Predicted complex interactions
CCL19_HUMAN + CXCR5
SUMMARY
- Chemokine
- CCL19_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 86
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 5 | NTc.Cm24 | PRO 39 | - | Hydrophobic |
| GLU 6 | NTc.Cm23 | ALA 40 | - | HBAcceptor |
| GLU 6 | NTc.Cm23 | ALA 40 | - | Hydrophobic |
| GLU 6 | NTc.Cm23 | ALA 40 | - | VdWContact |
| GLU 6 | NTc.Cm23 | HIS 195 | - | Hydrophobic |
| GLU 6 | NTc.Cm23 | HIS 195 | - | VdWContact |
| ASP 7 | NTc.Cm22 | LEU 37 | - | Hydrophobic |
| ASP 7 | NTc.Cm22 | CYS 38 | - | VdWContact |
| CYS 8 | NTc.Cm21 | LEU 37 | - | VdWContact |
| CYS 8 | NTc.Cm21 | CYS 38 | - | HBAcceptor |
| CYS 8 | NTc.Cm21 | CYS 38 | - | HBDonor |
| CYS 8 | NTc.Cm21 | CYS 38 | - | VdWContact |
| CYS 8 | NTc.Cm21 | ALA 40 | - | Hydrophobic |
| CYS 8 | NTc.Cm21 | ALA 40 | - | VdWContact |
| LEU 10 | NTc.Cm19 | HIS 36 | - | HBDonor |
| LEU 10 | NTc.Cm19 | HIS 36 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | HIS 36 | - | VdWContact |
| LEU 10 | NTc.Cm19 | CYS 38 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | CYS 38 | - | VdWContact |
| LEU 10 | NTc.Cm19 | ASN 292 | - | HBAcceptor |
| LEU 10 | NTc.Cm19 | ASN 292 | - | VdWContact |
| LEU 10 | NTc.Cm19 | THR 293 | 7.24x23 | VdWContact |
| LEU 10 | NTc.Cm19 | ASN 297 | 7.28x27 | Hydrophobic |
| LEU 10 | NTc.Cm19 | ASN 297 | 7.28x27 | VdWContact |
| SER 11 | NTc.Cm18 | LYS 288 | 6.64x64 | VdWContact |
| VAL 12 | NTc.Cm17 | LYS 288 | 6.64x64 | HBAcceptor |
| VAL 12 | NTc.Cm17 | LYS 288 | 6.64x64 | VdWContact |
| ILE 17 | NTc.Cm12 | LEU 32 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TYR 27 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TYR 27 | - | VdWContact |
| TYR 20 | NTc.Cm9 | GLU 20 | - | Hydrophobic |
| TYR 20 | NTc.Cm9 | GLU 20 | - | VdWContact |
| TYR 20 | NTc.Cm9 | ARG 23 | - | HBDonor |
| TYR 20 | NTc.Cm9 | ARG 23 | - | Hydrophobic |
| TYR 20 | NTc.Cm9 | ARG 23 | - | VdWContact |
| TYR 20 | NTc.Cm9 | LEU 24 | - | Hydrophobic |
| TYR 20 | NTc.Cm9 | LEU 24 | - | VdWContact |
| ILE 21 | NTc.Cm8 | LEU 24 | - | Hydrophobic |
| ILE 21 | NTc.Cm8 | LEU 32 | - | Hydrophobic |
| TYR 27 | NTc.Cm2 | HIS 194 | - | Hydrophobic |
| TYR 27 | NTc.Cm2 | HIS 194 | - | VdWContact |
| LEU 28 | NTc.Cm1 | LEU 37 | - | Hydrophobic |
| LEU 29 | CX.1 | HIS 194 | - | Hydrophobic |
| LEU 29 | CX.1 | HIS 194 | - | VdWContact |
| LEU 29 | CX.1 | GLU 207 | - | Hydrophobic |
| ILE 30 | CX.5 | THR 203 | 45.51x51 | Hydrophobic |
| ILE 30 | CX.5 | GLN 206 | - | Hydrophobic |
| ILE 30 | CX.5 | GLN 206 | - | VdWContact |
| LYS 31 | cxb1.1 | SER 191 | - | VdWContact |
| LYS 31 | cxb1.1 | GLN 192 | - | VdWContact |
| LYS 31 | cxb1.1 | GLY 193 | - | VdWContact |
| LYS 31 | cxb1.1 | HIS 194 | - | HBDonor |
| LYS 31 | cxb1.1 | HIS 194 | - | VdWContact |
| LYS 31 | cxb1.1 | GLU 207 | - | Cationic |
| ASP 32 | cxb1.2 | GLY 193 | - | VdWContact |
| ASP 32 | cxb1.2 | HIS 194 | - | HBAcceptor |
| ASP 32 | cxb1.2 | HIS 194 | - | VdWContact |
| ARG 35 | cxb1.8 | ASP 282 | 6.58x58 | Cationic |
| ARG 35 | cxb1.8 | ASP 282 | 6.58x58 | HBDonor |
| ARG 35 | cxb1.8 | ASP 282 | 6.58x58 | VdWContact |
| ARG 35 | cxb1.8 | ALA 285 | 6.61x61 | VdWContact |
| ARG 35 | cxb1.8 | ARG 286 | 6.62x62 | VdWContact |
| ARG 35 | cxb1.8 | ASN 297 | 7.28x27 | HBDonor |
| ARG 35 | cxb1.8 | ASN 297 | 7.28x27 | VdWContact |
| PRO 37 | cxb1.10 | GLN 206 | - | Hydrophobic |
| VAL 40 | cxb1.15 | LEU 37 | - | Hydrophobic |
| ARG 45 | B1.4 | ASP 25 | - | Cationic |
| ARG 45 | B1.4 | ASN 28 | - | HBDonor |
| ARG 45 | B1.4 | ASN 28 | - | VdWContact |
| ARG 47 | B1.6 | THR 30 | - | HBDonor |
| ARG 47 | B1.6 | THR 30 | - | VdWContact |
| ARG 47 | B1.6 | LEU 32 | - | HBDonor |
| ARG 47 | B1.6 | LEU 32 | - | VdWContact |
| ARG 47 | B1.6 | GLU 34 | - | VdWContact |
| GLN 48 | B1.7 | ASN 35 | - | VdWContact |
| GLN 48 | B1.7 | LEU 37 | - | Hydrophobic |
| LEU 49 | b1b2.4 | LEU 32 | - | Hydrophobic |
| LEU 49 | b1b2.4 | ASN 35 | - | Hydrophobic |
| LEU 49 | b1b2.4 | ASN 35 | - | VdWContact |
| CYS 50 | b1b2.6 | ASN 35 | - | HBDonor |
| CYS 50 | b1b2.6 | ASN 35 | - | VdWContact |
| ASP 54 | b1b2.10 | GLN 209 | - | Hydrophobic |
| ASP 54 | b1b2.10 | GLN 209 | - | VdWContact |
| ARG 64 | B2.6 | GLU 20 | - | Cationic |
| ARG 64 | B2.6 | GLU 20 | - | HBDonor |
| ARG 64 | B2.6 | GLU 20 | - | VdWContact |
