Predicted complex interactions
CCL17_HUMAN + CXCR5
SUMMARY
- Chemokine
- CCL17_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 92
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm32 | TYR 58 | 1.39x39 | Hydrophobic |
| ALA 1 | NTc.Cm32 | TYR 58 | 1.39x39 | VdWContact |
| ALA 1 | NTc.Cm32 | ALA 107 | 2.60x60 | Hydrophobic |
| ALA 1 | NTc.Cm32 | ALA 107 | 2.60x60 | VdWContact |
| ALA 1 | NTc.Cm32 | GLU 308 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm32 | GLU 308 | 7.39x38 | HBDonor |
| ALA 1 | NTc.Cm32 | GLU 308 | 7.39x38 | VdWContact |
| ARG 2 | NTc.Cm31 | ASP 282 | 6.58x58 | Cationic |
| ARG 2 | NTc.Cm31 | PRO 301 | 7.32x31 | VdWContact |
| ARG 2 | NTc.Cm31 | ILE 304 | 7.35x34 | VdWContact |
| ARG 2 | NTc.Cm31 | THR 305 | 7.36x35 | VdWContact |
| ARG 2 | NTc.Cm31 | GLU 308 | 7.39x38 | HBDonor |
| GLY 3 | NTc.Cm30 | GLY 111 | 2.64x64 | VdWContact |
| THR 4 | NTc.Cm29 | LYS 50 | 1.31x31 | Hydrophobic |
| THR 4 | NTc.Cm29 | ALA 51 | 1.32x32 | Hydrophobic |
| THR 4 | NTc.Cm29 | GLY 111 | 2.64x64 | HBDonor |
| THR 4 | NTc.Cm29 | GLY 111 | 2.64x64 | VdWContact |
| THR 4 | NTc.Cm29 | ARG 201 | - | HBAcceptor |
| THR 4 | NTc.Cm29 | ARG 201 | - | VdWContact |
| ASN 5 | NTc.Cm28 | ARG 201 | - | VdWContact |
| GLY 7 | NTc.Cm26 | ALA 40 | - | VdWContact |
| GLU 9 | NTc.Cm24 | LEU 37 | - | Hydrophobic |
| GLU 9 | NTc.Cm24 | LEU 37 | - | VdWContact |
| GLU 9 | NTc.Cm24 | CYS 38 | - | VdWContact |
| GLU 9 | NTc.Cm24 | ALA 40 | - | Hydrophobic |
| CYS 10 | NTc.Cm23 | CYS 38 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 38 | - | VdWContact |
| CYS 10 | NTc.Cm23 | ASN 297 | 7.28x27 | Hydrophobic |
| CYS 11 | NTc.Cm22 | HIS 36 | - | VdWContact |
| LEU 12 | NTc.Cm21 | HIS 36 | - | HBDonor |
| LEU 12 | NTc.Cm21 | HIS 36 | - | Hydrophobic |
| LEU 12 | NTc.Cm21 | HIS 36 | - | VdWContact |
| LEU 12 | NTc.Cm21 | CYS 38 | - | VdWContact |
| LEU 12 | NTc.Cm21 | ASN 292 | - | VdWContact |
| LEU 12 | NTc.Cm21 | THR 293 | 7.24x23 | VdWContact |
| LEU 12 | NTc.Cm21 | CYS 294 | 7.25x24 | VdWContact |
| GLU 13 | NTc.Cm20 | HIS 36 | - | Hydrophobic |
| GLU 13 | NTc.Cm20 | HIS 36 | - | VdWContact |
| PHE 15 | NTc.Cm18 | SER 31 | - | VdWContact |
| PHE 15 | NTc.Cm18 | VAL 33 | - | Hydrophobic |
| ALA 18 | NTc.Cm15 | ASP 29 | - | VdWContact |
| ILE 19 | NTc.Cm14 | ASN 26 | - | VdWContact |
