Predicted complex interactions
CCL27_HUMAN + CXCR5
SUMMARY
- Chemokine
- CCL27_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 97
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm32 | HIS 129 | 3.32x32 | Hydrophobic |
| PHE 1 | NTc.Cm32 | HIS 129 | 3.32x32 | PiStacking |
| PHE 1 | NTc.Cm32 | HIS 129 | 3.32x32 | VdWContact |
| PHE 1 | NTc.Cm32 | TYR 275 | 6.51x51 | Hydrophobic |
| PHE 1 | NTc.Cm32 | TYR 275 | 6.51x51 | VdWContact |
| PHE 1 | NTc.Cm32 | GLU 308 | 7.39x38 | Hydrophobic |
| PHE 1 | NTc.Cm32 | GLU 308 | 7.39x38 | VdWContact |
| LEU 2 | NTc.Cm31 | VAL 54 | 1.35x35 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 58 | 1.39x39 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 58 | 1.39x39 | VdWContact |
| LEU 2 | NTc.Cm31 | ALA 107 | 2.60x60 | Hydrophobic |
| LEU 2 | NTc.Cm31 | ALA 107 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm31 | THR 305 | 7.36x35 | Hydrophobic |
| LEU 2 | NTc.Cm31 | GLU 308 | 7.39x38 | VdWContact |
| LEU 3 | NTc.Cm30 | LYS 50 | 1.31x31 | HBAcceptor |
| LEU 3 | NTc.Cm30 | LYS 50 | 1.31x31 | VdWContact |
| LEU 3 | NTc.Cm30 | PRO 301 | 7.32x31 | Hydrophobic |
| LEU 3 | NTc.Cm30 | PRO 301 | 7.32x31 | VdWContact |
| LEU 3 | NTc.Cm30 | ILE 304 | 7.35x34 | Hydrophobic |
| LEU 3 | NTc.Cm30 | THR 305 | 7.36x35 | HBDonor |
| LEU 3 | NTc.Cm30 | THR 305 | 7.36x35 | VdWContact |
| PRO 4 | NTc.Cm29 | ARG 201 | - | VdWContact |
| PRO 5 | NTc.Cm28 | GLU 42 | - | VdWContact |
| SER 6 | NTc.Cm27 | ALA 40 | - | VdWContact |
| SER 6 | NTc.Cm27 | THR 41 | - | VdWContact |
| SER 6 | NTc.Cm27 | GLU 42 | - | HBAcceptor |
| SER 6 | NTc.Cm27 | GLU 42 | - | VdWContact |
| ALA 8 | NTc.Cm25 | LEU 37 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | CYS 38 | - | VdWContact |
| CYS 9 | NTc.Cm24 | CYS 38 | - | HBAcceptor |
| CYS 9 | NTc.Cm24 | CYS 38 | - | HBDonor |
| CYS 9 | NTc.Cm24 | CYS 38 | - | VdWContact |
| CYS 10 | NTc.Cm23 | HIS 36 | - | VdWContact |
| THR 11 | NTc.Cm22 | HIS 36 | - | HBDonor |
| THR 11 | NTc.Cm22 | HIS 36 | - | VdWContact |
| THR 11 | NTc.Cm22 | CYS 38 | - | Hydrophobic |
| THR 11 | NTc.Cm22 | CYS 38 | - | VdWContact |
| THR 11 | NTc.Cm22 | ASN 292 | - | Hydrophobic |
| THR 11 | NTc.Cm22 | ASN 292 | - | VdWContact |
| THR 11 | NTc.Cm22 | ASN 297 | 7.28x27 | Hydrophobic |
| THR 11 | NTc.Cm22 | ASN 297 | 7.28x27 | VdWContact |
| GLN 12 | NTc.Cm21 | HIS 36 | - | Hydrophobic |
| GLN 12 | NTc.Cm21 | HIS 36 | - | VdWContact |
| TYR 14 | NTc.Cm19 | VAL 33 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | VAL 33 | - | VdWContact |
