Predicted complex interactions
CCL1_HUMAN + CXCR5
SUMMARY
- Chemokine
- CCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 93
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 2 | NTc.Cm31 | THR 305 | 7.36x35 | VdWContact |
| SER 2 | NTc.Cm31 | GLU 308 | 7.39x38 | HBDonor |
| SER 2 | NTc.Cm31 | GLU 308 | 7.39x38 | VdWContact |
| MET 3 | NTc.Cm30 | ILE 103 | 2.56x56 | Hydrophobic |
| MET 3 | NTc.Cm30 | ILE 103 | 2.56x56 | VdWContact |
| MET 3 | NTc.Cm30 | ALA 107 | 2.60x60 | Hydrophobic |
| MET 3 | NTc.Cm30 | ALA 107 | 2.60x60 | VdWContact |
| MET 3 | NTc.Cm30 | VAL 125 | 3.28x28 | Hydrophobic |
| MET 3 | NTc.Cm30 | VAL 125 | 3.28x28 | VdWContact |
| MET 3 | NTc.Cm30 | HIS 129 | 3.32x32 | Hydrophobic |
| MET 3 | NTc.Cm30 | GLU 308 | 7.39x38 | HBDonor |
| MET 3 | NTc.Cm30 | GLU 308 | 7.39x38 | VdWContact |
| GLN 4 | NTc.Cm29 | ILE 126 | 3.29x29 | HBDonor |
| GLN 4 | NTc.Cm29 | ILE 126 | 3.29x29 | VdWContact |
| GLN 4 | NTc.Cm29 | HIS 129 | 3.32x32 | Hydrophobic |
| GLN 4 | NTc.Cm29 | HIS 129 | 3.32x32 | VdWContact |
| GLN 4 | NTc.Cm29 | LYS 130 | 3.33x33 | VdWContact |
| GLN 4 | NTc.Cm29 | TYR 275 | 6.51x51 | VdWContact |
| GLN 4 | NTc.Cm29 | GLU 308 | 7.39x38 | HBDonor |
| GLN 4 | NTc.Cm29 | GLU 308 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm28 | ARG 219 | 5.39x40 | VdWContact |
| VAL 5 | NTc.Cm28 | ILE 279 | 6.55x55 | Hydrophobic |
| VAL 5 | NTc.Cm28 | ILE 304 | 7.35x34 | Hydrophobic |
| VAL 5 | NTc.Cm28 | ILE 304 | 7.35x34 | VdWContact |
| PRO 6 | NTc.Cm27 | THR 203 | 45.51x51 | Hydrophobic |
| PRO 6 | NTc.Cm27 | GLN 206 | - | VdWContact |
| PRO 6 | NTc.Cm27 | ARG 286 | 6.62x62 | HBAcceptor |
| PRO 6 | NTc.Cm27 | ARG 286 | 6.62x62 | VdWContact |
| PHE 7 | NTc.Cm26 | PRO 301 | 7.32x31 | Hydrophobic |
| PHE 7 | NTc.Cm26 | PRO 301 | 7.32x31 | VdWContact |
| PHE 7 | NTc.Cm26 | ILE 304 | 7.35x34 | Hydrophobic |
| SER 8 | NTc.Cm25 | ARG 286 | 6.62x62 | VdWContact |
| ARG 9 | NTc.Cm24 | LEU 37 | - | Hydrophobic |
| ARG 9 | NTc.Cm24 | LEU 37 | - | VdWContact |
| PHE 12 | NTc.Cm21 | ASN 292 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | ASN 292 | - | VdWContact |
| PHE 12 | NTc.Cm21 | ASN 297 | 7.28x27 | Hydrophobic |
| PHE 12 | NTc.Cm21 | ASN 297 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm20 | HIS 36 | - | HBAcceptor |
| SER 13 | NTc.Cm20 | HIS 36 | - | HBDonor |
| SER 13 | NTc.Cm20 | HIS 36 | - | VdWContact |
| ALA 15 | NTc.Cm18 | HIS 36 | - | Hydrophobic |
