Predicted complex interactions
CXCL17_HUMAN + CXCR4
SUMMARY
- Chemokine
- CXCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 104
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ARG 19 | NTc.Cm31 | ASP 22 | - | Cationic |
| ARG 19 | NTc.Cm31 | ASP 22 | - | HBDonor |
| ARG 19 | NTc.Cm31 | ASP 22 | - | VdWContact |
| LEU 22 | NTc.Cm28 | TYR 21 | - | Hydrophobic |
| LEU 22 | NTc.Cm28 | TYR 21 | - | VdWContact |
| LEU 22 | NTc.Cm28 | MET 24 | - | Hydrophobic |
| PHE 35 | NTc.Cm15 | PRO 191 | - | VdWContact |
| PHE 35 | NTc.Cm15 | ASN 192 | - | Hydrophobic |
| PHE 35 | NTc.Cm15 | ASN 192 | - | VdWContact |
| PHE 35 | NTc.Cm15 | ASP 193 | 5.32x33 | Hydrophobic |
| PHE 35 | NTc.Cm15 | ASP 193 | 5.32x33 | VdWContact |
| PHE 35 | NTc.Cm15 | LEU 194 | 5.33x34 | Hydrophobic |
| PHE 35 | NTc.Cm15 | LEU 194 | 5.33x34 | VdWContact |
| LEU 36 | NTc.Cm14 | PRO 191 | - | Hydrophobic |
| LEU 36 | NTc.Cm14 | PRO 191 | - | VdWContact |
| ALA 38 | NTc.Cm12 | PHE 189 | - | Hydrophobic |
| ALA 38 | NTc.Cm12 | PHE 189 | - | VdWContact |
| PRO 39 | NTc.Cm11 | SER 178 | - | VdWContact |
| GLY 61 | cxb1.15 | SER 178 | - | HBAcceptor |
| GLY 61 | cxb1.15 | SER 178 | - | VdWContact |
| GLY 61 | cxb1.15 | GLU 179 | - | VdWContact |
| ASN 62 | cxb1.16 | GLU 179 | - | VdWContact |
| ASN 62 | cxb1.16 | ALA 180 | - | Hydrophobic |
| ASN 62 | cxb1.16 | ALA 180 | - | VdWContact |
| VAL 63 | B1.2 | SER 178 | - | VdWContact |
| VAL 63 | B1.2 | ILE 185 | - | Hydrophobic |
| VAL 63 | B1.2 | ILE 185 | - | VdWContact |
| LYS 64 | B1.3 | SER 178 | - | VdWContact |
| LYS 64 | B1.3 | GLU 179 | - | Cationic |
| LYS 64 | B1.3 | GLU 179 | - | HBDonor |
| LYS 64 | B1.3 | GLU 179 | - | Hydrophobic |
| LYS 64 | B1.3 | GLU 179 | - | VdWContact |
| LYS 64 | B1.3 | ALA 180 | - | VdWContact |
| LYS 64 | B1.3 | ARG 183 | - | Hydrophobic |
| LYS 64 | B1.3 | ARG 183 | - | VdWContact |
| LYS 64 | B1.3 | TYR 184 | - | CationPi |
| LYS 64 | B1.3 | TYR 184 | - | HBDonor |
| LYS 64 | B1.3 | TYR 184 | - | Hydrophobic |
| LYS 64 | B1.3 | TYR 184 | - | VdWContact |
| LYS 64 | B1.3 | ILE 185 | - | VdWContact |
| LYS 65 | B1.4 | VAL 96 | 2.62x62 | VdWContact |
| LYS 65 | B1.4 | ASP 97 | 2.63x63 | Cationic |
| LYS 65 | B1.4 | ASP 97 | 2.63x63 | Hydrophobic |
| LYS 65 | B1.4 | ASP 97 | 2.63x63 | VdWContact |
| LYS 65 | B1.4 | ALA 100 | 2.66x66 | VdWContact |
| LYS 65 | B1.4 | ASN 101 | 23.49x49 | HBDonor |
| LYS 65 | B1.4 | ASN 101 | 23.49x49 | VdWContact |
| LYS 65 | B1.4 | TRP 102 | 23.50x50 | Hydrophobic |
| LYS 65 | B1.4 | TRP 102 | 23.50x50 | VdWContact |
| LYS 65 | B1.4 | ARG 183 | - | VdWContact |
