Predicted complex interactions
CXCL14_HUMAN + CXCR4
SUMMARY
- Chemokine
- CXCL14_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 76
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PRO 10 | NTc.Cm27 | ASP 181 | - | Hydrophobic |
| PRO 10 | NTc.Cm27 | ASP 181 | - | VdWContact |
| LYS 11 | NTc.Cm26 | GLU 179 | - | Cationic |
| LYS 11 | NTc.Cm26 | GLU 179 | - | HBDonor |
| LYS 11 | NTc.Cm26 | GLU 179 | - | VdWContact |
| LYS 11 | NTc.Cm26 | ASP 182 | - | Cationic |
| LYS 11 | NTc.Cm26 | ASP 182 | - | VdWContact |
| ARG 13 | NTc.Cm24 | GLU 179 | - | Cationic |
| ARG 13 | NTc.Cm24 | GLU 179 | - | HBDonor |
| ARG 13 | NTc.Cm24 | GLU 179 | - | VdWContact |
| LYS 18 | NTc.Cm19 | ASP 193 | 5.32x33 | Cationic |
| LYS 18 | NTc.Cm19 | ASP 193 | 5.32x33 | HBDonor |
| LYS 18 | NTc.Cm19 | ASP 193 | 5.32x33 | VdWContact |
| LYS 19 | NTc.Cm18 | GLU 2 | - | Cationic |
| MET 22 | NTc.Cm15 | TYR 12 | - | Hydrophobic |
| MET 22 | NTc.Cm15 | TYR 12 | - | VdWContact |
| MET 22 | NTc.Cm15 | MET 16 | - | Hydrophobic |
| LYS 23 | NTc.Cm14 | MET 24 | - | Hydrophobic |
| LYS 23 | NTc.Cm14 | MET 24 | - | VdWContact |
| LYS 23 | NTc.Cm14 | LYS 25 | - | HBDonor |
| LYS 23 | NTc.Cm14 | LYS 25 | - | VdWContact |
| LYS 23 | NTc.Cm14 | PRO 27 | - | Hydrophobic |
| LYS 23 | NTc.Cm14 | PRO 27 | - | VdWContact |
| LYS 25 | NTc.Cm12 | PRO 27 | - | VdWContact |
| LYS 25 | NTc.Cm12 | PHE 29 | - | Hydrophobic |
| TYR 26 | NTc.Cm11 | GLU 26 | - | Hydrophobic |
| TYR 26 | NTc.Cm11 | GLU 26 | - | VdWContact |
| TYR 26 | NTc.Cm11 | PHE 29 | - | Hydrophobic |
| PRO 27 | NTc.Cm10 | GLU 26 | - | VdWContact |
| LYS 32 | NTc.Cm5 | MET 16 | - | Hydrophobic |
| LYS 32 | NTc.Cm5 | MET 16 | - | VdWContact |
| LYS 32 | NTc.Cm5 | TYR 21 | - | HBDonor |
| LYS 32 | NTc.Cm5 | TYR 21 | - | VdWContact |
| ILE 35 | NTc.Cm2 | PRO 27 | - | Hydrophobic |
| ILE 35 | NTc.Cm2 | PRO 27 | - | VdWContact |
| ILE 35 | NTc.Cm2 | PHE 29 | - | Hydrophobic |
| VAL 41 | cxb1.2 | ILE 185 | - | Hydrophobic |
| VAL 41 | cxb1.2 | ILE 185 | - | VdWContact |
| VAL 41 | cxb1.2 | ASP 187 | 45.51x51 | VdWContact |
| VAL 41 | cxb1.2 | PHE 189 | - | Hydrophobic |
| VAL 41 | cxb1.2 | PHE 189 | - | VdWContact |
| SER 42 | cxb1.5 | ASP 187 | 45.51x51 | HBDonor |
| SER 42 | cxb1.5 | ASP 187 | 45.51x51 | VdWContact |
| ARG 43 | cxb1.6 | TYR 45 | 1.39x39 | HBDonor |
| ARG 43 | cxb1.6 | TYR 45 | 1.39x39 | VdWContact |
| ARG 43 | cxb1.6 | ASP 187 | 45.51x51 | HBDonor |
| ARG 43 | cxb1.6 | ASP 187 | 45.51x51 | VdWContact |
| ARG 43 | cxb1.6 | GLU 288 | 7.39x38 | Cationic |
| ARG 43 | cxb1.6 | GLU 288 | 7.39x38 | HBDonor |
| ARG 43 | cxb1.6 | GLU 288 | 7.39x38 | VdWContact |
| TYR 44 | cxb1.8 | HIS 281 | 7.32x31 | Hydrophobic |
| TYR 44 | cxb1.8 | ILE 284 | 7.35x34 | Hydrophobic |
| TYR 44 | cxb1.8 | SER 285 | 7.36x35 | VdWContact |
| TYR 44 | cxb1.8 | GLU 288 | 7.39x38 | HBDonor |
| TYR 44 | cxb1.8 | GLU 288 | 7.39x38 | VdWContact |
| ARG 45 | cxb1.10 | ARG 30 | 1.24x24 | HBAcceptor |
| ARG 45 | cxb1.10 | ARG 30 | 1.24x24 | VdWContact |
| ARG 45 | cxb1.10 | ASP 262 | 6.58x58 | Cationic |
| ARG 45 | cxb1.10 | ASP 262 | 6.58x58 | HBDonor |
| ARG 45 | cxb1.10 | ASP 262 | 6.58x58 | VdWContact |
| ARG 45 | cxb1.10 | ILE 265 | 6.61x61 | VdWContact |
| ARG 45 | cxb1.10 | LEU 266 | 6.62x62 | HBDonor |
| ARG 45 | cxb1.10 | LEU 266 | 6.62x62 | VdWContact |
| ARG 45 | cxb1.10 | GLU 277 | 7.28x27 | Cationic |
| ARG 45 | cxb1.10 | GLU 277 | 7.28x27 | HBDonor |
| ARG 45 | cxb1.10 | HIS 281 | 7.32x31 | Hydrophobic |
| ARG 45 | cxb1.10 | HIS 281 | 7.32x31 | VdWContact |
| GLN 47 | cxb1.14 | ARG 30 | 1.24x24 | Hydrophobic |
| GLU 48 | cxb1.15 | PRO 27 | - | VdWContact |
| GLU 48 | cxb1.15 | CYS 28 | - | HBAcceptor |
| GLU 48 | cxb1.15 | CYS 28 | - | HBDonor |
| GLU 48 | cxb1.15 | CYS 28 | - | VdWContact |
| GLU 48 | cxb1.15 | PHE 29 | - | VdWContact |
| CYS 50 | B1.1 | PHE 29 | - | Hydrophobic |
| CYS 50 | B1.1 | PHE 29 | - | VdWContact |
| ASN 69 | B2.2 | ILE 4 | - | VdWContact |
