Predicted complex interactions
CCL8_HUMAN + CXCR5
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 78
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | HIS 129 | 3.32x32 | CationPi |
| GLN 1 | NTc.Cm33 | HIS 129 | 3.32x32 | HBDonor |
| GLN 1 | NTc.Cm33 | HIS 129 | 3.32x32 | VdWContact |
| GLN 1 | NTc.Cm33 | ARG 219 | 5.39x40 | HBAcceptor |
| GLN 1 | NTc.Cm33 | ARG 219 | 5.39x40 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 275 | 6.51x51 | VdWContact |
| GLN 1 | NTc.Cm33 | GLU 308 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm33 | GLU 308 | 7.39x38 | HBDonor |
| GLN 1 | NTc.Cm33 | GLU 308 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm32 | ILE 126 | 3.29x29 | Hydrophobic |
| PRO 2 | NTc.Cm32 | ILE 126 | 3.29x29 | VdWContact |
| ASP 3 | NTc.Cm31 | LYS 50 | 1.31x31 | Anionic |
| ASP 3 | NTc.Cm31 | THR 305 | 7.36x35 | HBAcceptor |
| ASP 3 | NTc.Cm31 | THR 305 | 7.36x35 | VdWContact |
| SER 4 | NTc.Cm30 | CYS 202 | 45.50x50 | HBDonor |
| SER 4 | NTc.Cm30 | CYS 202 | 45.50x50 | VdWContact |
| SER 4 | NTc.Cm30 | THR 203 | 45.51x51 | VdWContact |
| VAL 5 | NTc.Cm29 | ILE 304 | 7.35x34 | Hydrophobic |
| SER 6 | NTc.Cm28 | LYS 50 | 1.31x31 | HBAcceptor |
| SER 6 | NTc.Cm28 | LYS 50 | 1.31x31 | VdWContact |
| SER 6 | NTc.Cm28 | ARG 201 | - | HBAcceptor |
| SER 6 | NTc.Cm28 | ARG 201 | - | VdWContact |
| SER 6 | NTc.Cm28 | PRO 301 | 7.32x31 | VdWContact |
| ILE 7 | NTc.Cm27 | ARG 201 | - | Hydrophobic |
| ILE 7 | NTc.Cm27 | ARG 201 | - | VdWContact |
| ILE 7 | NTc.Cm27 | THR 203 | 45.51x51 | Hydrophobic |
| ILE 7 | NTc.Cm27 | THR 203 | 45.51x51 | VdWContact |
| PRO 8 | NTc.Cm26 | ALA 40 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | ALA 40 | - | VdWContact |
| THR 10 | NTc.Cm24 | LEU 37 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | HIS 195 | - | HBDonor |
| THR 10 | NTc.Cm24 | HIS 195 | - | VdWContact |
| CYS 11 | NTc.Cm23 | HIS 36 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 38 | - | VdWContact |
| PHE 13 | NTc.Cm21 | HIS 36 | - | HBDonor |
| PHE 13 | NTc.Cm21 | HIS 36 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | HIS 36 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 38 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 38 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ASN 292 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | ASN 292 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ASN 297 | 7.28x27 | Hydrophobic |
| PHE 13 | NTc.Cm21 | ASN 297 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | VAL 33 | - | Hydrophobic |
| ASN 14 | NTc.Cm20 | VAL 33 | - | VdWContact |
| ASN 14 | NTc.Cm20 | HIS 36 | - | Hydrophobic |
| ASN 14 | NTc.Cm20 | HIS 36 | - | VdWContact |
| ILE 16 | NTc.Cm18 | LEU 32 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | TYR 27 | - | CationPi |
| ARG 18 | NTc.Cm16 | TYR 27 | - | VdWContact |
| ARG 18 | NTc.Cm16 | LEU 32 | - | VdWContact |
| ILE 20 | NTc.Cm14 | TYR 27 | - | VdWContact |
| ARG 24 | NTc.Cm10 | GLU 20 | - | Cationic |
| ARG 24 | NTc.Cm10 | GLU 20 | - | HBDonor |
| ARG 24 | NTc.Cm10 | GLU 20 | - | VdWContact |
| ARG 24 | NTc.Cm10 | LEU 24 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TYR 27 | - | CationPi |
| THR 29 | NTc.Cm5 | HIS 194 | - | Hydrophobic |
| THR 29 | NTc.Cm5 | HIS 194 | - | VdWContact |
| ILE 34 | CX.1 | THR 212 | - | Hydrophobic |
| ILE 34 | CX.1 | THR 212 | - | VdWContact |
| GLN 35 | CX.5 | GLN 206 | - | HBDonor |
| GLN 35 | CX.5 | GLN 206 | - | VdWContact |
| GLN 35 | CX.5 | ARG 286 | 6.62x62 | HBAcceptor |
| GLN 35 | CX.5 | ARG 286 | 6.62x62 | Hydrophobic |
| GLN 35 | CX.5 | ARG 286 | 6.62x62 | VdWContact |
| PRO 37 | cxb1.2 | LYS 288 | 6.64x64 | HBAcceptor |
| PRO 37 | cxb1.2 | LYS 288 | 6.64x64 | VdWContact |
| ILE 42 | cxb1.10 | LEU 37 | - | Hydrophobic |
| ILE 42 | cxb1.10 | LEU 37 | - | VdWContact |
| ILE 42 | cxb1.10 | HIS 195 | - | Hydrophobic |
| ARG 47 | B1.1 | LEU 24 | - | VdWContact |
| LYS 49 | B1.3 | GLU 34 | - | Cationic |
| LYS 49 | B1.3 | GLU 34 | - | HBDonor |
| LYS 49 | B1.3 | GLU 34 | - | VdWContact |
| GLU 50 | B1.4 | LEU 37 | - | Hydrophobic |
| GLU 50 | B1.4 | LEU 37 | - | VdWContact |
| CYS 52 | B1.6 | LEU 37 | - | VdWContact |