| LYS 65 | B1.4 | TYR 184 | - | HBAcceptor |
| LYS 65 | B1.4 | TYR 184 | - | VdWContact |
| LYS 65 | B1.4 | ILE 185 | - | HBDonor |
| LYS 65 | B1.4 | ILE 185 | - | Hydrophobic |
| LYS 65 | B1.4 | ILE 185 | - | VdWContact |
| THR 66 | B1.5 | ASN 101 | 23.49x49 | VdWContact |
| THR 66 | B1.5 | ASP 182 | - | VdWContact |
| THR 66 | B1.5 | ARG 183 | - | VdWContact |
| ARG 67 | B1.6 | ALA 100 | 2.66x66 | Hydrophobic |
| ARG 67 | B1.6 | ASN 101 | 23.49x49 | HBDonor |
| ARG 67 | B1.6 | ASN 101 | 23.49x49 | VdWContact |
| GLN 69 | b1b2.2 | ARG 183 | - | HBAcceptor |
| GLN 69 | b1b2.2 | ARG 183 | - | VdWContact |
| ARG 73 | b1b2.7 | PHE 29 | - | Hydrophobic |
| ARG 73 | b1b2.7 | PHE 29 | - | VdWContact |
| PRO 75 | b1b2.9 | PHE 29 | - | Hydrophobic |
| PRO 75 | b1b2.9 | PHE 29 | - | VdWContact |
| SER 79 | b1b2.14 | PRO 27 | - | VdWContact |
| ARG 80 | b1b2.16 | GLU 26 | - | Cationic |
| ARG 80 | b1b2.16 | GLU 26 | - | HBDonor |
| ARG 80 | b1b2.16 | GLU 26 | - | Hydrophobic |
| ARG 80 | b1b2.16 | GLU 26 | - | VdWContact |
| ARG 80 | b1b2.16 | PRO 27 | - | VdWContact |
| CYS 82 | b1b2.18 | PRO 27 | - | Hydrophobic |
| CYS 82 | b1b2.18 | PRO 27 | - | VdWContact |
| GLN 83 | b1b2.19 | LYS 25 | - | VdWContact |
| GLN 83 | b1b2.19 | PRO 27 | - | Hydrophobic |
| GLN 83 | b1b2.19 | PRO 27 | - | VdWContact |
| GLN 83 | b1b2.19 | CYS 28 | - | VdWContact |
| GLN 83 | b1b2.19 | GLU 277 | 7.28x27 | VdWContact |
| GLN 84 | b1b2.20 | MET 24 | - | HBDonor |
| GLN 84 | b1b2.20 | MET 24 | - | Hydrophobic |
| GLN 84 | b1b2.20 | MET 24 | - | VdWContact |
| GLN 84 | b1b2.20 | LYS 25 | - | VdWContact |
| GLN 84 | b1b2.20 | GLU 26 | - | Hydrophobic |
| PHE 85 | b1b2.21 | MET 24 | - | Hydrophobic |
| LYS 87 | b1b2.23 | LYS 25 | - | Hydrophobic |
| LYS 87 | b1b2.23 | LYS 25 | - | VdWContact |
| LYS 87 | b1b2.23 | GLU 268 | 6.64x64 | VdWContact |
| LYS 87 | b1b2.23 | GLN 272 | - | VdWContact |
| LYS 87 | b1b2.23 | GLU 277 | 7.28x27 | Cationic |
| LYS 87 | b1b2.23 | GLU 277 | 7.28x27 | HBDonor |
| LYS 87 | b1b2.23 | GLU 277 | 7.28x27 | VdWContact |
| GLN 88 | b1b2.24 | MET 24 | - | Hydrophobic |
| GLN 88 | b1b2.24 | MET 24 | - | VdWContact |
| GLN 90 | B2.1 | ILE 265 | 6.61x61 | VdWContact |
| GLN 90 | B2.1 | LEU 266 | 6.62x62 | VdWContact |
| GLN 90 | B2.1 | GLU 268 | 6.64x64 | HBAcceptor |
| GLN 90 | B2.1 | GLU 268 | 6.64x64 | Hydrophobic |
| GLN 90 | B2.1 | GLU 268 | 6.64x64 | VdWContact |
| LEU 91 | B2.2 | GLU 268 | 6.64x64 | HBDonor |
| LEU 91 | B2.2 | GLU 268 | 6.64x64 | VdWContact |
| PHE 94 | B2.5 | LEU 267 | 6.63x63 | Hydrophobic |
| PHE 94 | B2.5 | LEU 267 | 6.63x63 | VdWContact |
