Predicted complex interactions
CCL22_HUMAN + CXCR5
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 94
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | GLU 110 | 2.63x63 | Cationic |
| GLY 1 | NTc.Cm35 | GLU 110 | 2.63x63 | VdWContact |
| GLY 1 | NTc.Cm35 | ILE 126 | 3.29x29 | VdWContact |
| GLY 1 | NTc.Cm35 | CYS 202 | 45.50x50 | HBDonor |
| GLY 1 | NTc.Cm35 | CYS 202 | 45.50x50 | VdWContact |
| PRO 2 | NTc.Cm34 | ALA 107 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | HIS 129 | 3.32x32 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 275 | 6.51x51 | VdWContact |
| TYR 3 | NTc.Cm33 | ILE 304 | 7.35x34 | Hydrophobic |
| TYR 3 | NTc.Cm33 | GLU 308 | 7.39x38 | HBDonor |
| TYR 3 | NTc.Cm33 | GLU 308 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm32 | LYS 50 | 1.31x31 | VdWContact |
| GLY 4 | NTc.Cm32 | THR 305 | 7.36x35 | HBAcceptor |
| GLY 4 | NTc.Cm32 | THR 305 | 7.36x35 | VdWContact |
| ALA 5 | NTc.Cm31 | VAL 54 | 1.35x35 | Hydrophobic |
| ALA 5 | NTc.Cm31 | THR 305 | 7.36x35 | Hydrophobic |
| ASN 6 | NTc.Cm30 | GLY 111 | 2.64x64 | HBDonor |
| ASN 6 | NTc.Cm30 | GLY 111 | 2.64x64 | VdWContact |
| ASN 6 | NTc.Cm30 | ARG 201 | - | HBAcceptor |
| ASN 6 | NTc.Cm30 | ARG 201 | - | VdWContact |
| MET 7 | NTc.Cm29 | GLU 42 | - | VdWContact |
| MET 7 | NTc.Cm29 | PRO 301 | 7.32x31 | Hydrophobic |
| MET 7 | NTc.Cm29 | PRO 301 | 7.32x31 | VdWContact |
| GLU 8 | NTc.Cm28 | ARG 201 | - | Anionic |
| GLU 8 | NTc.Cm28 | ARG 201 | - | HBAcceptor |
| GLU 8 | NTc.Cm28 | ARG 201 | - | VdWContact |
| ASP 9 | NTc.Cm27 | ALA 40 | - | VdWContact |
| ASP 9 | NTc.Cm27 | THR 41 | - | Hydrophobic |
| ASP 9 | NTc.Cm27 | THR 41 | - | VdWContact |
| ASP 9 | NTc.Cm27 | GLU 42 | - | HBAcceptor |
| ASP 9 | NTc.Cm27 | GLU 42 | - | VdWContact |
| SER 10 | NTc.Cm26 | ALA 40 | - | VdWContact |
| VAL 11 | NTc.Cm25 | LEU 37 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | LEU 37 | - | VdWContact |
| CYS 12 | NTc.Cm24 | CYS 38 | - | HBAcceptor |
| CYS 12 | NTc.Cm24 | CYS 38 | - | HBDonor |
| CYS 12 | NTc.Cm24 | CYS 38 | - | VdWContact |
| ARG 14 | NTc.Cm22 | GLU 34 | - | Cationic |
| ARG 14 | NTc.Cm22 | GLU 34 | - | HBDonor |
| ARG 14 | NTc.Cm22 | GLU 34 | - | VdWContact |
| ARG 14 | NTc.Cm22 | HIS 36 | - | HBDonor |
| ARG 14 | NTc.Cm22 | HIS 36 | - | VdWContact |
| ARG 14 | NTc.Cm22 | ASN 292 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | ASN 292 | - | VdWContact |
