Predicted complex interactions
CX3CL1_HUMAN + CXCR5
SUMMARY
- Chemokine
- CX3CL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 82
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm37 | ILE 103 | 2.56x56 | VdWContact |
| GLN 1 | NTc.Cm37 | ALA 107 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm37 | GLU 110 | 2.63x63 | HBDonor |
| GLN 1 | NTc.Cm37 | GLU 110 | 2.63x63 | VdWContact |
| GLN 1 | NTc.Cm37 | TRP 115 | 23.50x50 | VdWContact |
| GLN 1 | NTc.Cm37 | VAL 125 | 3.28x28 | VdWContact |
| GLN 1 | NTc.Cm37 | GLU 308 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm37 | GLU 308 | 7.39x38 | HBDonor |
| GLN 1 | NTc.Cm37 | GLU 308 | 7.39x38 | VdWContact |
| HIS 2 | NTc.Cm36 | ILE 126 | 3.29x29 | Hydrophobic |
| HIS 2 | NTc.Cm36 | ILE 126 | 3.29x29 | VdWContact |
| HIS 2 | NTc.Cm36 | HIS 129 | 3.32x32 | HBAcceptor |
| HIS 2 | NTc.Cm36 | HIS 129 | 3.32x32 | Hydrophobic |
| HIS 2 | NTc.Cm36 | HIS 129 | 3.32x32 | VdWContact |
| HIS 2 | NTc.Cm36 | LYS 130 | 3.33x33 | Hydrophobic |
| HIS 2 | NTc.Cm36 | LYS 130 | 3.33x33 | VdWContact |
| HIS 2 | NTc.Cm36 | GLU 184 | 4.60x61 | Hydrophobic |
| HIS 2 | NTc.Cm36 | GLU 308 | 7.39x38 | HBDonor |
| HIS 2 | NTc.Cm36 | GLU 308 | 7.39x38 | VdWContact |
| HIS 3 | NTc.Cm35 | PRO 301 | 7.32x31 | VdWContact |
| HIS 3 | NTc.Cm35 | ILE 304 | 7.35x34 | HBDonor |
| HIS 3 | NTc.Cm35 | ILE 304 | 7.35x34 | Hydrophobic |
| HIS 3 | NTc.Cm35 | ILE 304 | 7.35x34 | VdWContact |
| HIS 3 | NTc.Cm35 | THR 305 | 7.36x35 | HBDonor |
| HIS 3 | NTc.Cm35 | THR 305 | 7.36x35 | VdWContact |
| HIS 3 | NTc.Cm35 | GLU 308 | 7.39x38 | Hydrophobic |
| HIS 3 | NTc.Cm35 | GLU 308 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm34 | THR 203 | 45.51x51 | VdWContact |
| VAL 5 | NTc.Cm33 | THR 203 | 45.51x51 | VdWContact |
| VAL 5 | NTc.Cm33 | ARG 286 | 6.62x62 | VdWContact |
| THR 6 | NTc.Cm32 | SER 191 | - | HBDonor |
| LYS 7 | NTc.Cm31 | ALA 40 | - | Hydrophobic |
| LYS 7 | NTc.Cm31 | ALA 40 | - | VdWContact |
| LYS 7 | NTc.Cm31 | GLU 42 | - | Cationic |
| LYS 7 | NTc.Cm31 | GLU 42 | - | HBDonor |
| LYS 7 | NTc.Cm31 | GLU 42 | - | VdWContact |
| LYS 7 | NTc.Cm31 | PRO 301 | 7.32x31 | Hydrophobic |
| LYS 7 | NTc.Cm31 | PRO 301 | 7.32x31 | VdWContact |
| CYS 8 | NTc.Cm30 | ALA 40 | - | VdWContact |
| ASN 9 | NTc.Cm29 | ALA 40 | - | HBAcceptor |
| ASN 9 | NTc.Cm29 | ALA 40 | - | VdWContact |
| ASN 9 | NTc.Cm29 | HIS 195 | - | Hydrophobic |
| ASN 9 | NTc.Cm29 | HIS 195 | - | VdWContact |
| ILE 10 | NTc.Cm28 | LEU 37 | - | Hydrophobic |
| ILE 10 | NTc.Cm28 | LEU 37 | - | VdWContact |
| ILE 10 | NTc.Cm28 | HIS 195 | - | Hydrophobic |
| THR 11 | NTc.Cm27 | HIS 36 | - | VdWContact |
| THR 11 | NTc.Cm27 | CYS 38 | - | HBAcceptor |
| THR 11 | NTc.Cm27 | CYS 38 | - | VdWContact |
| THR 11 | NTc.Cm27 | ASN 297 | 7.28x27 | Hydrophobic |
| CYS 12 | NTc.Cm26 | HIS 36 | - | VdWContact |
| SER 13 | NTc.Cm25 | HIS 36 | - | HBDonor |
| SER 13 | NTc.Cm25 | HIS 36 | - | VdWContact |
| LYS 14 | NTc.Cm24 | HIS 36 | - | Hydrophobic |
| LYS 14 | NTc.Cm24 | HIS 36 | - | VdWContact |
| THR 16 | NTc.Cm22 | TYR 27 | - | HBAcceptor |
| THR 16 | NTc.Cm22 | TYR 27 | - | VdWContact |
| SER 17 | NTc.Cm21 | TYR 27 | - | HBDonor |
| SER 17 | NTc.Cm21 | TYR 27 | - | VdWContact |
| ILE 19 | NTc.Cm19 | TYR 27 | - | Hydrophobic |
| PRO 20 | NTc.Cm18 | GLU 20 | - | Hydrophobic |
| PRO 20 | NTc.Cm18 | GLU 20 | - | VdWContact |
| LEU 23 | NTc.Cm15 | GLU 20 | - | Hydrophobic |
| LEU 23 | NTc.Cm15 | LEU 24 | - | Hydrophobic |
| LEU 23 | NTc.Cm15 | LEU 24 | - | VdWContact |
| GLN 28 | NTc.Cm10 | HIS 194 | - | VdWContact |
| GLN 28 | NTc.Cm10 | HIS 195 | - | VdWContact |
| ALA 32 | NTc.Cm6 | GLN 206 | - | VdWContact |
| ALA 32 | NTc.Cm6 | GLU 207 | - | VdWContact |
| LYS 36 | NTc.Cm2 | LYS 288 | 6.64x64 | VdWContact |
| GLN 45 | cxb1.5 | ASN 28 | - | HBDonor |
| GLN 45 | cxb1.5 | ASN 28 | - | VdWContact |
| ARG 47 | cxb1.8 | TYR 27 | - | HBDonor |
| ARG 47 | cxb1.8 | TYR 27 | - | VdWContact |
| ARG 47 | cxb1.8 | ASN 28 | - | VdWContact |
| LEU 48 | cxb1.10 | VAL 33 | - | VdWContact |
| LEU 48 | cxb1.10 | LEU 37 | - | Hydrophobic |
| LEU 48 | cxb1.10 | LEU 37 | - | VdWContact |
| PHE 49 | cxb1.11 | TYR 27 | - | Hydrophobic |
| PHE 49 | cxb1.11 | TYR 27 | - | VdWContact |
| PHE 49 | cxb1.11 | VAL 33 | - | Hydrophobic |
| PHE 49 | cxb1.11 | VAL 33 | - | VdWContact |