| ALA 15 | NTc.Cm18 | HIS 36 | - | VdWContact |
| ILE 19 | NTc.Cm14 | VAL 33 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | TYR 27 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | TYR 27 | - | VdWContact |
| ARG 22 | NTc.Cm11 | TYR 27 | - | CationPi |
| ARG 22 | NTc.Cm11 | TYR 27 | - | HBDonor |
| ARG 22 | NTc.Cm11 | TYR 27 | - | Hydrophobic |
| ARG 22 | NTc.Cm11 | TYR 27 | - | VdWContact |
| LEU 25 | NTc.Cm8 | TRP 19 | - | Hydrophobic |
| LEU 25 | NTc.Cm8 | TRP 19 | - | VdWContact |
| ARG 28 | NTc.Cm5 | HIS 194 | - | Hydrophobic |
| ARG 28 | NTc.Cm5 | HIS 194 | - | VdWContact |
| SER 31 | NTc.Cm2 | GLN 206 | - | HBDonor |
| SER 31 | NTc.Cm2 | GLN 206 | - | VdWContact |
| SER 32 | NTc.Cm1 | GLN 206 | - | HBDonor |
| SER 32 | NTc.Cm1 | GLN 206 | - | VdWContact |
| SER 32 | NTc.Cm1 | THR 212 | - | VdWContact |
| ILE 33 | CX.1 | GLN 206 | - | Hydrophobic |
| ILE 33 | CX.1 | GLN 206 | - | VdWContact |
| ILE 33 | CX.1 | TRP 215 | 5.35x36 | Hydrophobic |
| ILE 33 | CX.1 | ARG 286 | 6.62x62 | Hydrophobic |
| ILE 33 | CX.1 | ARG 286 | 6.62x62 | VdWContact |
| SER 35 | cxb1.1 | ARG 286 | 6.62x62 | VdWContact |
| SER 35 | cxb1.1 | LYS 288 | 6.64x64 | HBAcceptor |
| SER 35 | cxb1.1 | LYS 288 | 6.64x64 | VdWContact |
| ASN 36 | cxb1.2 | LYS 288 | 6.64x64 | HBAcceptor |
| ASN 36 | cxb1.2 | LYS 288 | 6.64x64 | VdWContact |
| ILE 40 | cxb1.8 | LEU 37 | - | Hydrophobic |
| LEU 43 | cxb1.14 | VAL 33 | - | Hydrophobic |
| LEU 43 | cxb1.14 | VAL 33 | - | VdWContact |
| LYS 44 | cxb1.15 | TRP 19 | - | Hydrophobic |
| LYS 44 | cxb1.15 | TRP 19 | - | VdWContact |
| LYS 44 | cxb1.15 | ASP 22 | - | Cationic |
| LYS 44 | cxb1.15 | ASP 22 | - | HBDonor |
| LYS 44 | cxb1.15 | ASP 22 | - | VdWContact |
| ARG 45 | cxb1.16 | TYR 27 | - | HBDonor |
| ARG 45 | cxb1.16 | TYR 27 | - | VdWContact |
| LYS 47 | B1.2 | VAL 33 | - | HBDonor |
| LYS 47 | B1.2 | VAL 33 | - | VdWContact |
| GLU 48 | B1.3 | LEU 37 | - | Hydrophobic |
| GLU 48 | B1.3 | HIS 195 | - | HBAcceptor |
| GLU 48 | B1.3 | HIS 195 | - | VdWContact |
| ALA 49 | B1.4 | VAL 33 | - | Hydrophobic |
| ALA 49 | B1.4 | VAL 33 | - | VdWContact |
| ALA 49 | B1.4 | HIS 36 | - | Hydrophobic |
| CYS 50 | B1.5 | HIS 36 | - | Hydrophobic |
| CYS 50 | B1.5 | HIS 36 | - | VdWContact |
| CYS 50 | B1.5 | LEU 37 | - | VdWContact |
| SER 70 | b2b3.12 | HIS 194 | - | VdWContact |
| LYS 71 | B3.1 | ASN 196 | - | Hydrophobic |
| LYS 71 | B3.1 | ASN 196 | - | VdWContact |
