Predicted complex interactions
CXCL9_HUMAN + CXCR4
SUMMARY
- Chemokine
- CXCL9_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 85
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 1 | NTc.Cm30 | LEU 41 | 1.35x35 | Hydrophobic |
| THR 1 | NTc.Cm30 | GLU 288 | 7.39x38 | HBDonor |
| THR 1 | NTc.Cm30 | GLU 288 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm29 | TRP 94 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm29 | TRP 94 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm29 | TYR 116 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm29 | ARG 188 | 45.52x52 | HBAcceptor |
| PRO 2 | NTc.Cm29 | ARG 188 | 45.52x52 | VdWContact |
| PRO 2 | NTc.Cm29 | GLU 288 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm29 | PHE 292 | 7.43x42 | Hydrophobic |
| VAL 3 | NTc.Cm28 | TYR 116 | 3.32x32 | Hydrophobic |
| VAL 3 | NTc.Cm28 | TYR 116 | 3.32x32 | VdWContact |
| VAL 3 | NTc.Cm28 | HIS 203 | 5.42x43 | Hydrophobic |
| VAL 3 | NTc.Cm28 | HIS 203 | 5.42x43 | VdWContact |
| VAL 3 | NTc.Cm28 | TYR 255 | 6.51x51 | Hydrophobic |
| VAL 3 | NTc.Cm28 | TYR 255 | 6.51x51 | VdWContact |
| VAL 3 | NTc.Cm28 | ILE 259 | 6.55x55 | Hydrophobic |
| VAL 3 | NTc.Cm28 | GLU 288 | 7.39x38 | HBDonor |
| VAL 3 | NTc.Cm28 | GLU 288 | 7.39x38 | VdWContact |
| VAL 4 | NTc.Cm27 | HIS 281 | 7.32x31 | Hydrophobic |
| VAL 4 | NTc.Cm27 | ILE 284 | 7.35x34 | Hydrophobic |
| VAL 4 | NTc.Cm27 | ILE 284 | 7.35x34 | VdWContact |
| ARG 5 | NTc.Cm26 | ASP 187 | 45.51x51 | VdWContact |
| ARG 5 | NTc.Cm26 | ASP 193 | 5.32x33 | Cationic |
| ARG 5 | NTc.Cm26 | ASP 193 | 5.32x33 | HBDonor |
| ARG 5 | NTc.Cm26 | ASP 193 | 5.32x33 | VdWContact |
| LYS 6 | NTc.Cm25 | ASP 97 | 2.63x63 | Cationic |
| LYS 6 | NTc.Cm25 | ASP 97 | 2.63x63 | HBDonor |
| LYS 6 | NTc.Cm25 | ASP 97 | 2.63x63 | VdWContact |
| LYS 6 | NTc.Cm25 | ILE 185 | - | Hydrophobic |
| LYS 6 | NTc.Cm25 | ASP 187 | 45.51x51 | HBDonor |
| LYS 6 | NTc.Cm25 | ASP 187 | 45.51x51 | VdWContact |
| ARG 8 | NTc.Cm23 | ASP 262 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm23 | ASP 262 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm23 | ASP 262 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm23 | LEU 266 | 6.62x62 | VdWContact |
| ARG 8 | NTc.Cm23 | HIS 281 | 7.32x31 | VdWContact |
| CYS 9 | NTc.Cm22 | ARG 30 | 1.24x24 | HBAcceptor |
| CYS 9 | NTc.Cm22 | ARG 30 | 1.24x24 | VdWContact |
| SER 10 | NTc.Cm21 | CYS 28 | - | HBAcceptor |
| SER 10 | NTc.Cm21 | CYS 28 | - | VdWContact |
| ILE 12 | NTc.Cm19 | CYS 28 | - | Hydrophobic |
| ILE 12 | NTc.Cm19 | CYS 274 | 7.25x24 | Hydrophobic |
| ILE 12 | NTc.Cm19 | GLU 277 | 7.28x27 | Hydrophobic |
| HIS 20 | NTc.Cm11 | MET 16 | - | Hydrophobic |
| HIS 20 | NTc.Cm11 | MET 16 | - | VdWContact |
| GLN 22 | NTc.Cm9 | TYR 12 | - | Hydrophobic |
| GLN 22 | NTc.Cm9 | GLU 14 | - | HBDonor |
| GLN 22 | NTc.Cm9 | GLU 14 | - | VdWContact |
| SER 23 | NTc.Cm8 | MET 16 | - | VdWContact |
| PRO 34 | cxb1.1 | PHE 189 | - | Hydrophobic |
| PRO 34 | cxb1.1 | PHE 189 | - | VdWContact |
| GLU 37 | cxb1.6 | ASN 192 | - | VdWContact |
| GLU 37 | cxb1.6 | ASP 193 | 5.32x33 | HBAcceptor |
| GLU 37 | cxb1.6 | ASP 193 | 5.32x33 | VdWContact |
| LYS 38 | cxb1.7 | GLU 268 | 6.64x64 | Cationic |
| ILE 42 | cxb1.14 | PRO 27 | - | Hydrophobic |
| ILE 42 | cxb1.14 | PHE 29 | - | Hydrophobic |
| LEU 45 | B1.1 | TYR 21 | - | Hydrophobic |
| LEU 45 | B1.1 | TYR 21 | - | VdWContact |
| LEU 45 | B1.1 | MET 24 | - | Hydrophobic |
| LEU 45 | B1.1 | MET 24 | - | VdWContact |
| ASN 47 | B1.3 | TYR 21 | - | VdWContact |
| VAL 49 | B1.5 | MET 24 | - | Hydrophobic |
| VAL 49 | B1.5 | GLU 26 | - | VdWContact |
| GLN 50 | B1.6 | GLU 26 | - | VdWContact |
| GLN 50 | B1.6 | PRO 27 | - | Hydrophobic |
| GLN 50 | B1.6 | PHE 29 | - | VdWContact |
| THR 51 | B1.7 | MET 24 | - | Hydrophobic |
| THR 51 | B1.7 | LYS 25 | - | HBDonor |
| THR 51 | B1.7 | LYS 25 | - | VdWContact |
| CYS 52 | b1b2.4 | LYS 25 | - | HBDonor |
| CYS 52 | b1b2.4 | LYS 25 | - | VdWContact |
| TRP 67 | B2.6 | TYR 7 | - | Hydrophobic |
| GLN 70 | b2b3.11 | SER 9 | - | VdWContact |
| VAL 71 | b2b3.12 | TYR 7 | - | Hydrophobic |
| VAL 71 | b2b3.12 | TYR 7 | - | VdWContact |
| LYS 74 | B3.3 | TYR 7 | - | HBDonor |
| LYS 74 | B3.3 | TYR 7 | - | Hydrophobic |
| LYS 74 | B3.3 | TYR 7 | - | VdWContact |
| LYS 74 | B3.3 | THR 8 | - | VdWContact |
| LYS 74 | B3.3 | SER 9 | - | HBDonor |
| LYS 74 | B3.3 | SER 9 | - | VdWContact |
| LYS 75 | B3.4 | TYR 7 | - | Hydrophobic |
| LYS 75 | B3.4 | TYR 7 | - | VdWContact |