| ARG 14 | NTc.Cm22 | ASN 297 | 7.28x27 | VdWContact |
| ASP 15 | NTc.Cm21 | HIS 36 | - | Hydrophobic |
| ASP 15 | NTc.Cm21 | HIS 36 | - | VdWContact |
| ASP 15 | NTc.Cm21 | LYS 288 | 6.64x64 | Anionic |
| ASP 15 | NTc.Cm21 | LYS 288 | 6.64x64 | HBAcceptor |
| ASP 15 | NTc.Cm21 | LYS 288 | 6.64x64 | VdWContact |
| ARG 20 | NTc.Cm16 | ASP 16 | - | Cationic |
| ARG 20 | NTc.Cm16 | TRP 19 | - | Hydrophobic |
| ARG 20 | NTc.Cm16 | ARG 23 | - | HBAcceptor |
| ARG 20 | NTc.Cm16 | ARG 23 | - | VdWContact |
| LEU 21 | NTc.Cm15 | TYR 27 | - | Hydrophobic |
| LEU 21 | NTc.Cm15 | TYR 27 | - | VdWContact |
| PRO 22 | NTc.Cm14 | ARG 23 | - | VdWContact |
| PRO 22 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | TYR 27 | - | VdWContact |
| ARG 24 | NTc.Cm12 | ASP 16 | - | HBDonor |
| ARG 24 | NTc.Cm12 | ASP 16 | - | VdWContact |
| ARG 24 | NTc.Cm12 | GLU 20 | - | Cationic |
| ARG 24 | NTc.Cm12 | GLU 20 | - | HBDonor |
| ARG 24 | NTc.Cm12 | GLU 20 | - | VdWContact |
| VAL 25 | NTc.Cm11 | TYR 27 | - | Hydrophobic |
| VAL 25 | NTc.Cm11 | TYR 27 | - | VdWContact |
| TYR 30 | NTc.Cm6 | LEU 37 | - | Hydrophobic |
| TRP 31 | NTc.Cm5 | HIS 195 | - | Hydrophobic |
| TRP 31 | NTc.Cm5 | HIS 195 | - | PiStacking |
| TRP 31 | NTc.Cm5 | HIS 195 | - | VdWContact |
| TRP 31 | NTc.Cm5 | ASN 196 | - | HBAcceptor |
| TRP 31 | NTc.Cm5 | ASN 196 | - | VdWContact |
| THR 32 | NTc.Cm4 | ASN 196 | - | VdWContact |
| ASP 34 | NTc.Cm2 | SER 191 | - | VdWContact |
| ASP 34 | NTc.Cm2 | GLY 193 | - | VdWContact |
| ASP 34 | NTc.Cm2 | SER 198 | - | HBAcceptor |
| ASP 34 | NTc.Cm2 | SER 198 | - | VdWContact |
| SER 35 | NTc.Cm1 | ARG 201 | - | VdWContact |
| PRO 37 | CX.5 | ARG 286 | 6.62x62 | VdWContact |
| ARG 38 | cxb1.1 | ARG 286 | 6.62x62 | HBDonor |
| ARG 38 | cxb1.1 | ARG 286 | 6.62x62 | VdWContact |
| ARG 38 | cxb1.1 | LYS 288 | 6.64x64 | VdWContact |
| VAL 42 | cxb1.7 | LEU 37 | - | Hydrophobic |
| VAL 42 | cxb1.7 | LEU 37 | - | VdWContact |
| ARG 47 | cxb1.15 | TYR 27 | - | HBDonor |
| LYS 49 | B1.1 | VAL 33 | - | Hydrophobic |
| GLU 50 | B1.2 | LEU 37 | - | Hydrophobic |
| GLU 50 | B1.2 | LEU 37 | - | VdWContact |
| ILE 51 | B1.3 | VAL 33 | - | Hydrophobic |
| CYS 52 | B1.4 | HIS 36 | - | Hydrophobic |
| CYS 52 | B1.4 | HIS 36 | - | VdWContact |
| ARG 56 | b1b2.6 | GLU 207 | - | HBDonor |
| ARG 56 | b1b2.6 | GLU 207 | - | VdWContact |
| LYS 66 | B2.3 | ASP 16 | - | Cationic |
