Predicted complex interactions
CCL25_HUMAN + CXCR5
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 71
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | ALA 51 | 1.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm29 | GLY 111 | 2.64x64 | HBDonor |
| GLN 1 | NTc.Cm29 | GLY 111 | 2.64x64 | VdWContact |
| VAL 3 | NTc.Cm27 | LEU 199 | - | Hydrophobic |
| VAL 3 | NTc.Cm27 | ARG 201 | - | HBAcceptor |
| VAL 3 | NTc.Cm27 | ARG 201 | - | VdWContact |
| PHE 4 | NTc.Cm26 | ALA 40 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | ALA 40 | - | VdWContact |
| PHE 4 | NTc.Cm26 | GLU 42 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLU 42 | - | VdWContact |
| PHE 4 | NTc.Cm26 | LYS 50 | 1.31x31 | VdWContact |
| PHE 4 | NTc.Cm26 | PRO 301 | 7.32x31 | Hydrophobic |
| ASP 6 | NTc.Cm24 | LEU 37 | - | Hydrophobic |
| ASP 6 | NTc.Cm24 | CYS 38 | - | VdWContact |
| ASP 6 | NTc.Cm24 | PRO 39 | - | VdWContact |
| ASP 6 | NTc.Cm24 | ALA 40 | - | HBAcceptor |
| ASP 6 | NTc.Cm24 | ALA 40 | - | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 38 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 38 | - | VdWContact |
| CYS 8 | NTc.Cm22 | HIS 36 | - | VdWContact |
| LEU 9 | NTc.Cm21 | HIS 36 | - | HBDonor |
| LEU 9 | NTc.Cm21 | HIS 36 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 38 | - | VdWContact |
| LEU 9 | NTc.Cm21 | ASN 292 | - | VdWContact |
| LEU 9 | NTc.Cm21 | ASN 297 | 7.28x27 | Hydrophobic |
| LEU 9 | NTc.Cm21 | ASN 297 | 7.28x27 | VdWContact |
| ALA 10 | NTc.Cm20 | HIS 36 | - | Hydrophobic |
| ALA 10 | NTc.Cm20 | HIS 36 | - | VdWContact |
| HIS 12 | NTc.Cm18 | VAL 33 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | VAL 33 | - | VdWContact |
| HIS 12 | NTc.Cm18 | GLU 34 | - | VdWContact |
| HIS 12 | NTc.Cm18 | HIS 36 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | HIS 36 | - | PiStacking |
| HIS 12 | NTc.Cm18 | HIS 36 | - | VdWContact |
| ALA 18 | NTc.Cm12 | LEU 24 | - | Hydrophobic |
| ARG 21 | NTc.Cm9 | GLU 20 | - | Cationic |
| ARG 21 | NTc.Cm9 | GLU 20 | - | HBDonor |
| ARG 21 | NTc.Cm9 | GLU 20 | - | VdWContact |
| ARG 21 | NTc.Cm9 | LEU 24 | - | Hydrophobic |
| ARG 21 | NTc.Cm9 | LEU 24 | - | VdWContact |
| ARG 22 | NTc.Cm8 | LEU 24 | - | HBDonor |
| ARG 22 | NTc.Cm8 | LEU 24 | - | Hydrophobic |
| ARG 22 | NTc.Cm8 | LEU 24 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 27 | - | VdWContact |
| TYR 26 | NTc.Cm4 | ASN 196 | - | HBAcceptor |
| TYR 26 | NTc.Cm4 | ASN 196 | - | VdWContact |
| ARG 27 | NTc.Cm3 | ASN 196 | - | HBDonor |
| ARG 27 | NTc.Cm3 | ASN 196 | - | Hydrophobic |
| ARG 27 | NTc.Cm3 | ASN 196 | - | VdWContact |
| ARG 27 | NTc.Cm3 | SER 198 | - | VdWContact |
| ILE 28 | NTc.Cm2 | HIS 194 | - | Hydrophobic |
| GLU 30 | CX.1 | HIS 194 | - | VdWContact |
| VAL 31 | CX.5 | GLN 206 | - | Hydrophobic |
| VAL 31 | CX.5 | GLN 206 | - | VdWContact |
| SER 32 | cxb1.1 | ARG 286 | 6.62x62 | HBAcceptor |
| SER 32 | cxb1.1 | ARG 286 | 6.62x62 | VdWContact |
| GLY 33 | cxb1.2 | PRO 301 | 7.32x31 | VdWContact |
| SER 34 | cxb1.5 | ASN 297 | 7.28x27 | HBAcceptor |
| SER 34 | cxb1.5 | ASN 297 | 7.28x27 | VdWContact |
| ASN 36 | cxb1.8 | ARG 286 | 6.62x62 | Hydrophobic |
| ASN 36 | cxb1.8 | ARG 286 | 6.62x62 | VdWContact |
| ILE 41 | cxb1.16 | LEU 37 | - | Hydrophobic |
| LYS 46 | B1.5 | ASP 25 | - | Cationic |
| LYS 46 | B1.5 | ASP 25 | - | HBDonor |
| LYS 46 | B1.5 | ASP 25 | - | VdWContact |
| ARG 49 | b1b2.1 | ASP 29 | - | HBDonor |
| ARG 49 | b1b2.1 | ASP 29 | - | VdWContact |
| ARG 49 | b1b2.1 | SER 31 | - | HBDonor |
| LYS 50 | b1b2.2 | LEU 37 | - | Hydrophobic |
| LYS 50 | b1b2.2 | LEU 37 | - | VdWContact |
| ARG 70 | b2b3.4 | LEU 21 | - | VdWContact |
