Predicted complex interactions
XCL1_HUMAN + CXCR4
SUMMARY
- Chemokine
- XCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR4 View partner entry
- Partner description
- UniProt: P61073; Gene: cxcr4_human; Family: Chemokine
- Interactions detected
- 64
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 16 | NTc.Cm15 | GLU 268 | 6.64x64 | HBDonor |
| THR 16 | NTc.Cm15 | GLU 268 | 6.64x64 | VdWContact |
| GLN 17 | NTc.Cm14 | ILE 265 | 6.61x61 | VdWContact |
| GLN 17 | NTc.Cm14 | LEU 266 | 6.62x62 | VdWContact |
| ARG 18 | NTc.Cm13 | MET 24 | - | VdWContact |
| ARG 18 | NTc.Cm13 | LYS 25 | - | Hydrophobic |
| ARG 18 | NTc.Cm13 | LYS 25 | - | VdWContact |
| ARG 18 | NTc.Cm13 | GLU 26 | - | Cationic |
| ARG 18 | NTc.Cm13 | GLU 26 | - | HBDonor |
| ARG 18 | NTc.Cm13 | GLU 26 | - | VdWContact |
| ARG 18 | NTc.Cm13 | PRO 27 | - | Hydrophobic |
| ARG 18 | NTc.Cm13 | PRO 27 | - | VdWContact |
| ARG 18 | NTc.Cm13 | CYS 28 | - | HBAcceptor |
| PRO 20 | NTc.Cm11 | CYS 28 | - | VdWContact |
| PRO 20 | NTc.Cm11 | ARG 30 | 1.24x24 | Hydrophobic |
| PRO 20 | NTc.Cm11 | ARG 30 | 1.24x24 | VdWContact |
| VAL 21 | NTc.Cm10 | PHE 29 | - | Hydrophobic |
| VAL 21 | NTc.Cm10 | PHE 29 | - | VdWContact |
| SER 22 | NTc.Cm9 | ARG 30 | 1.24x24 | VdWContact |
| LYS 25 | NTc.Cm6 | SER 178 | - | HBDonor |
| LYS 25 | NTc.Cm6 | SER 178 | - | VdWContact |
| LYS 25 | NTc.Cm6 | GLU 179 | - | Cationic |
| LYS 25 | NTc.Cm6 | GLU 179 | - | HBDonor |
| LYS 25 | NTc.Cm6 | GLU 179 | - | VdWContact |
| LYS 25 | NTc.Cm6 | ALA 180 | - | Hydrophobic |
| LYS 25 | NTc.Cm6 | ALA 180 | - | VdWContact |
| LYS 25 | NTc.Cm6 | ASP 181 | - | HBAcceptor |
| LYS 25 | NTc.Cm6 | ASP 181 | - | VdWContact |
| LYS 42 | cxb1.15 | SER 178 | - | HBAcceptor |
| LYS 42 | cxb1.15 | SER 178 | - | VdWContact |
| LYS 42 | cxb1.15 | ALA 180 | - | Hydrophobic |
| LYS 42 | cxb1.15 | ALA 180 | - | VdWContact |
| LYS 42 | cxb1.15 | ASP 181 | - | Cationic |
| LYS 42 | cxb1.15 | ASP 181 | - | HBDonor |
| LYS 42 | cxb1.15 | ASP 181 | - | VdWContact |
| LYS 42 | cxb1.15 | ILE 185 | - | Hydrophobic |
| LYS 42 | cxb1.15 | ILE 185 | - | VdWContact |
| ARG 43 | cxb1.16 | ASP 187 | 45.51x51 | Cationic |
| ARG 43 | cxb1.16 | ASP 187 | 45.51x51 | HBDonor |
| ARG 43 | cxb1.16 | ASP 187 | 45.51x51 | Hydrophobic |
| ARG 43 | cxb1.16 | ASP 187 | 45.51x51 | VdWContact |
| ARG 43 | cxb1.16 | ARG 188 | 45.52x52 | HBDonor |
| ARG 43 | cxb1.16 | ARG 188 | 45.52x52 | VdWContact |
| ARG 43 | cxb1.16 | PHE 189 | - | Hydrophobic |
| ARG 43 | cxb1.16 | PHE 189 | - | VdWContact |
| LEU 45 | B1.2 | TYR 190 | - | VdWContact |
| THR 54 | b1b2.13 | MET 24 | - | Hydrophobic |
| THR 54 | b1b2.13 | MET 24 | - | VdWContact |
| TRP 55 | b1b2.14 | PRO 27 | - | Hydrophobic |
| TRP 55 | b1b2.14 | PRO 27 | - | VdWContact |
| ASP 58 | B2.2 | PRO 27 | - | Hydrophobic |
| ASP 58 | B2.2 | PRO 27 | - | VdWContact |
| ASP 58 | B2.2 | PHE 29 | - | Hydrophobic |
| ASP 58 | B2.2 | PHE 29 | - | VdWContact |
| VAL 59 | B2.3 | PRO 27 | - | Hydrophobic |
| SER 62 | B2.6 | PHE 29 | - | VdWContact |
| LYS 66 | b2b3.12 | GLU 31 | 1.25x25 | Cationic |
| LYS 66 | b2b3.12 | GLU 31 | 1.25x25 | HBDonor |
| LYS 66 | b2b3.12 | GLU 31 | 1.25x25 | VdWContact |
| LYS 66 | b2b3.12 | ASP 181 | - | Cationic |
| LYS 66 | b2b3.12 | ASP 181 | - | HBDonor |
| LYS 66 | b2b3.12 | ASP 181 | - | VdWContact |
| ARG 70 | B3.4 | ASP 182 | - | Cationic |
| ARG 70 | B3.4 | ASP 182 | - | VdWContact |
