Predicted complex interactions
CCL21_HUMAN + CXCR5
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 90
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm30 | GLU 110 | 2.63x63 | HBDonor |
| SER 1 | NTc.Cm30 | GLU 110 | 2.63x63 | VdWContact |
| SER 1 | NTc.Cm30 | GLU 308 | 7.39x38 | Cationic |
| SER 1 | NTc.Cm30 | GLU 308 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm30 | GLU 308 | 7.39x38 | VdWContact |
| ASP 2 | NTc.Cm29 | LYS 50 | 1.31x31 | Anionic |
| ASP 2 | NTc.Cm29 | LYS 50 | 1.31x31 | VdWContact |
| ASP 2 | NTc.Cm29 | THR 305 | 7.36x35 | HBAcceptor |
| ASP 2 | NTc.Cm29 | THR 305 | 7.36x35 | VdWContact |
| GLY 3 | NTc.Cm28 | ARG 201 | - | VdWContact |
| GLY 4 | NTc.Cm27 | ARG 201 | - | HBAcceptor |
| GLY 4 | NTc.Cm27 | ARG 201 | - | VdWContact |
| ALA 5 | NTc.Cm26 | ALA 40 | - | Hydrophobic |
| ALA 5 | NTc.Cm26 | ALA 40 | - | VdWContact |
| ALA 5 | NTc.Cm26 | GLU 42 | - | Hydrophobic |
| ALA 5 | NTc.Cm26 | GLU 42 | - | VdWContact |
| GLN 6 | NTc.Cm25 | ALA 40 | - | VdWContact |
| GLN 6 | NTc.Cm25 | SER 198 | - | VdWContact |
| ASP 7 | NTc.Cm24 | LEU 37 | - | Hydrophobic |
| ASP 7 | NTc.Cm24 | CYS 38 | - | VdWContact |
| ASP 7 | NTc.Cm24 | PRO 39 | - | VdWContact |
| ASP 7 | NTc.Cm24 | ALA 40 | - | HBAcceptor |
| ASP 7 | NTc.Cm24 | ALA 40 | - | VdWContact |
| CYS 8 | NTc.Cm23 | CYS 38 | - | HBAcceptor |
| CYS 8 | NTc.Cm23 | CYS 38 | - | HBDonor |
| CYS 8 | NTc.Cm23 | CYS 38 | - | VdWContact |
| LEU 10 | NTc.Cm21 | CYS 38 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | CYS 38 | - | VdWContact |
| LEU 10 | NTc.Cm21 | ASN 297 | 7.28x27 | Hydrophobic |
| LEU 10 | NTc.Cm21 | ASN 297 | 7.28x27 | VdWContact |
| LYS 11 | NTc.Cm20 | HIS 36 | - | Hydrophobic |
| LYS 11 | NTc.Cm20 | HIS 36 | - | VdWContact |
| SER 13 | NTc.Cm18 | GLU 34 | - | VdWContact |
| GLN 14 | NTc.Cm17 | GLU 34 | - | HBDonor |
| GLN 14 | NTc.Cm17 | GLU 34 | - | VdWContact |
| ARG 15 | NTc.Cm16 | ASP 29 | - | Cationic |
| ARG 15 | NTc.Cm16 | GLU 34 | - | Cationic |
| ILE 17 | NTc.Cm14 | VAL 33 | - | Hydrophobic |
| ALA 19 | NTc.Cm12 | TRP 19 | - | Hydrophobic |
| ALA 19 | NTc.Cm12 | TRP 19 | - | VdWContact |
| LYS 20 | NTc.Cm11 | ASP 22 | - | HBDonor |
| LYS 20 | NTc.Cm11 | ASP 22 | - | VdWContact |
| LYS 20 | NTc.Cm11 | ARG 23 | - | HBDonor |
| LYS 20 | NTc.Cm11 | ARG 23 | - | Hydrophobic |
| LYS 20 | NTc.Cm11 | ARG 23 | - | VdWContact |
| LYS 20 | NTc.Cm11 | ASN 26 | - | HBDonor |
| LYS 20 | NTc.Cm11 | ASN 26 | - | VdWContact |
| LYS 20 | NTc.Cm11 | TYR 27 | - | HBDonor |
| LYS 20 | NTc.Cm11 | TYR 27 | - | VdWContact |
| ARG 26 | NTc.Cm5 | HIS 194 | - | Hydrophobic |
| ARG 26 | NTc.Cm5 | HIS 194 | - | VdWContact |
| ARG 26 | NTc.Cm5 | ASN 196 | - | VdWContact |
| LYS 27 | NTc.Cm4 | HIS 194 | - | HBDonor |
| LYS 27 | NTc.Cm4 | HIS 194 | - | Hydrophobic |
| LYS 27 | NTc.Cm4 | HIS 194 | - | VdWContact |
| GLU 29 | NTc.Cm2 | GLU 207 | - | Hydrophobic |
| PRO 30 | NTc.Cm1 | GLN 206 | - | Hydrophobic |
| PRO 30 | NTc.Cm1 | GLN 206 | - | VdWContact |
| LEU 32 | CX.5 | ILE 304 | 7.35x34 | Hydrophobic |
| LEU 32 | CX.5 | ILE 304 | 7.35x34 | VdWContact |
| GLY 33 | cxb1.1 | ASN 297 | 7.28x27 | VdWContact |
| GLY 33 | cxb1.1 | PRO 301 | 7.32x31 | VdWContact |
| SER 35 | cxb1.5 | ASN 292 | - | VdWContact |
| LEU 40 | cxb1.11 | LEU 37 | - | Hydrophobic |
| LEU 42 | cxb1.15 | ASN 196 | - | VdWContact |
| ALA 49 | B1.6 | ASN 35 | - | VdWContact |
| ALA 49 | B1.6 | LEU 37 | - | Hydrophobic |
| GLU 50 | B1.7 | LEU 37 | - | Hydrophobic |
| GLU 50 | B1.7 | ASN 196 | - | HBAcceptor |
| GLU 50 | B1.7 | ASN 196 | - | VdWContact |
| LEU 51 | b1b2.4 | VAL 33 | - | Hydrophobic |
| LEU 51 | b1b2.4 | VAL 33 | - | VdWContact |
| CYS 52 | b1b2.6 | HIS 36 | - | Hydrophobic |
| GLN 62 | B2.2 | GLU 15 | - | HBDonor |
| GLN 62 | B2.2 | GLU 15 | - | VdWContact |
| LEU 63 | B2.3 | TRP 19 | - | Hydrophobic |
| HIS 66 | B2.6 | TRP 19 | - | Hydrophobic |
| HIS 66 | B2.6 | TRP 19 | - | PiStacking |
| LYS 69 | b2b3.9 | GLU 12 | - | Cationic |
| LYS 69 | b2b3.9 | GLU 12 | - | HBDonor |
| LYS 69 | b2b3.9 | GLU 12 | - | VdWContact |
| PRO 73 | B3.1 | HIS 195 | - | VdWContact |
| GLN 74 | B3.2 | HIS 195 | - | VdWContact |
| LYS 75 | B3.3 | GLY 193 | - | HBDonor |
| LYS 75 | B3.3 | GLY 193 | - | VdWContact |
| LYS 75 | B3.3 | HIS 194 | - | HBDonor |
| LYS 75 | B3.3 | HIS 194 | - | VdWContact |
| LYS 75 | B3.3 | HIS 195 | - | HBDonor |
| LYS 75 | B3.3 | HIS 195 | - | Hydrophobic |
| LYS 75 | B3.3 | HIS 195 | - | VdWContact |
