Predicted complex interactions
CXCL10_HUMAN + CXCR5
SUMMARY
- Chemokine
- CXCL10_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CXCR5 View partner entry
- Partner description
- UniProt: P32302; Gene: cxcr5_human; Family: Chemokine
- Interactions detected
- 105
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm29 | VAL 54 | 1.35x35 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TYR 58 | 1.39x39 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TYR 58 | 1.39x39 | VdWContact |
| VAL 1 | NTc.Cm29 | GLU 110 | 2.63x63 | Cationic |
| VAL 1 | NTc.Cm29 | THR 305 | 7.36x35 | Hydrophobic |
| VAL 1 | NTc.Cm29 | THR 305 | 7.36x35 | VdWContact |
| VAL 1 | NTc.Cm29 | GLU 308 | 7.39x38 | Hydrophobic |
| VAL 1 | NTc.Cm29 | GLU 308 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm28 | ALA 107 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm28 | ALA 107 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm28 | GLU 110 | 2.63x63 | VdWContact |
| LEU 3 | NTc.Cm27 | ILE 126 | 3.29x29 | Hydrophobic |
| LEU 3 | NTc.Cm27 | ILE 126 | 3.29x29 | VdWContact |
| LEU 3 | NTc.Cm27 | HIS 129 | 3.32x32 | Hydrophobic |
| LEU 3 | NTc.Cm27 | HIS 129 | 3.32x32 | VdWContact |
| LEU 3 | NTc.Cm27 | LYS 130 | 3.33x33 | Hydrophobic |
| LEU 3 | NTc.Cm27 | LYS 130 | 3.33x33 | VdWContact |
| SER 4 | NTc.Cm26 | ARG 219 | 5.39x40 | HBAcceptor |
| SER 4 | NTc.Cm26 | ARG 219 | 5.39x40 | VdWContact |
| SER 4 | NTc.Cm26 | ILE 304 | 7.35x34 | VdWContact |
| ARG 5 | NTc.Cm25 | ARG 201 | - | VdWContact |
| THR 6 | NTc.Cm24 | TRP 215 | 5.35x36 | Hydrophobic |
| THR 6 | NTc.Cm24 | ASP 282 | 6.58x58 | VdWContact |
| THR 6 | NTc.Cm24 | ARG 286 | 6.62x62 | VdWContact |
| VAL 7 | NTc.Cm23 | ARG 286 | 6.62x62 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 282 | 6.58x58 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 282 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm22 | ASP 282 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm22 | ASN 297 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm22 | LEU 300 | 7.31x30 | VdWContact |
| CYS 9 | NTc.Cm21 | ASN 297 | 7.28x27 | HBAcceptor |
| CYS 9 | NTc.Cm21 | ASN 297 | 7.28x27 | VdWContact |
| THR 10 | NTc.Cm20 | CYS 38 | - | VdWContact |
| THR 10 | NTc.Cm20 | HIS 195 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | HIS 36 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 38 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 38 | - | VdWContact |
| ILE 12 | NTc.Cm18 | ASN 292 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | ASN 292 | - | VdWContact |
| ILE 12 | NTc.Cm18 | ASN 297 | 7.28x27 | Hydrophobic |
| ILE 12 | NTc.Cm18 | ASN 297 | 7.28x27 | VdWContact |
| SER 13 | NTc.Cm17 | HIS 36 | - | HBAcceptor |
| SER 13 | NTc.Cm17 | HIS 36 | - | VdWContact |
| SER 15 | NTc.Cm15 | HIS 36 | - | VdWContact |
| GLN 17 | NTc.Cm13 | ASP 29 | - | VdWContact |
