Predicted complex interactions
CX3CL1_HUMAN + CXCR4
SUMMARY
- Chemokine
- CX3CL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 62
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm37 | ARG 188 | 45.52x52 | HBDonor |
| GLN 1 | NTc.Cm37 | ARG 188 | 45.52x52 | Hydrophobic |
| GLN 1 | NTc.Cm37 | ARG 188 | 45.52x52 | VdWContact |
| GLN 1 | NTc.Cm37 | VAL 196 | 5.35x36 | VdWContact |
| HIS 2 | NTc.Cm36 | TYR 45 | 1.39x39 | Hydrophobic |
| HIS 2 | NTc.Cm36 | TYR 45 | 1.39x39 | VdWContact |
| HIS 2 | NTc.Cm36 | TRP 94 | 2.60x60 | Hydrophobic |
| HIS 2 | NTc.Cm36 | TYR 116 | 3.32x32 | Hydrophobic |
| HIS 2 | NTc.Cm36 | GLU 288 | 7.39x38 | VdWContact |
| HIS 2 | NTc.Cm36 | PHE 292 | 7.43x42 | Hydrophobic |
| HIS 2 | NTc.Cm36 | PHE 292 | 7.43x42 | VdWContact |
| HIS 3 | NTc.Cm35 | GLN 200 | 5.39x40 | HBAcceptor |
| HIS 3 | NTc.Cm35 | GLN 200 | 5.39x40 | VdWContact |
| HIS 3 | NTc.Cm35 | ILE 259 | 6.55x55 | Hydrophobic |
| HIS 3 | NTc.Cm35 | ILE 259 | 6.55x55 | VdWContact |
| HIS 3 | NTc.Cm35 | ILE 284 | 7.35x34 | Hydrophobic |
| HIS 3 | NTc.Cm35 | ILE 284 | 7.35x34 | VdWContact |
| HIS 3 | NTc.Cm35 | GLU 288 | 7.39x38 | HBDonor |
| HIS 3 | NTc.Cm35 | GLU 288 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm34 | ASN 37 | 1.31x31 | VdWContact |
| GLY 4 | NTc.Cm34 | LEU 41 | 1.35x35 | VdWContact |
| GLY 4 | NTc.Cm34 | GLU 288 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm34 | GLU 288 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm33 | LEU 41 | 1.35x35 | Hydrophobic |
| VAL 5 | NTc.Cm33 | TRP 94 | 2.60x60 | Hydrophobic |
| VAL 5 | NTc.Cm33 | TRP 94 | 2.60x60 | VdWContact |
| VAL 5 | NTc.Cm33 | ALA 98 | 2.64x64 | Hydrophobic |
| THR 6 | NTc.Cm32 | ASP 187 | 45.51x51 | HBDonor |
| THR 6 | NTc.Cm32 | ASP 187 | 45.51x51 | VdWContact |
| LYS 7 | NTc.Cm31 | ASP 97 | 2.63x63 | Cationic |
| LYS 7 | NTc.Cm31 | ASP 97 | 2.63x63 | HBDonor |
| LYS 7 | NTc.Cm31 | ASP 97 | 2.63x63 | VdWContact |
| LYS 7 | NTc.Cm31 | ALA 100 | 2.66x66 | HBDonor |
| LYS 7 | NTc.Cm31 | ALA 100 | 2.66x66 | VdWContact |
| LYS 7 | NTc.Cm31 | ILE 185 | - | Hydrophobic |
| LYS 7 | NTc.Cm31 | ILE 185 | - | VdWContact |
| CYS 8 | NTc.Cm30 | ARG 30 | 1.24x24 | Anionic |
| CYS 8 | NTc.Cm30 | ARG 30 | 1.24x24 | VdWContact |
| ASN 9 | NTc.Cm29 | PHE 29 | - | VdWContact |
| ASN 9 | NTc.Cm29 | ARG 30 | 1.24x24 | HBAcceptor |
| ASN 9 | NTc.Cm29 | ARG 30 | 1.24x24 | VdWContact |
| ILE 10 | NTc.Cm28 | PRO 27 | - | Hydrophobic |
| ILE 10 | NTc.Cm28 | CYS 28 | - | VdWContact |
| ILE 10 | NTc.Cm28 | PHE 29 | - | Hydrophobic |
| THR 11 | NTc.Cm27 | CYS 28 | - | HBAcceptor |
| THR 11 | NTc.Cm27 | CYS 28 | - | HBDonor |
| THR 11 | NTc.Cm27 | CYS 28 | - | VdWContact |
| THR 11 | NTc.Cm27 | ARG 30 | 1.24x24 | VdWContact |
| LEU 23 | NTc.Cm15 | MET 16 | - | Hydrophobic |
| GLN 31 | NTc.Cm7 | ALA 180 | - | Hydrophobic |
| ALA 32 | NTc.Cm6 | ILE 185 | - | Hydrophobic |
| ALA 32 | NTc.Cm6 | PHE 189 | - | Hydrophobic |
| SER 33 | NTc.Cm5 | ILE 185 | - | VdWContact |
| SER 33 | NTc.Cm5 | PHE 189 | - | VdWContact |
| LYS 36 | NTc.Cm2 | ASP 193 | 5.32x33 | VdWContact |
| ILE 40 | CX.3 | PRO 27 | - | Hydrophobic |
| ARG 47 | cxb1.8 | GLU 26 | - | Cationic |
| LEU 48 | cxb1.10 | PRO 27 | - | Hydrophobic |
| LEU 48 | cxb1.10 | PRO 27 | - | VdWContact |
| LEU 48 | cxb1.10 | PHE 29 | - | Hydrophobic |
| LEU 48 | cxb1.10 | PHE 29 | - | VdWContact |
| PHE 49 | cxb1.11 | MET 24 | - | Hydrophobic |