| LYS 16 | NTc.Cm17 | ASP 29 | - | Cationic |
| LYS 16 | NTc.Cm17 | LEU 32 | - | VdWContact |
| LEU 18 | NTc.Cm15 | VAL 33 | - | Hydrophobic |
| ASP 20 | NTc.Cm13 | TRP 19 | - | Hydrophobic |
| ASP 20 | NTc.Cm13 | TRP 19 | - | VdWContact |
| ASP 20 | NTc.Cm13 | ARG 23 | - | Anionic |
| ASP 20 | NTc.Cm13 | ARG 23 | - | HBAcceptor |
| ASP 20 | NTc.Cm13 | ARG 23 | - | VdWContact |
| LYS 21 | NTc.Cm12 | GLU 20 | - | HBDonor |
| LYS 21 | NTc.Cm12 | GLU 20 | - | VdWContact |
| LYS 21 | NTc.Cm12 | ARG 23 | - | HBDonor |
| LYS 21 | NTc.Cm12 | ARG 23 | - | Hydrophobic |
| LYS 21 | NTc.Cm12 | ARG 23 | - | VdWContact |
| LYS 21 | NTc.Cm12 | TYR 27 | - | Hydrophobic |
| LYS 21 | NTc.Cm12 | TYR 27 | - | VdWContact |
| LEU 22 | NTc.Cm11 | THR 30 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | VAL 33 | - | Hydrophobic |
| ARG 24 | NTc.Cm9 | ASP 16 | - | Cationic |
| ARG 24 | NTc.Cm9 | ASP 16 | - | HBDonor |
| ARG 24 | NTc.Cm9 | ASP 16 | - | VdWContact |
| ARG 24 | NTc.Cm9 | ARG 23 | - | VdWContact |
| GLU 30 | NTc.Cm3 | HIS 195 | - | Hydrophobic |
| GLU 30 | NTc.Cm3 | HIS 195 | - | VdWContact |
| LEU 31 | NTc.Cm2 | HIS 194 | - | Hydrophobic |
| LEU 31 | NTc.Cm2 | HIS 194 | - | VdWContact |
| GLU 33 | CX.1 | HIS 194 | - | VdWContact |
| ALA 34 | CX.5 | GLN 206 | - | Hydrophobic |
| ALA 34 | CX.5 | GLN 206 | - | VdWContact |
| ASP 35 | cxb1.1 | THR 203 | 45.51x51 | HBAcceptor |
| ASP 35 | cxb1.1 | THR 203 | 45.51x51 | VdWContact |
| GLY 36 | cxb1.2 | ARG 286 | 6.62x62 | HBAcceptor |
| GLY 36 | cxb1.2 | ARG 286 | 6.62x62 | VdWContact |
| ASP 37 | cxb1.5 | ARG 201 | - | Anionic |
| ASP 37 | cxb1.5 | ARG 201 | - | HBAcceptor |
| ASP 37 | cxb1.5 | ARG 201 | - | VdWContact |
| HIS 39 | cxb1.7 | ARG 286 | 6.62x62 | Hydrophobic |
| HIS 39 | cxb1.7 | ARG 286 | 6.62x62 | VdWContact |
| HIS 39 | cxb1.7 | ASN 297 | 7.28x27 | VdWContact |
| HIS 39 | cxb1.7 | LEU 300 | 7.31x30 | Hydrophobic |
| LEU 40 | cxb1.8 | LYS 288 | 6.64x64 | VdWContact |
| VAL 44 | cxb1.15 | LEU 37 | - | Hydrophobic |
| HIS 46 | cxb1.17 | LEU 37 | - | Hydrophobic |
| ARG 50 | B1.2 | THR 30 | - | HBDonor |
| ARG 50 | B1.2 | THR 30 | - | VdWContact |
| ARG 50 | B1.2 | ASN 35 | - | VdWContact |
| SER 51 | B1.3 | ASN 35 | - | HBDonor |
| SER 51 | B1.3 | ASN 35 | - | VdWContact |
| ILE 52 | B1.4 | VAL 33 | - | Hydrophobic |
| ILE 52 | B1.4 | VAL 33 | - | VdWContact |
| CYS 53 | B1.5 | HIS 36 | - | Hydrophobic |
| CYS 53 | B1.5 | HIS 36 | - | VdWContact |
| CYS 53 | B1.5 | LEU 37 | - | VdWContact |
