Predicted complex interactions
XCL2_HUMAN + ACKR2
SUMMARY
- Chemokine
- XCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 72
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm30 | TRP 102 | 2.60x60 | Hydrophobic |
| VAL 1 | NTc.Cm30 | TYR 124 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm30 | TYR 124 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm30 | GLU 298 | 7.39x38 | Cationic |
| VAL 1 | NTc.Cm30 | GLU 298 | 7.39x38 | VdWContact |
| VAL 1 | NTc.Cm30 | PHE 302 | 7.43x42 | Hydrophobic |
| GLY 2 | NTc.Cm29 | GLU 298 | 7.39x38 | HBDonor |
| GLY 2 | NTc.Cm29 | GLU 298 | 7.39x38 | VdWContact |
| GLU 4 | NTc.Cm27 | LYS 207 | 5.35x36 | Anionic |
| GLU 4 | NTc.Cm27 | LYS 207 | 5.35x36 | HBAcceptor |
| GLU 4 | NTc.Cm27 | LYS 207 | 5.35x36 | VdWContact |
| GLU 4 | NTc.Cm27 | ARG 211 | 5.39x40 | Anionic |
| GLU 4 | NTc.Cm27 | ARG 211 | 5.39x40 | HBAcceptor |
| GLU 4 | NTc.Cm27 | ARG 211 | 5.39x40 | VdWContact |
| SER 6 | NTc.Cm25 | LYS 38 | 1.24x24 | VdWContact |
| SER 6 | NTc.Cm25 | ASP 291 | 7.32x31 | HBDonor |
| SER 6 | NTc.Cm25 | ASP 291 | 7.32x31 | VdWContact |
| HIS 7 | NTc.Cm24 | HIS 196 | 45.51x51 | Hydrophobic |
| ARG 8 | NTc.Cm23 | ARG 37 | - | VdWContact |
| ARG 8 | NTc.Cm23 | LYS 38 | 1.24x24 | HBAcceptor |
| ARG 8 | NTc.Cm23 | LYS 38 | 1.24x24 | VdWContact |
| ARG 8 | NTc.Cm23 | ASP 39 | 1.25x25 | Cationic |
| ARG 8 | NTc.Cm23 | ASP 39 | 1.25x25 | VdWContact |
| ARG 8 | NTc.Cm23 | VAL 42 | 1.28x28 | Hydrophobic |
| ARG 9 | NTc.Cm22 | LEU 35 | - | Hydrophobic |
| ARG 9 | NTc.Cm22 | LEU 35 | - | VdWContact |
| ARG 9 | NTc.Cm22 | CYS 36 | - | VdWContact |
| THR 10 | NTc.Cm21 | CYS 36 | - | HBAcceptor |
| THR 10 | NTc.Cm21 | CYS 36 | - | HBDonor |
| THR 10 | NTc.Cm21 | CYS 36 | - | VdWContact |
| THR 10 | NTc.Cm21 | LYS 38 | 1.24x24 | HBAcceptor |
| THR 10 | NTc.Cm21 | LYS 38 | 1.24x24 | VdWContact |
| VAL 12 | NTc.Cm19 | CYS 36 | - | Hydrophobic |
| VAL 12 | NTc.Cm19 | CYS 36 | - | VdWContact |
| VAL 12 | NTc.Cm19 | CYS 284 | 7.25x24 | Hydrophobic |
| VAL 12 | NTc.Cm19 | SER 287 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm18 | MET 34 | - | VdWContact |
| LEU 14 | NTc.Cm17 | GLN 279 | 6.64x64 | VdWContact |
| THR 15 | NTc.Cm16 | VAL 31 | - | Hydrophobic |
| THR 15 | NTc.Cm16 | VAL 31 | - | VdWContact |
| THR 15 | NTc.Cm16 | MET 34 | - | Hydrophobic |
| THR 15 | NTc.Cm16 | MET 34 | - | VdWContact |
| GLN 17 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| GLN 17 | NTc.Cm14 | TYR 27 | - | VdWContact |
| ARG 18 | NTc.Cm13 | TYR 24 | - | HBAcceptor |
| ARG 18 | NTc.Cm13 | TYR 24 | - | VdWContact |
| LEU 19 | NTc.Cm12 | TYR 24 | - | Hydrophobic |
| LEU 19 | NTc.Cm12 | TYR 24 | - | VdWContact |
| LEU 19 | NTc.Cm12 | LEU 28 | - | Hydrophobic |
| PRO 20 | NTc.Cm11 | TYR 24 | - | Hydrophobic |
| PRO 20 | NTc.Cm11 | TYR 24 | - | VdWContact |
| ARG 23 | NTc.Cm8 | SER 21 | - | VdWContact |
| ARG 23 | NTc.Cm8 | TYR 24 | - | CationPi |
| ARG 23 | NTc.Cm8 | TYR 24 | - | VdWContact |
| ARG 23 | NTc.Cm8 | LEU 28 | - | VdWContact |
| SER 33 | cxb1.1 | LYS 207 | 5.35x36 | VdWContact |
| ILE 38 | cxb1.8 | LEU 35 | - | Hydrophobic |
| ILE 38 | cxb1.8 | LEU 35 | - | VdWContact |
| THR 41 | cxb1.14 | LEU 28 | - | Hydrophobic |
| ARG 43 | cxb1.16 | TYR 25 | - | CationPi |
| ARG 43 | cxb1.16 | TYR 25 | - | VdWContact |
| LEU 45 | B1.2 | LEU 28 | - | Hydrophobic |
| LEU 45 | B1.2 | LEU 28 | - | VdWContact |
| LEU 45 | B1.2 | ALA 32 | - | Hydrophobic |
| LEU 45 | B1.2 | ALA 32 | - | VdWContact |
| LYS 46 | B1.3 | LEU 35 | - | Hydrophobic |
| LYS 46 | B1.3 | LEU 35 | - | VdWContact |
| VAL 47 | B1.4 | VAL 31 | - | Hydrophobic |
| VAL 47 | B1.4 | VAL 31 | - | VdWContact |
| CYS 48 | B1.5 | MET 34 | - | Hydrophobic |
| CYS 48 | B1.5 | MET 34 | - | VdWContact |
| CYS 48 | B1.5 | LEU 35 | - | VdWContact |