| GLN 17 | NTc.Cm13 | SER 31 | - | VdWContact |
| PRO 18 | NTc.Cm12 | LEU 24 | - | Hydrophobic |
| ASN 20 | NTc.Cm10 | ASP 25 | - | HBDonor |
| ASN 20 | NTc.Cm10 | ASP 25 | - | VdWContact |
| PRO 21 | NTc.Cm9 | PHE 18 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | PHE 18 | - | VdWContact |
| PRO 21 | NTc.Cm9 | LEU 21 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | LEU 21 | - | VdWContact |
| PRO 21 | NTc.Cm9 | ASP 22 | - | VdWContact |
| ARG 22 | NTc.Cm8 | ASP 22 | - | Cationic |
| LEU 24 | NTc.Cm6 | LEU 11 | - | Hydrophobic |
| LEU 24 | NTc.Cm6 | LEU 11 | - | VdWContact |
| LYS 26 | NTc.Cm4 | GLU 8 | - | Cationic |
| LYS 26 | NTc.Cm4 | GLU 8 | - | HBDonor |
| LYS 26 | NTc.Cm4 | GLU 8 | - | VdWContact |
| LEU 27 | NTc.Cm3 | LEU 7 | - | VdWContact |
| LEU 27 | NTc.Cm3 | LEU 11 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | LEU 5 | - | VdWContact |
| ILE 30 | CX.1 | HIS 194 | - | Hydrophobic |
| ILE 30 | CX.1 | HIS 194 | - | VdWContact |
| ILE 30 | CX.1 | HIS 195 | - | Hydrophobic |
| PRO 31 | CX.4 | PRO 4 | - | Hydrophobic |
| PRO 31 | CX.4 | HIS 194 | - | Hydrophobic |
| PRO 31 | CX.4 | HIS 194 | - | VdWContact |
| SER 33 | cxb1.1 | HIS 194 | - | VdWContact |
| GLN 34 | cxb1.2 | SER 191 | - | VdWContact |
| GLN 34 | cxb1.2 | SER 205 | - | VdWContact |
| GLN 34 | cxb1.2 | GLN 206 | - | VdWContact |
| GLN 34 | cxb1.2 | GLU 207 | - | HBDonor |
| GLN 34 | cxb1.2 | GLU 207 | - | Hydrophobic |
| GLN 34 | cxb1.2 | GLU 207 | - | VdWContact |
| PHE 35 | cxb1.5 | SER 191 | - | VdWContact |
| PHE 35 | cxb1.5 | THR 203 | 45.51x51 | Hydrophobic |
| PHE 35 | cxb1.5 | THR 203 | 45.51x51 | VdWContact |
| ILE 42 | cxb1.15 | LEU 37 | - | Hydrophobic |
| ILE 42 | cxb1.15 | LEU 37 | - | VdWContact |
| GLU 50 | B1.7 | VAL 33 | - | Hydrophobic |
| GLU 50 | B1.7 | VAL 33 | - | VdWContact |
| GLU 50 | B1.7 | ASN 35 | - | VdWContact |
| LYS 51 | b1b2.4 | LEU 37 | - | Hydrophobic |
| LYS 51 | b1b2.4 | LEU 37 | - | VdWContact |
| ARG 52 | b1b2.6 | ASP 29 | - | Cationic |
| CYS 53 | b1b2.7 | HIS 36 | - | Hydrophobic |
| CYS 53 | b1b2.7 | LEU 37 | - | VdWContact |
| ALA 60 | b1b2.16 | LEU 21 | - | Hydrophobic |
| ALA 60 | b1b2.16 | LEU 24 | - | Hydrophobic |
| ASN 63 | B2.3 | GLU 20 | - | VdWContact |
| LEU 64 | B2.4 | LEU 17 | - | Hydrophobic |
| LEU 64 | B2.4 | LEU 17 | - | VdWContact |
| LEU 64 | B2.4 | LEU 21 | - | Hydrophobic |
| LEU 64 | B2.4 | LEU 21 | - | VdWContact |
| ALA 67 | b2b3.2 | LEU 17 | - | Hydrophobic |
| ALA 67 | b2b3.2 | LEU 17 | - | VdWContact |
| VAL 68 | b2b3.3 | LEU 7 | - | Hydrophobic |
| VAL 68 | b2b3.3 | LEU 7 | - | VdWContact |
| VAL 68 | b2b3.3 | MET 9 | - | Hydrophobic |
| VAL 68 | b2b3.3 | MET 9 | - | VdWContact |
| VAL 68 | b2b3.3 | LEU 17 | - | Hydrophobic |
| GLU 71 | b2b3.12 | LEU 14 | - | Hydrophobic |
| ARG 72 | B3.1 | LEU 5 | - | VdWContact |
