Predicted complex interactions
CCL3_HUMAN + CXCR5
SUMMARY
- Chemokine
- CCL3_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 74
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm33 | GLU 110 | 2.63x63 | Cationic |
| SER 1 | NTc.Cm33 | GLU 110 | 2.63x63 | HBDonor |
| SER 1 | NTc.Cm33 | GLU 110 | 2.63x63 | VdWContact |
| LEU 2 | NTc.Cm32 | ILE 103 | 2.56x56 | Hydrophobic |
| LEU 2 | NTc.Cm32 | VAL 125 | 3.28x28 | Hydrophobic |
| LEU 2 | NTc.Cm32 | ILE 126 | 3.29x29 | Hydrophobic |
| LEU 2 | NTc.Cm32 | HIS 129 | 3.32x32 | Hydrophobic |
| LEU 2 | NTc.Cm32 | GLU 308 | 7.39x38 | VdWContact |
| ALA 4 | NTc.Cm30 | PRO 301 | 7.32x31 | Hydrophobic |
| ALA 4 | NTc.Cm30 | ILE 304 | 7.35x34 | Hydrophobic |
| ALA 4 | NTc.Cm30 | ILE 304 | 7.35x34 | VdWContact |
| ASP 5 | NTc.Cm29 | THR 203 | 45.51x51 | VdWContact |
| ASP 5 | NTc.Cm29 | PHE 204 | 45.52x52 | HBAcceptor |
| ASP 5 | NTc.Cm29 | PHE 204 | 45.52x52 | VdWContact |
| ASP 5 | NTc.Cm29 | TRP 215 | 5.35x36 | HBAcceptor |
| ASP 5 | NTc.Cm29 | TRP 215 | 5.35x36 | VdWContact |
| ASP 5 | NTc.Cm29 | ARG 286 | 6.62x62 | HBAcceptor |
| ASP 5 | NTc.Cm29 | ARG 286 | 6.62x62 | VdWContact |
| THR 6 | NTc.Cm28 | LEU 300 | 7.31x30 | Hydrophobic |
| THR 6 | NTc.Cm28 | PRO 301 | 7.32x31 | Hydrophobic |
| THR 6 | NTc.Cm28 | PRO 301 | 7.32x31 | VdWContact |
| PRO 7 | NTc.Cm27 | ASN 297 | 7.28x27 | HBAcceptor |
| PRO 7 | NTc.Cm27 | ASN 297 | 7.28x27 | VdWContact |
| THR 8 | NTc.Cm26 | ALA 40 | - | VdWContact |
| ALA 9 | NTc.Cm25 | LEU 37 | - | Hydrophobic |
| CYS 10 | NTc.Cm24 | LEU 37 | - | VdWContact |
| CYS 10 | NTc.Cm24 | CYS 38 | - | VdWContact |
| PHE 12 | NTc.Cm22 | HIS 36 | - | HBDonor |
| PHE 12 | NTc.Cm22 | HIS 36 | - | VdWContact |
| PHE 12 | NTc.Cm22 | CYS 38 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | CYS 38 | - | VdWContact |
| PHE 12 | NTc.Cm22 | ASN 292 | - | Hydrophobic |
| PHE 12 | NTc.Cm22 | ASN 292 | - | VdWContact |
| PHE 12 | NTc.Cm22 | ASN 297 | 7.28x27 | Hydrophobic |
| PHE 12 | NTc.Cm22 | ASN 297 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm21 | HIS 36 | - | VdWContact |
| TYR 14 | NTc.Cm20 | HIS 36 | - | VdWContact |
| THR 15 | NTc.Cm19 | HIS 36 | - | VdWContact |
| ARG 17 | NTc.Cm17 | LEU 32 | - | VdWContact |
| GLN 18 | NTc.Cm16 | TYR 27 | - | HBAcceptor |
| ILE 19 | NTc.Cm15 | TYR 27 | - | Hydrophobic |
| ILE 19 | NTc.Cm15 | TYR 27 | - | VdWContact |
| ASN 22 | NTc.Cm11 | GLU 20 | - | HBDonor |
| ASN 22 | NTc.Cm11 | GLU 20 | - | VdWContact |
| PHE 23 | NTc.Cm10 | GLU 20 | - | Hydrophobic |
| PHE 23 | NTc.Cm10 | GLU 20 | - | VdWContact |
| PHE 23 | NTc.Cm10 | ARG 23 | - | Hydrophobic |
| PHE 23 | NTc.Cm10 | LEU 24 | - | Hydrophobic |
| PHE 23 | NTc.Cm10 | LEU 24 | - | VdWContact |
| PHE 28 | NTc.Cm5 | HIS 194 | - | Hydrophobic |
| PHE 28 | NTc.Cm5 | HIS 195 | - | Hydrophobic |
| PHE 28 | NTc.Cm5 | HIS 195 | - | VdWContact |
| GLN 33 | CX.1 | GLN 206 | - | Hydrophobic |
| GLN 33 | CX.1 | GLN 206 | - | VdWContact |
| GLN 33 | CX.1 | ARG 286 | 6.62x62 | HBAcceptor |
| GLN 33 | CX.1 | ARG 286 | 6.62x62 | VdWContact |
| SER 35 | cxb1.1 | LYS 288 | 6.64x64 | HBAcceptor |
| SER 35 | cxb1.1 | LYS 288 | 6.64x64 | VdWContact |
| SER 35 | cxb1.1 | ASN 292 | - | VdWContact |
| ILE 40 | cxb1.8 | LEU 37 | - | Hydrophobic |
| ILE 40 | cxb1.8 | LEU 37 | - | VdWContact |
| ARG 45 | cxb1.16 | LEU 24 | - | VdWContact |
| ARG 45 | cxb1.16 | ASP 25 | - | Cationic |
| ARG 45 | cxb1.16 | ASN 28 | - | VdWContact |
| ARG 47 | B1.2 | TYR 27 | - | HBDonor |
| ARG 47 | B1.2 | TYR 27 | - | VdWContact |
| ARG 47 | B1.2 | ASN 28 | - | VdWContact |
| ARG 47 | B1.2 | VAL 33 | - | VdWContact |
| GLN 48 | B1.3 | LEU 37 | - | Hydrophobic |
| GLN 48 | B1.3 | LEU 37 | - | VdWContact |
| GLN 48 | B1.3 | HIS 195 | - | Hydrophobic |
| GLN 48 | B1.3 | HIS 195 | - | VdWContact |
| CYS 50 | B1.5 | HIS 36 | - | Hydrophobic |
| CYS 50 | B1.5 | HIS 36 | - | VdWContact |