| PRO 20 | NTc.Cm13 | ASN 26 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | ASN 26 | - | VdWContact |
| LEU 21 | NTc.Cm12 | TRP 19 | - | Hydrophobic |
| LEU 21 | NTc.Cm12 | TRP 19 | - | VdWContact |
| LEU 21 | NTc.Cm12 | ASP 22 | - | Hydrophobic |
| LEU 21 | NTc.Cm12 | ARG 23 | - | Hydrophobic |
| ARG 22 | NTc.Cm11 | ARG 23 | - | Hydrophobic |
| ARG 22 | NTc.Cm11 | TYR 27 | - | VdWContact |
| LYS 23 | NTc.Cm10 | ASN 26 | - | HBDonor |
| LYS 23 | NTc.Cm10 | ASN 26 | - | VdWContact |
| LYS 23 | NTc.Cm10 | TYR 27 | - | HBDonor |
| LYS 23 | NTc.Cm10 | TYR 27 | - | VdWContact |
| TRP 27 | NTc.Cm6 | HIS 194 | - | Hydrophobic |
| TRP 27 | NTc.Cm6 | HIS 194 | - | VdWContact |
| TRP 27 | NTc.Cm6 | HIS 195 | - | Hydrophobic |
| TRP 27 | NTc.Cm6 | HIS 195 | - | PiStacking |
| TRP 27 | NTc.Cm6 | HIS 195 | - | VdWContact |
| TYR 28 | NTc.Cm5 | HIS 194 | - | VdWContact |
| TYR 28 | NTc.Cm5 | HIS 195 | - | Hydrophobic |
| TYR 28 | NTc.Cm5 | ASN 196 | - | Hydrophobic |
| GLN 29 | NTc.Cm4 | HIS 194 | - | HBDonor |
| GLN 29 | NTc.Cm4 | HIS 194 | - | VdWContact |
| GLN 29 | NTc.Cm4 | ASN 196 | - | HBAcceptor |
| GLN 29 | NTc.Cm4 | ASN 196 | - | VdWContact |
| GLU 32 | NTc.Cm1 | SER 191 | - | VdWContact |
| GLU 32 | NTc.Cm1 | ARG 286 | 6.62x62 | HBAcceptor |
| GLU 32 | NTc.Cm1 | ARG 286 | 6.62x62 | VdWContact |
| ASP 33 | CX.1 | ARG 286 | 6.62x62 | Anionic |
| ASP 33 | CX.1 | ARG 286 | 6.62x62 | HBAcceptor |
| ASP 33 | CX.1 | ARG 286 | 6.62x62 | VdWContact |
| SER 35 | cxb1.1 | ASN 297 | 7.28x27 | HBDonor |
| SER 35 | cxb1.1 | ASN 297 | 7.28x27 | VdWContact |
| VAL 40 | cxb1.8 | LEU 37 | - | Hydrophobic |
| ARG 47 | B1.2 | VAL 33 | - | Hydrophobic |
| ALA 48 | B1.3 | LEU 37 | - | Hydrophobic |
| ILE 49 | B1.4 | VAL 33 | - | Hydrophobic |
| ILE 49 | B1.4 | VAL 33 | - | VdWContact |
| CYS 50 | B1.5 | HIS 36 | - | Hydrophobic |
| LYS 56 | b1b2.10 | GLU 15 | - | Cationic |
| LYS 56 | b1b2.10 | GLU 15 | - | HBDonor |
| LYS 56 | b1b2.10 | GLU 15 | - | VdWContact |
| ARG 57 | b1b2.12 | ASP 22 | - | Cationic |
| ASN 60 | b1b2.16 | TRP 19 | - | Hydrophobic |
| ALA 61 | B2.1 | TRP 19 | - | Hydrophobic |
| ALA 61 | B2.1 | TRP 19 | - | VdWContact |
| TYR 64 | B2.4 | TRP 19 | - | Hydrophobic |
| TYR 64 | B2.4 | TRP 19 | - | VdWContact |
| TYR 64 | B2.4 | ARG 23 | - | VdWContact |
| GLU 69 | b2b3.11 | HIS 195 | - | HBAcceptor |
| GLU 69 | b2b3.11 | HIS 195 | - | VdWContact |
