Predicted complex interactions
CCL2_HUMAN + CXCR5
SUMMARY
- Chemokine
- CCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 85
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | LYS 50 | 1.31x31 | HBAcceptor |
| GLN 1 | NTc.Cm33 | LYS 50 | 1.31x31 | VdWContact |
| GLN 1 | NTc.Cm33 | GLU 110 | 2.63x63 | Cationic |
| GLN 1 | NTc.Cm33 | GLU 110 | 2.63x63 | VdWContact |
| GLN 1 | NTc.Cm33 | THR 305 | 7.36x35 | HBDonor |
| GLN 1 | NTc.Cm33 | THR 305 | 7.36x35 | VdWContact |
| GLN 1 | NTc.Cm33 | GLU 308 | 7.39x38 | HBDonor |
| GLN 1 | NTc.Cm33 | GLU 308 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm32 | ILE 126 | 3.29x29 | Hydrophobic |
| PRO 2 | NTc.Cm32 | HIS 129 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLU 308 | 7.39x38 | VdWContact |
| ASP 3 | NTc.Cm31 | LYS 130 | 3.33x33 | Anionic |
| ASP 3 | NTc.Cm31 | LYS 130 | 3.33x33 | HBAcceptor |
| ASP 3 | NTc.Cm31 | LYS 130 | 3.33x33 | VdWContact |
| ASP 3 | NTc.Cm31 | ARG 219 | 5.39x40 | Anionic |
| ASP 3 | NTc.Cm31 | ARG 219 | 5.39x40 | HBAcceptor |
| ASP 3 | NTc.Cm31 | ARG 219 | 5.39x40 | VdWContact |
| ASP 3 | NTc.Cm31 | TYR 275 | 6.51x51 | HBAcceptor |
| ASP 3 | NTc.Cm31 | TYR 275 | 6.51x51 | Hydrophobic |
| ASP 3 | NTc.Cm31 | TYR 275 | 6.51x51 | VdWContact |
| ALA 4 | NTc.Cm30 | ILE 304 | 7.35x34 | Hydrophobic |
| ILE 5 | NTc.Cm29 | ASP 282 | 6.58x58 | VdWContact |
| ILE 5 | NTc.Cm29 | ARG 286 | 6.62x62 | VdWContact |
| ILE 5 | NTc.Cm29 | PRO 301 | 7.32x31 | Hydrophobic |
| ILE 5 | NTc.Cm29 | ILE 304 | 7.35x34 | Hydrophobic |
| ASN 6 | NTc.Cm28 | LYS 50 | 1.31x31 | VdWContact |
| ASN 6 | NTc.Cm28 | ARG 201 | - | HBAcceptor |
| ASN 6 | NTc.Cm28 | ARG 201 | - | VdWContact |
| ALA 7 | NTc.Cm27 | ARG 201 | - | VdWContact |
| PRO 8 | NTc.Cm26 | ALA 40 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | ALA 40 | - | VdWContact |
| PRO 8 | NTc.Cm26 | THR 41 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | ARG 201 | - | VdWContact |
| VAL 9 | NTc.Cm25 | ALA 40 | - | VdWContact |
| THR 10 | NTc.Cm24 | LEU 37 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | LEU 37 | - | VdWContact |
| THR 10 | NTc.Cm24 | PRO 39 | - | VdWContact |
| CYS 11 | NTc.Cm23 | HIS 36 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 38 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 38 | - | VdWContact |
| CYS 12 | NTc.Cm22 | HIS 36 | - | VdWContact |
| TYR 13 | NTc.Cm21 | HIS 36 | - | HBDonor |
| TYR 13 | NTc.Cm21 | HIS 36 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | HIS 36 | - | VdWContact |
| TYR 13 | NTc.Cm21 | CYS 38 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | CYS 38 | - | VdWContact |
| TYR 13 | NTc.Cm21 | ASN 292 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | ASN 292 | - | VdWContact |
| TYR 13 | NTc.Cm21 | ASN 297 | 7.28x27 | HBDonor |
| TYR 13 | NTc.Cm21 | ASN 297 | 7.28x27 | Hydrophobic |
| TYR 13 | NTc.Cm21 | ASN 297 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | VAL 33 | - | Hydrophobic |
| ASN 14 | NTc.Cm20 | HIS 36 | - | Hydrophobic |
| PHE 15 | NTc.Cm19 | VAL 33 | - | VdWContact |
| ARG 18 | NTc.Cm16 | TYR 27 | - | CationPi |
| ARG 18 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | ASP 29 | - | Cationic |
| ARG 18 | NTc.Cm16 | ASP 29 | - | HBDonor |
| ARG 18 | NTc.Cm16 | ASP 29 | - | VdWContact |
| ARG 24 | NTc.Cm10 | GLU 20 | - | Cationic |
| ARG 24 | NTc.Cm10 | GLU 20 | - | HBDonor |
| ARG 24 | NTc.Cm10 | GLU 20 | - | VdWContact |
| ARG 24 | NTc.Cm10 | LEU 24 | - | VdWContact |
| ARG 29 | NTc.Cm5 | HIS 195 | - | HBDonor |
| ARG 29 | NTc.Cm5 | HIS 195 | - | VdWContact |
| SER 34 | CX.1 | GLN 206 | - | VdWContact |
| SER 34 | CX.1 | THR 212 | - | HBDonor |
| SER 34 | CX.1 | THR 212 | - | VdWContact |
| SER 34 | CX.1 | ARG 286 | 6.62x62 | HBAcceptor |
| SER 34 | CX.1 | ARG 286 | 6.62x62 | VdWContact |
| LYS 35 | CX.5 | GLN 206 | - | VdWContact |
| PRO 37 | cxb1.2 | LYS 288 | 6.64x64 | Hydrophobic |
| PRO 37 | cxb1.2 | LYS 288 | 6.64x64 | VdWContact |
| PRO 37 | cxb1.2 | ASN 292 | - | Hydrophobic |
| PRO 37 | cxb1.2 | ASN 292 | - | VdWContact |
| ILE 42 | cxb1.10 | LEU 37 | - | Hydrophobic |
| VAL 47 | B1.1 | LEU 24 | - | Hydrophobic |
| GLU 50 | B1.4 | LEU 37 | - | Hydrophobic |
| GLU 50 | B1.4 | LEU 37 | - | VdWContact |
| GLU 50 | B1.4 | HIS 195 | - | VdWContact |
| ILE 51 | B1.5 | ASN 35 | - | VdWContact |
| CYS 52 | B1.6 | ASN 35 | - | HBDonor |
| CYS 52 | B1.6 | ASN 35 | - | VdWContact |
| CYS 52 | B1.6 | LEU 37 | - | Hydrophobic |
| CYS 52 | B1.6 | LEU 37 | - | VdWContact |
