21 | NTc.Cm9 | SER 23 | - | HBDonor |
| ARG 21 | NTc.Cm9 | SER 23 | - | VdWContact |
| ARG 21 | NTc.Cm9 | GLU 268 | 6.64x64 | HBDonor |
| ARG 21 | NTc.Cm9 | GLU 268 | 6.64x64 | Hydrophobic |
| ARG 21 | NTc.Cm9 | GLU 268 | 6.64x64 | VdWContact |
| ARG 22 | NTc.Cm8 | PHE 264 | 6.60x60 | VdWContact |
| ARG 22 | NTc.Cm8 | ILE 265 | 6.61x61 | Hydrophobic |
| ARG 22 | NTc.Cm8 | ILE 265 | 6.61x61 | VdWContact |
| ARG 22 | NTc.Cm8 | LEU 266 | 6.62x62 | Hydrophobic |
| ARG 22 | NTc.Cm8 | LEU 266 | 6.62x62 | VdWContact |
| ARG 22 | NTc.Cm8 | LEU 267 | 6.63x63 | HBDonor |
| ARG 22 | NTc.Cm8 | LEU 267 | 6.63x63 | VdWContact |
| ARG 22 | NTc.Cm8 | GLU 268 | 6.64x64 | Hydrophobic |
| ARG 22 | NTc.Cm8 | GLU 268 | 6.64x64 | VdWContact |
| ARG 22 | NTc.Cm8 | ILE 269 | - | VdWContact |
| ARG 22 | NTc.Cm8 | ILE 270 | - | HBDonor |
| ARG 22 | NTc.Cm8 | ILE 270 | - | VdWContact |
| LEU 23 | NTc.Cm7 | ASP 193 | 5.32x33 | VdWContact |
| LEU 23 | NTc.Cm7 | LEU 266 | 6.62x62 | Hydrophobic |
| GLU 25 | NTc.Cm5 | LYS 25 | - | Anionic |
| GLU 25 | NTc.Cm5 | LYS 25 | - | HBAcceptor |
| GLU 25 | NTc.Cm5 | LYS 25 | - | Hydrophobic |
| GLU 25 | NTc.Cm5 | LYS 25 | - | VdWContact |
| GLU 25 | NTc.Cm5 | GLU 277 | 7.28x27 | Hydrophobic |
| GLU 25 | NTc.Cm5 | GLU 277 | 7.28x27 | VdWContact |
| ARG 26 | NTc.Cm4 | ARG 30 | 1.24x24 | VdWContact |
| ARG 26 | NTc.Cm4 | ASP 193 | 5.32x33 | Cationic |
| ARG 26 | NTc.Cm4 | VAL 196 | 5.35x36 | VdWContact |
| ARG 26 | NTc.Cm4 | ASP 262 | 6.58x58 | Cationic |
| ARG 26 | NTc.Cm4 | ASP 262 | 6.58x58 | HBDonor |
| ARG 26 | NTc.Cm4 | ASP 262 | 6.58x58 | VdWContact |
| ARG 26 | NTc.Cm4 | LEU 266 | 6.62x62 | VdWContact |
| ARG 26 | NTc.Cm4 | HIS 281 | 7.32x31 | Hydrophobic |
| ARG 26 | NTc.Cm4 | HIS 281 | 7.32x31 | VdWContact |
| VAL 27 | NTc.Cm3 | CYS 28 | - | VdWContact |
| ASN 28 | NTc.Cm2 | ARG 30 | 1.24x24 | Hydrophobic |
| ASN 28 | NTc.Cm2 | ARG 30 | 1.24x24 | VdWContact |
| MET 29 | NTc.Cm1 | ASP 181 | - | VdWContact |
| HIS 47 | B1.3 | ALA 180 | - | Hydrophobic |
| HIS 47 | B1.3 | ASP 181 | - | HBDonor |
| HIS 47 | B1.3 | ASP 181 | - | VdWContact |
| LYS 49 | B1.5 | HIS 281 | 7.32x31 | VdWContact |
| ARG 50 | B1.6 | ASP 97 | 2.63x63 | Cationic |
| ARG 50 | B1.6 | ASP 97 | 2.63x63 | HBDonor |
| ARG 50 | B1.6 | ASP 97 | 2.63x63 | VdWContact |
| ARG 50 | B1.6 | ILE 185 | - | Hydrophobic |
| ARG 50 | B1.6 | ILE 185 | - | VdWContact |
| ARG 51 | B1.7 | ASP 187 | 45.51x51 | Cationic |
| ARG 51 | B1.7 | ASP 187 | 45.51x51 | HBDonor |
| ARG 51 | B1.7 | ASP 187 | 45.51x51 | VdWContact |
| ARG 51 | B1.7 | ARG 188 | 45.52x52 | VdWContact |
| ARG 51 | B1.7 | PHE 189 | - | Hydrophobic |
| ARG 51 | B1.7 | PHE 189 | - | VdWContact |
| ARG 51 | B1.7 | TYR 190 | - | VdWContact |
| ARG 51 | B1.7 | VAL 196 | 5.35x36 | VdWContact |
| GLN 64 | B2.3 | MET 24 | - | Hydrophobic |
| GLN 64 | B2.3 | MET 24 | - | VdWContact |
| TRP 65 | B2.4 | PRO 27 | - | Hydrophobic |
| TRP 65 | B2.4 | PRO 27 | - | VdWContact |
| LYS 67 | B2.6 | MET 24 | - | Hydrophobic |
| VAL 68 | b2b3.2 | MET 24 | - | Hydrophobic |
| VAL 68 | b2b3.2 | MET 24 | - | VdWContact |
| VAL 68 | b2b3.2 | LYS 25 | - | VdWContact |
| VAL 68 | b2b3.2 | GLU 26 | - | Hydrophobic |
| VAL 68 | b2b3.2 | GLU 26 | - | VdWContact |
| GLN 69 | b2b3.11 | PRO 27 | - | HBDonor |
| GLN 69 | b2b3.11 | PRO 27 | - | Hydrophobic |
| GLN 69 | b2b3.11 | PRO 27 | - | VdWContact |
| LYS 72 | B3.2 | GLU 26 | - | Cationic |
| LYS 72 | B3.2 | GLU 26 | - | HBDonor |
| LYS 72 | B3.2 | GLU 26 | - | Hydrophobic |
| LYS 72 | B3.2 | GLU 26 | - | VdWContact |
| LYS 72 | B3.2 | PRO 27 | - | HBDonor |
| LYS 72 | B3.2 | CYS 274 | 7.25x24 | Cationic |
| LYS 72 | B3.2 | CYS 274 | 7.25x24 | VdWContact |
| GLY 77 | b3h.3 | PHE 29 | - | VdWContact |
| ASN 78 | b3h.4 | PHE 29 | - | VdWContact |
| VAL 79 | H.1 | PHE 29 | - | Hydrophobic |
| VAL 79 | H.1 | PHE 29 | - | VdWContact |
